Presentation Information
[8p-C214-6]In-plane compressive response induced in planar lipid bilayers by horizontal membrane electric fields
〇Hironori Kageyama1, Maki Komiya1, Eiji Yamamoto2, Ayumi Hirano-Iwata1,3 (1.RIEC, Tohoku Univ., 2.Keio Univ., 3.AIMR, Tohoku Univ.)
Keywords:
cell membrane,horizontal membrane electric field,lipid bilayer
In this study, we investigated the effects of horizontal membrane electric fields on the structural and mechanical properties of planar lipid bilayers using bright-field imaging and capacitance measurements. We found that application of a horizontal membrane electric field reversibly decreased both the membrane area and the electrical capacitance, accompanied by a history-dependent response. These findings extend the conventional framework, in which the membrane potential has been treated primarily as a vertical electric field across the membrane, and position horizontal membrane electric fields as a new physical factor governing membrane properties.