[9a-E301-1~11] 12.6 Nanobiotechnology

11:45 AM - 12:00 PM JST(2:45 AM - 3:00 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[9a-E301-11] Tip-Enhanced Raman Spectroscopy for Chemical-State Analysis of MoS₂–Peptide Interfaces

〇(D)Yumie Nishiyama¹, Balaji Sanap², Yano Taka-aki^2,3, Hayamizu Yumie¹ (1.Science Tokyo, 2.Tokushima Univ., 3.RIKEN)

Keywords:

Biosensor,Nano-spectroscopy

Two-dimensional materials such as graphene and MoS₂ have emerged as promising platforms for biosensor applications. However, the chemical-state characterization of peptide monolayers formed on their surfaces remains challenging. Here, we apply tip-enhanced Raman spectroscopy (TERS) to investigate the local chemical states of peptide monolayers and peptide–hemin composite films on MoS₂. Near-field-enhanced Raman signals were successfully detected only when the metallic tip was brought into close proximity to the sample surface. The results demonstrate the feasibility of TERS for chemical-state analysis of MoS₂–peptide interfaces.