Presentation Information
[9a-E301-2]Correlation between Co-Assembly Structure of Biotin-Functionalized Peptides and their Electrical Response against Avidin
〇Yuito Takahashi1, Chishu Homma1, Yuhei Hayamizu1 (1.Science Tokyo)
Keywords:
self-assembly,Graphene,bioelectronics
Peptides can spontaneously self-assemble on two-dimentional material surfaces and form ordered nanostructures depending on their amino acid sequences. Such self-assembled peptide layers have attracted attention as functional interfaces for biosensing and molecular recognition devices. In this study, we investigate co-assembled peptide monolayers consisting of scaffold peptides and peptides modified with functional molecules. The effects of the mixing ratio on interfacial structure and electrical responses associated with molecular recognition are evaluated. Surface morphologies are characterized by atomic force microscopy (AFM), while molecular recognition events are monitored using graphene field-effect transistor (GFET) measurements. By correlating structural properties with electrical responses, this work aims to provide design guidelines for peptide-based bioelectronic interfaces and molecular recognition platforms.