[9p-E301-1~10] Learning from life, transcending life: Total Biomimetics Connecting Materials, Medicine, and Social Implementation

2:55 PM - 3:35 PM JST(5:55 AM - 6:35 AM UTC)

[9p-E301-4] Drug discovery using tumor-transplanted chicken eggs as radio-/sono-sensitizers and therapeutic effects of the immunomodulatory protein on autoimmune diseases

〇Yoshihiro Uto¹, Yusei Shinohara¹, Yoshio Endo², Toshio Inui³ (1.Tokushima Univ., 2.Kanazawa Univ., 3.Saisei Mirai Clinics)

Keywords:

tumor-transplanted chicken eggs,radio/sonosensitizer,GcMAF

Tumor-transplanted chicken eggs are an animal model in which tumor cells are transplanted into the chaloallantoic membrane of developing chicken eggs. Compared to mice, they allow for simpler and faster observation of antitumor effects, making them suitable for drug screening trials. We are conducting drug discovery on radiosensitizers and sonosensitizers using this model, as well as clinical research on colostrum MAF, which we developed using macrophage activator GcMAF as a lead compound, for use in autoimmune diseases. At this symposium, we would like to present an overview of these research results and our venture activities.