[15a-WL1_301-1~11] 12.7 Biomedical Engineering and Biochips

10:30 AM - 10:45 AM JST(1:30 AM - 1:45 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation AwardEnglish Presentation

[15a-WL1_301-6] Wireless Passive Smart Contact Lens for Simultaneous Monitoring of Corneal Hydration and Tear Osmolarity

〇(M2)Mengping Ke¹, Te Xiao¹, Saman Azhari¹, Gabor Mehes¹, Takeo Miyake¹ (1.Waseda Univ.)

Keywords:

Smart Contact Lens,Dry Eye Syndrome,Continuous Monitoring

Conventional invasive diagnostics for Dry Eye Syndrome (DES) cannot provide continuous monitoring. Although smart contact lenses have enabled wireless detection of tear biomarkers such as glucose [1] and cholesterol [2], independent quantification of corneal hydration and tear salinity remains challenging due to RF signal cross-sensitivity. Here, we present a passive smart contact lens integrating a micrometer-thick LC resonant sensor [3] and an ultrathin polyacrylamide hydrogel sensing layer fabricated via UV-initiated in-situ polymerization. Corneal hydration induces hydrogel swelling and dielectric changes, leading to resonance frequency shifts, while tear salinity affects dielectric loss (ε''), altering the signal magnitude, enabling effective signal decoupling. Experimental results demonstrate stable dual-parameter monitoring, supporting improved phenotyping of hyperosmolar dry eye syndrome.