Presentation Information
[15p-S2_203-6]Why Do Cells Favor Helical Structures?
〇Michiya Matsusaki1, Zhuying Zhang1, Kenta Homma1, Chie Hosokawa2, Takashige Omatsu3 (1.Grad. Sch. Eng., The Univ. of Osaka, 2.Grad. Sch. Sci., Osaka Metro. Univ., 3.Grad. Sch. Eng., Chiba Univ.)
Keywords:
Cell,Helical structures,Tissue engineering
No perfect linear structure exists in biological tissues and living tissues have helical structures such as the double helix of DNA at the molecular level, the collagen triple helix at micrometer level, and the helical structures of blood vessels at the millimeter level, respectively. Why do living organisms prefer helical structures? There have been no reports to reproduce the helical structures mimicking living organisms. In this study, we focused on optical vortex to construct cell-scaffold tissues with helical structures at micrometer pitch and to analyze cellular functions. We expect to understand the meaning and functions of helical structures and develop them into creative “helical tissue engineering” technology.
