[16a-PB1-1~5] 3.3 Biomedical optics

[16a-PB1-3] Development of a droplet concentration Raman spectroscopy system
for therapeutic drug monitoring.

〇(M2)Ginichi Kato¹, Terumasa Ito¹, Gen Hayase², Daisuke Yoshino¹, Kazuhiko Misawa¹ (1.Tokyo University of Agriculture and Technology[TUAT], 2.National Institute for Materials Science[NIMS])

Keywords:

Raman Spectroscopy,Therapeutic Drug Monitoring,Measurement of drug concentration

Therapeutic drug monitoring (TDM) is essential for the safe and effective treatment of high-risk drugs. In this study, Raman spectroscopy using droplet concentration is investigated toward rapid measurement of drug concentrations in blood. Protein-removed samples from a drug-containing serum model are measured under humidified conditions, and the quantitative accuracy of the concentration is discussed.