Presentation Information
[16p-W2_402-2]Self-assembly of histidine-containing peptides in the presence of metal ions
〇Asahi Yu1, Yuhei Hayamizu1 (1.Science Tokyo)
Keywords:
peptides,self-assembly,metal ions
Self-assembling peptides form ordered structures on the surfaces of two-dimensional materials. Recent studies have demonstrated the immobilization of the catalytic cofactor hemin on peptide self-assembled structures, suggesting the potential of metal-ion-mediated intermolecular interactions. In this study, LH4 peptides composed of repeating leucine and histidine residues were self-assembled on graphite surfaces, and the effect of Ni2+ on structural formation was evaluated. Atomic force microscopy revealed an increase in the height of the assembled structures in the presence of NiCl2, demonstrating that metal ions influence the peptide self-assembly on graphite.