[16p-WL1_301-1~9] Next-Generation Biomedical Applications: Pioneered by Magneto-Science and Medical-Engineering Integration

2:45 PM - 3:15 PM JST(5:45 AM - 6:15 AM UTC)

[16p-WL1_301-3] Bio-Sensing and Neuronal Stimulation Using Magnetic Fields

〇Masaki Sekino¹, Kanta Komuro¹, Anna Iino¹, Tingyu Zhu¹, Cao Xinyu¹, Motofumi Fushimi¹, Yuta Kainuma², Naota Sekiguchi³, Takayuki Iwasaki³, Mutsuko Hatano³ (1.Univ. Tokyo, 2.AIST, 3.Science Tokyo)

Keywords:

biomagnetics

Noninvasive techniques for measuring and modulating neural activity are important in neuroscience and medicine. Electrical methods are hindered by tissue conductivity inhomogeneity, whereas magnetic fields allow more accurate estimation and control because biological tissues have magnetic permeability close to vacuum. Recent advances in sensitive magnetic sensors, especially optically pumped magnetometers, have enabled compact and wearable magnetoencephalography (MEG) systems that allow subject movement. To realize real-world MEG, we are developing sensor systems robust to magnetic noise, focusing on solid-state quantum sensors based on nitrogen-vacancy centers in diamond. Our work includes magnetic probes for detecting nanoparticle-labeled lymph nodes and measurements of cardiac magnetic fields, with ongoing development of animal and human MEG systems. For neural stimulation, inverse electromagnetic design methods were developed to optimize coil windings, achieving deeper brain stimulation, along with fabrication of three-dimensional, liquid-cooled coils with improved field control and cooling performance.