Presentation Information

[17a-WL2_101-6]All-Optical Classification of Cell Transmitted-Light Data Using Diffractive Neural Networks: A Simulation Study

〇(M1)Norihide Sagami1, Yueyun Weng2, Cheng Lei2, Ryosuke oketani1, Kotaro Hiramatsu1 (1.Kyushu Univ., 2.Wuhan Univ.)

Keywords:

optical neural network,bioimaging

Diffractive neural networks (DNNs) have attracted attention as an ultrafast signal processing technology that exploits optical diffraction and interference for computation. Although DNN-based classification has been demonstrated for simple images such as MNIST, DNN analysis of cellular images has not yet been validated. In this study, we performed a DNN-based cell classification simulation using amplitude–phase pairs of transmitted light acquired by large-scale quantitative phase imaging, and demonstrated a classification accuracy of 96.1% for lung cancer cells, breast cancer cells, and leukocytes (N = 4800).