Presentation Information
[17p-PB1-9]Flexible pH and lactate sensors with sweat-induced device
〇(B)Thanyapat Suthisongtham1, Juri Ohno1, Mai Tanaka1, Kuniharu Takei1 (1.Hokkaido Univ.)
Keywords:
Flexible Device
To advance preventative medicine and address the limitation of exercise-dependent chemical sensing, this study presents an integrated multimodal patch on a flexible PET substrate capable of on-demand sweat extraction and analysis for accurate telediagnosis. The device combines a Polyaniline-based pH sensor and a lactate sensor fabricated by coating an Au electrode with a Prussian Blue (PB)/Carbon Nanotube (CNT) composite, subsequently functionalized with an immobilized Lactate Oxidase (LOx)/chitosan layer. These sensors are integrated with an iontophoresis module comprising a carbon black/Ag electrode and an acetylcholine-loaded agarose hydrogel. Experimental results demonstrated a high pH sensitivity of 61.8 mV/pH with robust stability, alongside precise lactate detection in the low-micromolar range suitable for monitoring physiological fluctuations. Furthermore, the iontophoresis unit successfully induced localized perspiration via a ~100 µA current, validating the platform's feasibility for real-time, simultaneous biomarker monitoring without physical exertion, thus offering a practical solution for accessible home-based healthcare.