[18a-PB2-1~21] 12.7 Biomedical Engineering and Biochips

[18a-PB2-2] Spontaneous Morphological Deformation Driven by Traction Forces of Aligned Cells

〇(M1)Yang Jin¹, Mino Akitaya¹, Daigo Natsuhara¹, Hisataka Maruyama¹, Takayuki Hoshino¹ (1.Nagoya Univ.)

Keywords:

collective cell,cell-cell interaction,morphogenesis

Cells interact and behave cooperatively to realize biological phenomena.Here, we investigate how information transmission within cell collectives leads to coordinated behavior.Aligned cells on a scaffold generated traction forces, inducing spontaneous scaffold deformation, indicating that cell collectives can autonomously regulate forces and produce collective morphological responses.