Session Details
[Japanese session]New Frontier in ubiquitin research
Tue. Jun 28, 2022 5:00 PM - 7:30 PM JST
Tue. Jun 28, 2022 8:00 AM - 10:30 AM UTC
Tue. Jun 28, 2022 8:00 AM - 10:30 AM UTC
Venue D Tougen
Organizer: Yasushi Saeki (Tokyo Metropolitan Institute of Medical Science)
Protein ubiquitylation is an essential post-translational modification that regulates almost all cellular functions. In this session, we will introduce new topics in ubiquitin research, including ubiquitin-dependent phase separation of cellular machineries, related diseases, and the implementation of recently emerging chemical tools such as artificial antibodies and chemical protein degraders.
opening remarks
[1D-118]The role of nuclear proteasome foci in senescent cells
*Shigeo Murata1 (1. Graduate School of Pharmaceutical Sciences, the University of Tokyo)
[1D-119]Proteostatic regulation in quiescence of neural stem cells
*Taeko Kobayashi1 (1. Graduate School of Biostudies, Kyoto University)
[1D-120]New insights of proteasomal ubiquitin decoders
*Yasushi Saeki1, Hikaru Tsuchiya1, Gosuke Hayashi2, Akinori Endo2,1 (1. Tokyo Metropolitan Institute of Medical Science, 2. Nagoya Univ., Dept. of Biomol. Eng.)
[1D-121]Mitochondrial degradation regulated by autophagy adaptors
*Koji Yamano1 (1. Tokyo Metropolitan Institute of Medical Science)
[1D-122]Small molecules that induce degradation of intracellular target proteins
*Minoru Ishikawa1 (1. Graduate School of Life Sciences, Tohoku University)
[1D-123]Development of inhibitors targeting a linear ubiquitin chain-generating enzyme and their basic studies as therapeutic agents for diseases.
*Daisuke Oikawa1, Qiang Zhang1, Seigo Terawaki1,2, Yoshinori Okina1, Yoshinosuke Usuki3, Fuminori Tokunaga1 (1. Department of Medical Biochemistry, Graduate School of Medicine, Osaka Metropolitan University., 2. Department of Molecular and Genetic Medicine, Kawasaki Medical School., 3. Department of Chemistry, Graduate School of Science, Osaka Metropolitan University.)