Session Details

[P1-03]Poster Session 1-03 Cancer Genetics 1

Thu. Oct 10, 2024 4:50 PM - 5:50 PM JST
Thu. Oct 10, 2024 7:50 AM - 8:50 AM UTC
Poster Room

[P1-03-1]Blood relative diagnosis of HBOC and issues at our hospital

Yukiko Yoshimoto, Ai Itagaki, Tsuyoshi Tachibana, Sachiko Takahara (Department of Breast Surgery, Kitano Hospital, Osaka, Japan)

[P1-03-2]Three patients with BRCA2 pathogenic variants requiring special interpret

Midori Noma1,2, Mihoko Doi1, Yuko Shiroyama1,3, Kanako Iwami1, Hanae Satano1, Yukiko Kajiwara4, Yusaku Urakawa5, Hideki Yamamoto5, Akira Hirasawa5, Yasuko Yamamoto6 (1.Department of Genomic Medicine, Hiroshima Prefectural Hospital, 2.Department of Breast Surgery, Hiroshima Prefectural Hospital, 3.Department of Obstetrics and Gynecology, Hiroshima Prefectural Hospital, 4.Department of Breast Surgery, Hiroshima City Hiroshima Citizens Hospital, 5.Department of Clinical Genomic Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 6.Department of Hereditary Cancer, National Hospital Organization, Shikoku Cancer Center)

[P1-03-3]Three cases of HBOC syndrome with breast cancer detected during breast surveillance

Mizuho Takahashi1, Hiroyuki Maeda1, Hiroko Kouno1, Kazumi Ikeda2, Yoshiaki Imamura3, Hideaki Tsuyoshi4, Masamichi Ikawa2, Takanori Goi1 (1.Department of First Surgery, University of Fukui, Fukui, Japan, 2.Department of Genetic Medicine, University of Fukui Hospital, 3.Department of Pathology, University of Fukui Hospital, 4.Obstetrics and Gynecology, University of Fukui)

[P1-03-4]The characteristics of BRCA deleterious alteration in metastatic castration-resistant prostate cancer-patient

Hideyasu Tsumura1,2, Dai Koguchi2, Naomi Araki1, Rika Kawata1, Keiko Takahashi1, Hironao Shirai1, Masao Araki1, Akiko Itakura1, Yuichiro Iida1, Sachiko Ohori1, Mina Waraya1, Kazumasa Matsumoto2, Takada Fumio1,3 (1.Genetics Division, Department of Genetics, Kitasato University Hospital, 2.Department of Urology, Kitasato University School of Medicine, 3.Department of Medical Genetics and Genomics, Kitasato University Graduate School of Medical Sciences)

[P1-03-5]The status of HRD testing and genetic counseling for advanced ovarian cancer

Sayaka Kawashita1, Yuri Hasegawa1, Riko Matsuda2, Itsuki Kajimura1, Shoko Miura1, Kiyonori Miura1 (1.Department of Obstetrics and Gynecology, Nagasaki University, Japan, 2.Genetic counseling unit of clinical genomics center, Nagasaki university hospital)

[P1-03-6]Germline BRCA1-mutated synchronous and metachronous pancreatic acinar cell carcinoma with long-term survival

Yuzuki Tanaka1, Tomohiro Kubo1, Yuki Ikeda1, Joji Muramatsu1, Ayako Murota2,3, Makoto Usami1, Ginji Omori1, Norito Suzuki1, Akihiro Sakurai2, Kohichi Takada1 (1.Department of Medical Oncology, Sapporo Medical University School of Medicine, 2.Department of Medical Genetics and Genomics, Sapporo Medical University School of Medicine, 3.Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine)

[P1-03-7]The characteristics of image findings and the accuracy for BRCA-positive breast cancer

Kouji Ohta, Tomoko Itoh, Jun Katoh, Ikue Hata, Eisin Takenaka (Department of Clinical Genetics, Fukui Prefectural, Fukui, Japan)

[P1-03-8]Current status of hereditary breast cancer medical treatment at our hospital

Fuminori Aki1, Ippei Kamidi2, Shinzo Ozaki2, Iyo Nakamura2, Misaki Nakaya2, Takanori Kawamura3, Tomohiro Okazoe3 (1.Ito Breast Surgery Clinic,Kochi,Japan, 2.Hosogi Hospital Surgery, 3.Kochi Seikyou Hospital Surgery)

[P1-03-9]Current Status of Hereditary Breast and Ovarian Cancer (HBOC) Management at Our Hospital

Rie Nakamura1, Yoshino Kinjo1, Yukiko Chinen1, Tomoko Nakamoto1, Minako Imamura2, Yasutsugu Chinen2, Koichi Nakanishi2, Masayuki Sekine1 (1.Department of Obstetrics and Gynecology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan, 2.Genetic Counseling Unit, University of the Ryukyus Hospital, Okinawa, Japan)

[P1-03-10]A case report of occult breast cancer detected by CRRM for a patient with HBOC

Naotaka Uchida, Miho Takeshita, Takako Suda (Department of Breast and Endocrine Surgery, Matsue City Hospital, Matsue, Japan)

[P1-03-11]Summary of microsatellite instability test results and genetic counseling for MSI-H cases in our hospital

Nobutaka Hayashi, Nanako Omichi, Sayaka Takabuchi, Hisateru Yasui (Kobe City Medical Center General Hospital, Hyogo, Japan)

[P1-03-12]MSI testing as assistance in selecting adjuvant chemotherapy and genetic insights for stage II/III colorectal cancer

Serina Sasaki1, Kentaro Kawakami2,3, Chiaki Takada1, Yumi Takahashi1, Kei Onodera2, Sosuke Sumikawa4, Kuniaki Sasaki4, Takaya Kusumi4, Aki Ishikawa5, Hiroyuki Okuda2 (1.Department of Nursing, Keiyukai Sapporo Hospital,Japan, 2.Department of Medical Oncology, Keiyukai Sapporo Hospital,Japan, 3.Kawakami Clinic of Internal Medicine,Japan, 4.Department of Gastroenterological Surgery, Keiyukai Sapporo hospital, Japan, 5.Department of Medical Genetics and Genomics, Sapporo Medical University School of Medicine, Japan)

[P1-03-13]Analysis of germline variants in homologous recombination repair genes in Japanese patients with biliary tract cancer

Yoichi Furukawa1, Kiyoko Takane1, Kiyoshi Yamaguchi1, Tsuneo Ikenoue1, Koichi Matsuda1,2 (1.The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 2.Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan)

[P1-03-14]The Utility of Multigene Panels in Germline Profiling and the Role of the Germline Board in MONSTAR-2 and BRANCH Studies

Miki Aitani1, Manami Matsukawa2, Chikako Tomozawa2, Kaori Kimura1, Yumie Hiraoka1, Yu Komura1, Mitsuho Imai1, Riu Yamashita3, Takao Fujisawa1, Makoto Hirata2, Issei Imoto4, Shinji Kosugi5, Yoshino Takayuki1, Yoshiaki Nakamura1, Takeshi Kuwata1 (1.National Cancer Center Hospital East, 2.National Cancer Center Hospital, 3.Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 4.Aichi Cancer Center Research Institute, 5.Kyoto University Graduate School of Medicine)

[P1-03-15]Utility and feasibility of cancer genome profiling tests for gynecological cancer

Ayaka Saito1, Akira Hirasawa2,3, Maki Tanioka4, Kanako Tsukamoto1, Mizuki Takano1, Kazuyo Kiribayashi1, Kako Kuroiwa1, Rioko Iida1, Yurie Sato1, Orie Kobayashi1, Kazuya Tamura1, Satoshi Umezawa1 (1.Department of Obstetrics and Gynecology, Japanese Red Cross Musashino Hospital, Tokyo, Japan, 2.Department of Clinical Genomic Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan, 3.Department of Surgery, Japanese Red Cross Musashino Hospital, Tokyo, Japan, 4.Medical AI project, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan)

[P1-03-16]The presumed germline pathogenic variants from the Comprehensive Genomic Profiling Test on the prostate cancer

Tomoko Sahara1, Maho Kuroda1, Ikuno Kawabata1,3, Masafumi Toyoshima1,3, Hidehiko Miyake1,4, Kei Uehara1,2, Hiroshi Yoshida2, Takeshi Yamada1,2 (1.Division of Clinical Genetics, Nippon Medical School Hospital, 2.Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School Hospital, 3.Department of Obstetrics and Gynecology, Nippon Medical School Hospital, 4.Department of Genetic Counseling, Graduate School of Humanities and Science, Ochanomizu University)

[P1-03-17]Current Status of Disclosure of Secondary Findings of Comprehensive Cancer Genome Profiling (CGP) Test at Our Hospital

Shigenori Wakita1, Mami Kaneko1, Takayoshi Kawabata1, Yosuke Kito2, Takashi Sone2, Kunihiro Tsuji2, Atsushi Nohara1 (1.Department of Clinical Genetics, Ishikawa Prefectural Central Hospital, Ishikawa, Japan, 2.Department of Medical Oncology, Ishikawa Prefectural Central Hospital)

[P1-03-18]Current Status and Issues of Genomic Profiling Testing for Gynecological Cancer in Our Hospital

Naofumi Yamane1,2, Iemasa Koh1, Tomomi Yamazaki1, Katsuyuki Tomono1, Yurika Mukai1, Kouji Banno1, Yoshiki Kudo1, Hikaru Nakahara2, Hiroaki Niitsu2, Takao Hinoi2 (1.Department of Obstetrics and gynecology, Hiroshima University Hospital, Hiroshima, Japan, 2.Department of Medical Genetics and Genomics, Hiroshima University Hospital, Hiroshima, Japan)

[P1-03-19]Cancer Gene Panel Testing System among Facilities with Genetic Counseling partnership

Hisayo Fukushima1, Eiko Hirokawa3, Akiko Yanagi3, Takao Takahashi2,3 (1.Department of Cancer Clinical Genetics, Saitama Medical University International Medical Center, 2.Department of Supportive Care Medicine, Saitama Medical University International Medical Center, 3.Maruyama Memorial General Hospital)

[P1-03-20]Current status and issues of outpatient genetics at regional core hospitals

Kozue Yoshida1, Naoto Takase2 (1.Department of Cancer treatment support center,Takarazuka City Hospital,Hyogo,Japan, 2.Department of Oncology/Respiratory Medicine,Takarazuka City Hospital,Hyogo,Japan)

[P1-03-21]Transcriptome Analysis of HBV-related Hepatocellular Carcinoma Using Long-Read Sequencing

Ko Ikemoto1, Arisa Igarashi1, Wittawin Worakitchanon1, Pyae Aye Chan1, Fangling Fan1, Hidewaki Nakagawa2, Nao Nishida3, Masashi Mizokami3, Katsushi Tokunaga4, Akihiro Fujimoto1 (1.Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2.Center for Integrative Medical Sciences, Riken, 3.Genome Medical Science Project, National Center for Global Health and Medicine, 4.Genome Medical Science Project-Toyama, National Center for Global Health and Medicine)

[P1-03-22]Transcriptome analysis of adult T-cell leukemia using long-read sequencing technology

Ryoji Kuribayashi1, Azusa Tanaka1, Motoko Unoki1, Junichiro Yasunaga2, Masao Matsuoka2,3, Akihiro Fujimoto1 (1.Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2.Faculty of Life Sciences, Kumamoto University, 3.Kumamoto Rosai Hospital)

[P1-03-23]Exploration of Cancer Driver Genes Using Three Dimensional Protein Structures

Miku Soeda, Akihiro Fujimoto, Motoko Unoki (Department of Human Genetics, School of International Health, Graduate School of Medicine, The University of Tokyo)

[P1-03-24]The current status and challenges of germline multi-gene panel testing for pheochromocytoma and paraganglioma

Masato Yonamine1,2, Kazuhiro Takekoshi2 (1.Doctoral program in Medical Sciences, Graduate School of Comprehensive Human Sciences University of Tsukuba, Ibaraki, Japan, 2.Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan)

[P1-03-25]The regulation of CD47 expression in non-small cell lung cancer

Koji Teramoto1,2, Hidetoshi Sumimoto1,2, Yataro Daigo1,2 (1.Department of Medical Oncology, Shiga University of Medical Science, 2.Cancer Center, Shiga University of Medical Science Hospital)

[P1-03-26]The transcription factor MZF1 activates the promoter of ZEB2, a key regulator of epithelial-mesenchymal transition

Yasuyo Suzuki, Noriko Nomura, Kenichiro Yamada, Shin Hayashi (Department of Genetics, Institute for Developmental Research, Aichi Developmental Disability Center, Aichi, Japan)

[P1-03-27]Genome-wide epigenetic immune profile changes related to oncogenic EGFR signaling in human lung cancer

Hidetoshi Sumimoto1,2, Astushi Takano1,2,3, Kouji Teramoto1,2, Yataro Daigo1,2,3 (1.Department of Medical Oncology, Shiga University of Medical Science, Shiga, Japan, 2.Center for Advanced Medicine against Cancer, Shiga University of Medical Science, 3.Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo)