The 29th Annual Meeting of the Japanese Society for Vaccinology/The 66th Annual Meeting of the Japanese Society of Clinical Virology
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Session Details

Oral DiscussionBasic Vaccinology

Oral Presentation 10 : Basic vaccinology

Sun. Sep 28, 2025 10:45 AM - 11:55 AM JST
Sun. Sep 28, 2025 1:45 AM - 2:55 AM UTC
Room 4(2F Small Hall)
Chair:Masanori Isogawa, Taishi Onodera
10:45 AM - 10:55 AM JST(1:45 AM - 1:55 AM UTC)

[O10-01]SARS-CoV-2交差中和抗体の誘導を阻害するウイルス抗原の構造的要因

*Yu Adachi1, Takashi Sato2, Ryutaro Kotaki1, Saya Moriyama1, Shintaro Oishi1, Takayuki Matsumura1, Masaki Isogawa3, Masaharu Shinkai4, Yoshimasa Takahashi1 (1. Research Center for Vaccine Development, National Institute of Infectious Diseases, Japan Institute for Health Security, 2. Institute for Aqua Regeneration, Shinshu University, 3. Department of Virology II, National Institute of Infectious Diseases, Japan Institute for Health Security, 4. Tokyo Shinagawa Hospital)
10:55 AM - 11:05 AM JST(1:55 AM - 2:05 AM UTC)

[O10-02]Two-year trajectories of SARS-CoV-2 antibody titer decay stratified by vaccination dose count and infection history

*Koki Numakura1,2, Sho Miyamoto2, Haruko Takeyama1, Tadaki Suzuki2 (1. Waseda University, Laboratory of Molecular Engineering for Life , 2. National Institute of Infectious Diseases, Department of Infectious Pathology)
11:05 AM - 11:15 AM JST(2:05 AM - 2:15 AM UTC)

[O10-03]SARS-CoV-2 mRNAワクチン接種マウスにおけるmRNAの血中および組織内局在の解析

*Mami Uemura1, Kou Hiraga1, Sayuri Sakuragi1, Haruka Momose 1, Kiyoko Nojima1, Wakako Kuribayashi1, Mieko Ishii1, Keiko Imai1, Jun-ichi Maeyama1, Emi Ikebe1, Ryo Amano1, Madoka Kuramitsu1, Kenta Tezuka1, Yohei Seki1, Takuo Mizukami1 (1. Research Center for Biological Products in the Next Generation, National Institute of Infectious Diseases, Japan Institute for Health Security)
11:15 AM - 11:25 AM JST(2:15 AM - 2:25 AM UTC)

[O10-04]変異株に対する交叉反応性向上を目的とした構造情報に基づく新規COVID-19ワクチン抗原の設計

*Takuya Hemmi1,2, Saya Moriyama3, Akira Ainai2, Sho Miyamoto2, Satoru Nagatoishi4, Hisano Yajima1, Rin Shirota1, Shiori Ueno2, Kei Asayama2, Kouhei Tsumoto4, Yukihiko Sugita5, Takeshi Noda5, Yoshimasa Takahashi3, Tadaki Suzuki2, Takao Hashiguchi1 (1. Laboratory of Medical virology, Institute for Life and Medical Sciences, Kyoto University, 2. Department of Infectious Disease Pathology, National Institute of Infectious Diseases, Japan Institute for Health Security, 3. Research Center for Vaccine Development, National Institute of Infectious Diseases, Japan Institute for Health Security, 4. Medical Device Development and Regulation Research Center, School of Engineering, The University of Tokyo, 5. Laboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University)
11:25 AM - 11:35 AM JST(2:25 AM - 2:35 AM UTC)

[O10-05]次世代安全性評価法によるモダリティの異なる新型コロナウイルスワクチンの比較

*Kou Hiraga1, Haruka Momose1, Wakako Kuribayashi1, Mami Uemura1, Mieko Ishii1, Keiko Imai1, Junichi Maeyama1, Kenta Tezuka1, Yohei Seki1, Madoka Kuramitsu1, Takuo Mizukami1 (1. Center for Next-Generation Biologics Research, National Institute of Infectious Diseases, Japan Institute for Health Security)
11:35 AM - 11:45 AM JST(2:35 AM - 2:45 AM UTC)

[O10-06]自己増幅型RNAワクチン接種後のヒトにおける持続的抗体応答を予測する記憶B細胞サブセット

*Taishi Onodera Onodera1, Saya Moriyama1, Takuto Nogimori3, Ayae Nishiyama3, Takuya Yamamoto3, Wataru Akahata2, Yoshimasa Takahashi1 (1. Research Center for Vaccine Development, National Institute of Infectious Diseases, Japan Institute for Health Security, 2. VLP Therapeutics Japan, Inc. , 3. Laboratory of Precision Immunology, Center for Intractable Diseases and ImmunoGenomics, National Institutes of Biomedical Innovation, Health and Nutrition)
11:45 AM - 11:55 AM JST(2:45 AM - 2:55 AM UTC)

[O10-07]ヘルパー脂質の至適化による副反応低減型mRNAワクチンの開発

*Tatsuya Karaki1,2, Taro Shimizu1,3,4, Toshiro Hirai1,3,4,5, Hidetaka Akita4,6, Yasuo Yoshioka1,2,3,4,5 (1. RIMD, The Univ. of Osaka, 2. BIKEN, 3. OTRI, The Univ. of Osaka , 4. CAMaD, The Univ. of Osaka, 5. Grad. Sch. Pharm. Sci., The Univ. of Osaka, 6. Grad. Sch. Pharm. Sci., Tohoku Univ.)
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