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Roles of double stranded DNA-strand separation and a RecA-bound DNA helicase in homologous recombination

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The genome, the blueprint of life, is stably maintained through various chromosome processes such as DNA replication, DNA repair, recombination, and also through regulation of chromosome structure. Misregulation of these mechanisms leads to mutations and increased instability of the genome, ultimately causing cancer, aging, and genetic diseases. This symposium will discuss the latest insights into how cells faithfully duplicate its genomic and epigenomic information and how the lesions resulting from its failure would be repaired through recombination and repair pathways to maintain the genome integrity.<br>

The 47th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-12-06]Roles of double stranded DNA-strand separation and a RecA-bound DNA helicase in homologous recombination

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