The 47th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Open-call Symposium : [1AS-12] Genome replication and stable maintenance of genomic information

[1AS-12]【E】Genome replication and stable maintenance of genomic information

Wed. Nov 27, 2024 9:00 AM - 11:15 AM JST
Wed. Nov 27, 2024 12:00 AM - 2:15 AM UTC
Room 12(Fukuoka International Congress Center, 2F 203)
Organizer: Yasunori Noguchi (Kyushu university), Hisao Masai (Tokyo Metropolitan Institute of Medical Science)
The genome, the blueprint of life, is stably maintained through various chromosome processes such as DNA replication, DNA repair, recombination, and also through regulation of chromosome structure. Misregulation of these mechanisms leads to mutations and increased instability of the genome, ultimately causing cancer, aging, and genetic diseases. This symposium will discuss the latest insights into how cells faithfully duplicate its genomic and epigenomic information and how the lesions resulting from its failure would be repaired through recombination and repair pathways to maintain the genome integrity.
9:00 AM - 9:02 AM JST(12:00 AM - 12:02 AM UTC)

Introduction

9:02 AM - 9:18 AM JST(12:02 AM - 12:18 AM UTC)

[1AS-12-01]Novel links of regulatory systems for chromosomal replication initiation with transcription and translation in E. coli

Kazutoshi Kasho1, Wataru Nakagaki1, Ryuji Sakai1, Kosuke Ito1, Rion Satomura1, Takafumi Jinnouchi1, Shogo Ozaki1, ○Tsutomu Katayama1 (1. Kyushu Univ., Grad. Sch. Parm. Sci.)
Comment()
9:18 AM - 9:34 AM JST(12:18 AM - 12:34 AM UTC)

[1AS-12-02]Biochemical investigation of the mechanism of human DNA replication initiation

○Yasunori Noguchi1, Yugo Zaizen1, Kaname Saito1, Christian Speck2, Masatoshi Fujita1 (1. Grad. Sch. Pharm. Sci., Kyushu Univ., 2. Imperial College London)
Comment()
9:34 AM - 9:46 AM JST(12:34 AM - 12:46 AM UTC)

[1AS-12-03(1P-016)]Differential DNA methylation controls asynchronous DNA replication at imprinted chromosomal domains

○Yui IMAIZUMI1, François Charon3, Benoît Moindrot3, Daan Noordermeer3, Jean-Charles Cadoret4, Robert Feil1,2 (1. Institut de Génétique Moléculaire de Montpellier, 2. University of Montpellier, 3. University of Paris-Saclay, 4. Institut Jacques Monod)
Comment()
9:46 AM - 9:58 AM JST(12:46 AM - 12:58 AM UTC)

[1AS-12-04(1P-062)]Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10

○Masateru Takahashi1, Yujing Ouyang1, Amani Al-Amodi1, Muhammad Tehseen1, Lubna Alhudhali1, Afnan Shirbini1, Vlad-Stefan Raducanu1, Gang Yi1, Ammar Usman Danazumi1, Alfredo De Biasio1, Samir M Hamdan1 (1. King Abdullah University of Science and Technology)
Comment()
9:58 AM - 10:14 AM JST(12:58 AM - 1:14 AM UTC)

[1AS-12-05]Novel roles of Claspin/Mrc1 in stress responses and epigenetic regulation

○Hisao Masai1, Chi-Chung Yang1, Sebastian Charlton2, Yutaka Kanoh1, Haowen Hsiao1, Zhiying You1, Genevieve Thon2 (1. Tokyo Metropolitan Institute of Medical Science, 2. Department of Biology, University of Copenhagen, Copenhage)
Comment()
10:14 AM - 10:30 AM JST(1:14 AM - 1:30 AM UTC)

[1AS-12-06]Roles of double stranded DNA-strand separation and a RecA-bound DNA helicase in homologous recombination

○Takehiko Shibata1 (1. Tokyo Metropolitan Institute of Medical Science)
Comment()
10:30 AM - 10:46 AM JST(1:30 AM - 1:46 AM UTC)

[1AS-12-07]Dynamic structures and functions of enzymes working in DNA double-strand break repair

○Asako Furukohri1 (1. Osaka university)
Comment()
10:46 AM - 10:58 AM JST(1:46 AM - 1:58 AM UTC)

[1AS-12-08(1P-081)]Rad54 prevents excessive intergenerational Rad51 aggregation in fission yeast

Goki Taniguchi1, Alexander I May1, Hiroshi Iwasaki1, ○Hideo Tsubouchi1 (1. Tokyo Institute of Technology)
Comment()
10:58 AM - 11:14 AM JST(1:58 AM - 2:14 AM UTC)

[1AS-12-09]Novel protein networks involving ARID1A and ARID1B in SWI/SNF complex, and its functions in genome stability

Shin-ichiro Kanno1, Takayasu Kobayashi1, Reiko Watanabe2, Akihiro Kurimasa3, Ryutaro Shirakawa1, Akira Yasui1, ○Ayako Ui1 (1. Tohoku University, 2. Osaka University, 3. Tohoku Medical and Pharmaceutical University)
Comment()
11:14 AM - 11:15 AM JST(2:14 AM - 2:15 AM UTC)

Conclusion

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