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Allelic asymmetry in mammalian zygotes

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In textbooks, eukaryotic cells have a single nucleus. However, there are a number of cells with multiple nuclei, such as macro- and micro-nuclei in ciliates, multinuclei in hepatocytes and muscle cells, maternal and paternal pronuclei in fertilized oocytes, and micronuclei in cancer cells. Why do these cells have multiple nuclei? This is an important question related to nuclear functions and reprogramming. In this workshop, we will introduce the unique biological questions faced by researchers working with multinuclear cells and discuss the regulation of nuclear and chromatin functions.<br>

The 47th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-13-01]Allelic asymmetry in mammalian zygotes

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