Session Details
[1AS-13]【J】Biology of multinuclear cells
Wed. Nov 27, 2024 9:00 AM - 11:15 AM JST
Wed. Nov 27, 2024 12:00 AM - 2:15 AM UTC
Wed. Nov 27, 2024 12:00 AM - 2:15 AM UTC
Room 13(Fukuoka International Congress Center, 2F 204)
Organizer: Azusa Inoue (RIKEN), Tokuko Haraguchi (Osaka University)
In textbooks, eukaryotic cells have a single nucleus. However, there are a number of cells with multiple nuclei, such as macro- and micro-nuclei in ciliates, multinuclei in hepatocytes and muscle cells, maternal and paternal pronuclei in fertilized oocytes, and micronuclei in cancer cells. Why do these cells have multiple nuclei? This is an important question related to nuclear functions and reprogramming. In this workshop, we will introduce the unique biological questions faced by researchers working with multinuclear cells and discuss the regulation of nuclear and chromatin functions.
Introduction
[1AS-13-02]Why does a fertilized egg need to form two pronuclei?
○Hirohisa Kyogoku1 (1. Kobe university)
[1AS-13-03]Significant dynamics of the nuclear pore complexes during nuclear fate determination in the ciliate Tetrahymena
○Masaaki Iwamoto1 (1. Nihon Univ.)
[1AS-13-04(1P-345)]Understanding Micronuclei with Importin-α Enrichment
○Yoichi Miyamoto1, Shige H. Yoshimura2, Mutsumi Yokota3, Masato Koike3, Masahiro Oka4, Hisato Saitoh5, Toyomasa Katagiri1 (1. Lab. Biofunc. Mol. Med., Nat. Inst. Biomed. Innov., Health and Nutr., 2. Grad. Sch. Biostudies, Kyoto Univ., 3. Dept. Cell Biol. Neurosci., Grad. Sch. Med., Juntendo Univ., 4. Dept. Reg. Infect. Cancer, Res. Inst. Micrb. Dis., Osaka Univ. , 5. Faculty Adv. Sci. Tech. (FAST), Kumamoto Univ.)
[1AS-13-05]The significance of hepatocyte polyploidization in response to genomic damage
○Tomonori Matsumoto1 (1. Osaka Univ.)
[1AS-13-06]Behavior of multinuclear cells induced by cell fusion
Taisei Kumazaki1, Joey Nakane2, Chinatsu Yonekawa1, ○Tomomi Tsubouchi1,2 (1. NIBB, 2. SOKENDAI)
[1AS-13-07]Problems with multinucleated cells revealed by attempts to create artificial nuclei in living cells
○Tokuko Haraguchi1, Nao Yonezawa2, Yasushi Hiraoka1, Kazuo Yamagata2 (1. Osaka Univ., 2. Kindai Univ.)