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Altered regulation of transcription and retrotransposition of LINE-1 in the brain and psychiatric disorders

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SINEs and LINEs are retrotransposon-associated sequences that occupy a large part of the mammalian genome, and show distinct and mutually exclusive distribution patterns. SINE mediated recruitment of CTCF and LINE RNA mediated liquid-liquid phase separation (LLPS) may promote 3D organization of the genome. By proposing that transposable elements constitute a new code (transposable elements code: TEC) to regulate higher order regulation and function of the genome, in this workshop we will introduce latest research on transposable elements, and 3D regulation of the genome.<br>

The 47th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-17-07]Altered regulation of transcription and retrotransposition of LINE-1 in the brain and psychiatric disorders

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