Session Details

[1AS-17]【J】Higher order genome regulation and function mediated by the transposable element code (TEC)

Wed. Nov 27, 2024 9:00 AM - 11:15 AM JST
Wed. Nov 27, 2024 12:00 AM - 2:15 AM UTC
Room 17(Marine Messe Fukuoka Hall B, 2F Meeting Room 2-2)
Organizer: Emi Hibino (Nagoya University), Kenji Ichiyanagi (Nagoya University)
SINEs and LINEs are retrotransposon-associated sequences that occupy a large part of the mammalian genome, and show distinct and mutually exclusive distribution patterns. SINE mediated recruitment of CTCF and LINE RNA mediated liquid-liquid phase separation (LLPS) may promote 3D organization of the genome. By proposing that transposable elements constitute a new code (transposable elements code: TEC) to regulate higher order regulation and function of the genome, in this workshop we will introduce latest research on transposable elements, and 3D regulation of the genome.

Introduction

[1AS-17-01]Dynamic structure analysis of histone tails in nucleosome by solution NMR

○Ayako Furukawa1,2, Masatoshi Wakamori3, Yasuhiro Arimura4, Hideaki Ohtomo2, Yasuo Tsunaka2, Hitoshi Kurumizaka4, Takashi Umehara3, Yoshifumi Nishimura2 (1. Kyoto University, 2. Grad. Sch. Integr. Sci. Life, Hiroshima Univ., 3. BDR, RIKEN, 4. IQB, Univ. of Tokyo)
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[1AS-17-02]In-cell NMR study on structure, dynamics, and ligand interactions of nucleic acids in living human cells

○Yudai Yamaoki1,2, Takashi Nagata1,2, Keiko Kondo1, Tomoki Sakamoto1, Omar Eladl1,2, Masato Katahira1,2 (1. Inst. Adv. Energy, Kyoto Univ., 2. Grad. Sch. Energy Sci., Kyoto Univ.)
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[1AS-17-03(1P-101)]Role of transposable elements to link 3D genome organization with DNA replication timing

○SHARIF Jafar1, KOSEKI Haruhiko1 (1. IMS Yokohama RIKEN)
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[1AS-17-04(1P-107)]Sequence-specific anti-silencing mechanism regulated by transposon-derived protein VANC

○Akihisa Osakabe1, Yusaku Tanaka1, Raku Saito2, Hisato Hirano1, Wataru Shihoya1, Yuzuru Ito1, Osamu Nureki1, Tetsuji Kakutani1 (1. Biol. Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo)
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[1AS-17-05]Transcriptional regulation of intragenic transposons in plant genomes

○Hidetoshi Saze1 (1. Okinawa Institute of Science and Technology Graduate University)
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[1AS-17-06]Functions of large-scaled microRNA cluster derived from retrotransposon and their aberrations observed in nuclear transferred mice

○Kimiko Inoue1 (1. Bioresource Research Center, RIKEN)
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[1AS-17-07]Altered regulation of transcription and retrotransposition of LINE-1 in the brain and psychiatric disorders

○Kazuya Iwamoto1 (1. Department of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University)
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[1AS-17-08(1P-096)]Distinctive regulation of transposable elements in the human brain

○Risa Watanabe1, Cyril J Peter1, Bicheng Jiang1, Foramben Patel1, Travis Dawson1, Aman Agarwal1, Will Lounsbery-Scaife1, Maya Fridrihk1, Kiran Girdhar1, Panos Roussos1,2, Ashok Patowary3, Sathiji Nageshwaran3, Nadejda Tsankova1, Hyejung Won4, Robert Sebra1, Benjamin Chen1, Dan Hasson1, Schahram Akbarian1 (1. Icahn School of Medicine at Mount Sinai, 2. James J. Peters VA Medical Center, 3. University of California Los Angeles, 4. University of North Carolina at Chapel Hill)
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Conclusion