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Tue. Nov 26, 2024

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One-step generation of spatiotemporal gene-editing mice by transposon-dependent gRNA delivery.

In the context of elucidating the molecular mechanisms underlying human development, regeneration, and repair, as well as understanding the pathophysiology of diseases for drug discovery and therapeutic development, genetic modification in mouse models plays a crucial role. This symposium will present and discuss cutting-edge technologies, such as the combination of CRISPR/Cas9, transposon systems and artificial chromosomes for spatiotemporal editing of multiple genes in mice and the development of reporter mouse systems. These advancements are expected to unveil novel molecular and biological insights for the first time, contributing to the ongoing discourse in the field.<br>

【J】Developing and Applying Innovative Next-Generation Gene Editing Techniques for Mouse Model Generation

The 47th Annual Meeting of the Molecular Biology Society of Japan

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[2MS-13-03]One-step generation of spatiotemporal gene-editing mice by transposon-dependent gRNA delivery.

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