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Generation of the organotypic kidney structure solely from pluripotent stem cells

Co-hosted by: Japanese Society of Nephrology

The kidney not only functions as an excretory organ, but also plays a central role in maintaining homeostasis as a metabolic and endocrine organ. However, tissue damages that progress beyond a point of no-return due to chronic inflammation and fibrosis are irreversible. Additionally, because of the structural and physiological complexity, basic researchers have difficulty in joining the research community, and indeed the kidney is one of the most difficult organs to regenerate. Nevertheless, a multiomics approach at a single cell level or temporal and spatial regulation of molecules of interest within an experimental animal, are greatly deepening our understanding of kidney molecular biology.<br>

The 47th Annual Meeting of the Molecular Biology Society of Japan

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[3PS-04-02(3P-552)]Generation of the organotypic kidney structure solely from pluripotent stem cells

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