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Yeast possess independently regulated TORC1 pools in vacuoles and mitochondria

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TOR kinase forms two independent complexes, TOR complex 1 (TORC1) and TOR complex 2 (TORC2), which sense and integrate growth-related signals such as nutrients, growth factors, and stress, and regulate cell metabolism. Therefore, TOR is not only involved in the regulation of a wide range of physiological functions, but also its dysfunction is the basis of various pathological phenomena. In this symposium, we would like to share the latest research results and future prospects, ranging from attempts to elucidate the regulatory mechanisms and physiological functions of TOR using various model organisms to protein design of TOR and clinical applications of the TOR inhibitor rapamycin.<br>

The 47th Annual Meeting of the Molecular Biology Society of Japan

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[3PS-17-01]Yeast possess independently regulated TORC1 pools in vacuoles and mitochondria

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