The 47th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Open-call Symposium : [3PS-17] The TOR signaling - Toward a comprehensive understanding

[3PS-17]【J】The TOR signaling - Toward a comprehensive understanding

Fri. Nov 29, 2024 4:45 PM - 7:00 PM JST
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Room 17(Marine Messe Fukuoka Hall B, 2F Meeting Room 2-2)
Organizer: Mirai Tanigawa (Hamamatsu University School of Medicine), Hirokazu Nakatsumi (Nagoya City University)
TOR kinase forms two independent complexes, TOR complex 1 (TORC1) and TOR complex 2 (TORC2), which sense and integrate growth-related signals such as nutrients, growth factors, and stress, and regulate cell metabolism. Therefore, TOR is not only involved in the regulation of a wide range of physiological functions, but also its dysfunction is the basis of various pathological phenomena. In this symposium, we would like to share the latest research results and future prospects, ranging from attempts to elucidate the regulatory mechanisms and physiological functions of TOR using various model organisms to protein design of TOR and clinical applications of the TOR inhibitor rapamycin.
4:45 PM - 4:47 PM JST(7:45 AM - 7:47 AM UTC)

Introduction

4:47 PM - 5:05 PM JST(7:47 AM - 8:05 AM UTC)

[3PS-17-01]Yeast possess independently regulated TORC1 pools in vacuoles and mitochondria

○Mirai Tanigawa1, Yumi Yamahama1, Mina Toyamna1, Satoshi Okada2, Tatsuya Maeda1 (1. Hamamatsu University School of Medicine, 2. Kyushu University)
Comment()
5:05 PM - 5:24 PM JST(8:05 AM - 8:24 AM UTC)

[3PS-17-02]Elucidation of the Physiological Functions and TORC1 Pathway Regulation of Ammonium Transporters in Schizosaccharomyces pombe

○Yukiko Nakase1, Ng Shet Lee1, Yuichi Morozumi1, Ayu Shibatani1, Takeru Yomogita1, Daisuke Watanabe1, Hiroshi Takagi1, Kazuhiro Shiozaki1,2 (1. Nara Institute of Science and Technology, 2. University of California, Davis)
Comment()
5:24 PM - 5:44 PM JST(8:24 AM - 8:44 AM UTC)

[3PS-17-03]Whole-genome CRISPR screenings to identify a novel regulator of mTORC1 signaling

○Mitsugu Shimobayashi1 (1. KU Leuven)
Comment()
5:44 PM - 6:00 PM JST(8:44 AM - 9:00 AM UTC)

[3PS-17-04(3P-459)]Development of chemogenetic tools for temporal control of mTORC1 activity in living cells

○Naoki Komatsu1, Atsushi Miyawaki1,2 (1. RIKEN CBS, 2. RIKEN RAP)
Comment()
6:00 PM - 6:20 PM JST(9:00 AM - 9:20 AM UTC)

[3PS-17-05]Toward understanding roles of yeast TOR complexes by structure-based rational engineering approach

○Takahiro Kosugi1,2,3 (1. Institute for Molecular Science (IMS), National Institutes of Natural Scienc es (NINS), 2. SOKENDAI (The Graduate University for Advanced Studies), 3. PRESTO, Japan Science and Technology Agency (JST))
Comment()
6:20 PM - 6:39 PM JST(9:20 AM - 9:39 AM UTC)

[3PS-17-06]mTORC1 regulation of growth and lifespan through RNA splicing in response to nutrients

○Takafumi Ogawa1, T. Keith Blackwell2, Masaki Mizunuma1 (1. Hiroshima Univ., 2. Harvard Med. Sch.)
Comment()
6:39 PM - 6:59 PM JST(9:39 AM - 9:59 AM UTC)

[3PS-17-07]TOR inhibitor for intractable vascular anomalies

○Michio Ozeki1 (1. Gifu University Hospital)
Comment()
6:59 PM - 7:00 PM JST(9:59 AM - 10:00 AM UTC)

Conclusion

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