Session Details
[1P-2]Poster Presentation
Wed. Nov 27, 2024 12:55 PM - 2:55 PM JST
Wed. Nov 27, 2024 3:55 AM - 5:55 AM UTC
Wed. Nov 27, 2024 3:55 AM - 5:55 AM UTC
Poster & Exhibition Venue 2 (Marine Messe Fukuoka Hall B, 1F)
3. Development and Regeneration
- a. Organogenesis / Morphogenesis / Regeneration
- b. Stem Cell
- c. Cell Differentiation
- d. Early Development
- e. Reproduction
- f. Others
4. Animal and Plant Physiology, and Diseases
- a. Symbiotic Microorganism
- b. Biological Rhythm
- c. Brain / Nervous System / Neurodevelopment / Structure
- d. Brain / Nervous System / Behavior
- e. Brain / Nervous System / Disorder
- f. Immunity
- g. Infection / Virus
- h. Aging
- i. Cancer Cell
- j. Cancer Tissue / Cancer Therapeutics
- k. Metabolism / Nutrition
- l. Genetic Disorder
- m. Plant
- n. Macrobiology
- o. Others
- a. Organogenesis / Morphogenesis / Regeneration
- b. Stem Cell
- c. Cell Differentiation
- d. Early Development
- e. Reproduction
- f. Others
4. Animal and Plant Physiology, and Diseases
- a. Symbiotic Microorganism
- b. Biological Rhythm
- c. Brain / Nervous System / Neurodevelopment / Structure
- d. Brain / Nervous System / Behavior
- e. Brain / Nervous System / Disorder
- f. Immunity
- g. Infection / Virus
- h. Aging
- i. Cancer Cell
- j. Cancer Tissue / Cancer Therapeutics
- k. Metabolism / Nutrition
- l. Genetic Disorder
- m. Plant
- n. Macrobiology
- o. Others
[1P-529]A causal association between myosin-induces chiral rotation of F-actin in vitro and left-right asymmetric organogenesis in vivo
○Yui Akano1, Asuka Yamaguchi1, Ginjiro Endo1, Utsunomiya Sosuke1, Kohei Yoshimura2, Takeshi Haraguchi2, Kohji Ito2, Kenji Matsuno1 (1. Osaka Univ., 2. Chiba Univ.)
[1P-530]Polycomb Repressive Complex 1 Components in heart development: Insights from Blastocyst Complementation
○Saki Ichikawa1, Kazunori Hojo1, Hiroki Sugishita1,2, Yukiko Gotoh1,2 (1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2. International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo)
[1P-531]Morphological analyses of Wolffian duct differentiation in male mice
○Masayo Harada1, Georgena Djameh1, Tomoko Kitabata1, Keiichi Akita1 (1. Tokyo Medical and Dental University)
[1P-532]Transplantation treatment of rat femoral defects using 3D-printed vascularized tissue engineering bone tissue.
○LO YUCHIH1, Chu TzuHui 2, Shyu JiaFwu2 (1. Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, 2. Department of Biology & Anatomy, National Defense Medical Center, Taipei, Taiwan)
[1P-533]Cadherin-6 controls radial migration of neurons during neocortical development via an integrin-mediated manner
○Yuki Hirota1, Rikaho Saito1, Takao Honda1,2, Hitomi Sano1,3, Kazunori Nakajima1 (1. Keio Univ., 2. Gifu Pharmaceutical Univ., 3. Tokyo Online Univ.)
[1P-534]Decorin is involved in endothelial-to-hematopoietic transition
○Misaki Nakamura1, Maria Shibata-Kanno1, Yuki Sato1 (1. Kyushu University)
[1P-535]The function of the heme transporter FLVCR in echinoderms was choline transport
○Daigo Takemoto1, Kaichi Watanabe1, Yutaro Misawa1, Naoaki Sakamoto1, Akinori Awazu1 (1. Graduate School of Integrated Sciences for Life)
[1P-536]single myofiber culture method : Establishment of a platform for novel skeletal muscle analysis
○Okino Ryosuke1, Fujimaki Shin2, Ono Yusuke1,2 (1. Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2. Kumamoto Univ.)
[1P-537]Functional analysis of BCL11A using zebrafish
○Yuta Sato1,2, Hiroki Maeda1,3, Makoto Kashima4, Makoto Kobayashi1 (1. Inst. of Med., Univ. of Tsukuba, 2. Dept. of Med., Univ. of Tsukuba, 3. M. Prog. in Med. Sci., Univ. of Tsukuba, 4. Dept. of Biomol. Sci., Fac. of Sci., Toho Univ.)
[1P-538]Screening of the factors that are involved in the branching morphogenesis of the external gills in the urodelan Pleurodeles waltl larvae.
○Emiri Nakagawa1, Tamaki Momoi3, Mika Kin3, Kotomi Imura3, Ryuji Toyoizumi1,2 (1. Dept. Biol. Sci., Fac. Sci. Kanagawa University., 2. Res. Inst. for Integr. Sci., Kanagawa University., 3. Grad. Sch. Sci., Kanagawa Univ.)
[1P-539]Understanding mechanisms of scale development and regeneration using goldfish scale morphology mutants
○Saori Matsumoto1, Rui Tang1, Soichiro Fushiki1, Kazuki Muramiya2, Atsushi Nagano3, Hideki Noguchi4, Atsushi Toyoda5, Yoshihiro Omori1,6 (1. Laboratory of Functional Genomics, Graduate School of Bioscience, Nagahama Institute of Bioscience and Technology, 2. Yatomi Station, Aichi Fisheries Res. Inst. , 3. Dept. of Agriculture, Ryukoku Univ., 4. Joint Support Center for Data Science Research (ROIS-DS) , 5. Advanced Genomics Center, National Inst. of Genetics, 6. Grad. Sch. of Integrated Sciences for Life,)
[1P-540]Histone methyltransferase G9a regulates tendon formation in mice
○Hisashi Ideno1, Satoshi Wada2,3, Kazuhisa Nakashima1, Koichiro Komatsu1, Makoto Tachibana4, Akira Nifuji1 (1. Department of Pharmacology, School of Dental Medicine, Tsurumi University, 2. Department of Oral and Maxillofacial Surgery, School of Medicine, Kanazawa Medical University, 3. Department of Orthodontics, School of Dental Medicine, Tsurumi University, 4. Graduate School of Frontier Biosciences, Osaka University)
[1P-541(1MS-06-04)]3D point cloud analysis of multicellular systems
○Yuichi Wada1,2, Minoru Takasato3, Yuri Saito1,2, Etsuo A. Susaki1,2,3,4,5 (1. Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine, 2. Nakatani Biomedical Spatialomics Hub, Juntendo University Graduate School of Medicine, 3. Laboratory for Human Organogenesis, RIKEN Center for Biosystems Dynamics Research, 4. Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 5. RIKEN Center for Biosystems Dynamics Research)
[1P-542]Unraveling New Iron Metabolism Biology through 'Organogenesis—The Iron Atlas'
○Shoko Sashiyama1,2, Ayato Maeda1,2, Akihiro Nita1,2, Toshiro Moroishi1,2 (1. Department of Molecular and Medical Pharmacology, Faculty of Life Sciences, Kumamoto University, 2. Center for Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University)
[1P-543]Molecular analysis of the posterior extension behavior of Scaptodrosophila larvae
○Masaya Takahashi1, Teruyuki Matsunaga1, Akinao Nose1,2 (1. Dept Complex Sci & Engn, Grad Sch Frontier Sci, Univ Tokyo, 2. Dept Phys, Grad Sch Sci, Univ Tokyo)
[1P-544]Functional analysis of Wnt ligands during Xenopus tail regeneration
○Tatsuya Kyoda1, Makoto Nakamura1, Yuka Moriyama1, Ryota Koike1, Ryutaro Nishijima1, Hitoshi Yoshida2, Kimiko Takebayashi1, Atsushi Suzuki1 (1. Amphibian Research Center, Grad. Sch. of Integ. Sci. Life., Hiroshima Univ., 2. National Xenopus Resource, USA)
[1P-546]Nano-scale construction of sensory organs by cell-specific compartmentalized extracellular matrices
○Yuki Itakura1, Housei Wada1, Zhengkuan Sun1,2, Sachi Inagaki1, Shigeo Hayashi1,2 (1. RIKEN, 2. Kobe Univ.)
[1P-547]Elucidation of epithelial inflammation mechanisms using intestinal epithelial organoid
○Masayuki Kono1,2, Rei Kawashima1,2, Shun Tamaki1,2, Tatsunori Maekawa1,2, Takafumi Ichikawa1,2 (1. Dept. of Regulation Biochem., Grad. Sch. of Med. Sci., Univ. of kiasato, 2. Dept. of Biochem., Sch. of Allied Health Sciences, Univ. of Kitasato)
[1P-548]Cell-intrinsic compliance mechanism enables release of tensile stress to prevent tissue rupture
○Chun Wai Kwan1, Shunta Sakaguchi1,2,3, Michiko Takeda1, Takefumi Kondo1,2, Yu-Chiun Wang1 (1. RIKEN Center for Biosystems Dynamics Research , 2. Graduate School of Biostudies, Kyoto University, 3. Graduate School of Integrated Sciences for Life, Hiroshima University)
[1P-549]Deciphering the temporal control of mechanosensing during development
○Mari Yoshida1, Jesús M López-Gay 1, Yohanns Bellaïche1 (1. UMR3215/U934, Institut Curie, FRANCE)
[1P-550]Attempt to establish site-specific transgenic Xenopus tropicalis for macrophage research.
○Hayato Oku1, Haruki Ochi2, Akimasa Fukui1 (1. Chuo Univ, 2. Yamagata Univ)
[1P-551]Co-culture of fibroblasts with endothelial cells and mesenchymal stem cells for periodontal tissue regeneration
○Shunsuke Usui1, Michiyo Honda1 (1. Graduate School of Science and Technology, Meiji University)
[1P-552]Localization of Csf1r-positive cells in skin regeneration of Xenopus tropicalis
○Yuka Hiroaki1, Reika Wada1, Akimasa Fukui1 (1. Chuo University)
[1P-553]Rallyist: a package to facilitate pseudotime analysis in bulk RNA-Seq.
○Yuta Suzuki1, Miho Hosaka2, Makoto Kashima1 (1. Toho University, 2. Aoyama Gakuin University)
[1P-554]Cell lineage analysis of CD73-positive cells in the cartilage
○Marina Sanaki-Matsumiya1, Nao Hosomi1, Hiromi Yanagisawa1, Kenichi Kimura1 (1. University of Tsukuba)
[1P-555]The Bowen-Conradi syndrome protein, EMG1 regulates beta-catenin-dependent epidermalization with GRHL3.
○Chiharu Kimura-Yoshida1, Kyoko Mochida1, Isao Matsuo1 (1. Dept. of Molecular Embryology, Reserach Inst. for MCH.)
[1P-556]Engineering Epithelial Layer Structure Based on Cell-Cell Boundary Tension in a 3D Vertex Model
○Chayanit Thiticharoentam1, Satoru Okuda2 (1. Division of Nano Life Science, Kanazawa University , 2. WPI Nano Life Science Institute, Kanazawa University)
[1P-557]Heterocercal to homocercal transition of teleost caudal fin by hox genes
○SAE OIKAWA1, Rina Koita1, Taisei Tani1, Akiteru Maeno2, Urara Adachi1, Atsuki Ishizu1, Norimasa Iwanami3, Masaru Matsuda3, Akinori Kawamura1 (1. Grad. sch. of Sci., and Eng., Saitama Univ., 2. National Institute of Genetics, 3. Center for Bioscience Research and Education, Utsunomiya univ.)
[1P-558]Analysis of the maturation state of rat lung epithelial cells in mouse←rat interspecies chimeras
○Yamato Murata1, Syunsuke Yuri3, Masahito Ikawa2, Ayako Isotani1 (1. NAIST, 2. Osaka Univ, 3. NCGG)
[1P-559]The rat-derived heart generated in mice via blastocyst complementation demonstrates functional limitations in chimera development
○Shunsuke Yuri1,2, Norie Arisawa2, Ayako Isotani2 (1. National Center for Geriatrics and Gerontology (NCGG), 2. Nara institute of science and technology)
[1P-560]All new CoMBI device allow to construct the 3D imaging system at low-cost.
○Yuki Tajika1 (1. Gunma Prefectural College of Health Science)
[1P-561]Mechanisms of evolutionary acquisition of the bilateral eyes in vertebrates
○Kazuhito Kinemori1, Yusuke Sakaguchi1, Tomoatsu Takano1, Takeshi Igawa1, Nanoka Suzuki1, Makoto Suzuki1, Hajime Ogino1 (1. Hroshima Univ. Amphibian Research Center)
[1P-562]Molecular Basis Underlying the Sternal Diversification in Birds
○Seung June Kwon1, Zhaonan Zou2, Mizuki Honda2, Shinya Oki2, Yuji Atsuta1 (1. Kyushu university, 2. Kyoto university)
[1P-563]Functional analysis of insect cuticle components using ectopic expression systems
○Horie Shuhei1, Tajiri Reiko2 (1. Graduate School of Science and Engineering, Chiba university, 2. Graduate School of Science, Chiba University)
[1P-564]Functional analysis of the neural retina-specific transcription factor Nrl by CRIPR-Cas9 genome editing in medaka Oryzias latipes
○Takahiro Abue1, Shogo Iijima2, Erika Kobayashi1, Yutaka Daido1, Takehiro G. Kusakabe1,2 (1. Grad. Sch. of Nat. Sci., Konan Univ., 2. Dept. of Biol., Fac. of Sci. Engneer., Konan Univ.)
[1P-565]Age-independent transdifferentiation in mouse adult fibroblast by bacterial ribosomes
Anamika Datta1, Arif Istiaq2, ○Kunimasa Ohta1,3 (1. Kyushu Univ. Graduate School of Systems & Life Sciences, 2. Washington Univ. School of Medicine, 3. Kyushu Univ., Faculty of Art & Sciences)
[1P-566]Transdifferentiation of primary chicken muscle-derived cells by ribosomes
○Shota Inoue1, Arif Istiaq2, Anamika Datta1, Mengxue Lu3, Ikko Kawashima3, Kunimasa Ohta1,4 (1. Graduate School of Systems Life Sciences, Kyushu University, 2. Washington University School of Medicine, 3. IntegriCulture, 4. Faculty of Arts and Sciences, Kyushu University)
[1P-567]Exogenous Ribosome Induces Multipotency of HEK293 cells
○FUCHAO TAN1, Anamika Datta1, Arif Istiaq2, Keisuke Yamashita1,3, Kunimasa Ohta1,3 (1. Graduate School of Systems Life Science, Kyushu University, 2. Washington University School of Medicine, 3. Faculty of Arts and Sciences, Kyushu University)
[1P-568]Ribosome induces cell transdifferentiation of mouse neural stem cell
○HAOXUAN GU1, Anamika Datta1, Arif Istiaq3, Keisuke Yamashita1,2, Kunimasa Ohta1,2 (1. KYUSHU University, Graduate School of Systems & Life Sciences, 2. KYUSHU University, Faculty of Arts & Sciences, 3. Washinton University)
[1P-569]A human-specific gene-activating non-coding RNA for EFHC1, an epilepsy-associated gene, functions in the neural stem cell proliferation and cortical structure regulation
○Sota Nishida1, Boyang An1, Arisa Makimura1, Fumihiro Morishita1, Mizuki Honda1, Takuya Imamura1 (1. Hiroshima University, Graduate School of Integrated Sciences for Life)
[1P-570]Mechanistic Analysis of Pluripotency Acquisition during iPSC Production
○ZIWEI JIANG1, Muhammad Hamzah1, Koji Hisatake2, Ken Nishimura2 (1. University of Tsukuba, 2. Lab. Gene Regulation, Instit. Medicine, Univ. Tsukuba)
[1P-571]Dynamics of muscle stem and niche cells in homeostasis, regeneration and pathology
○Shahragim Tajbakhsh1 (1. Stem Cells & Development Unit, Institut Pasteur, Paris, France)
[1P-572]Establishment of preimplantation-type trophoblast stem cells in mice
○Yasuhide Ohinata1,2, Haruhiko Koseki1,2 (1. Graduate School of Medicine, Chiba University, 2. Institute of Medical Science (IMS), RIKEN)
[1P-573]The Elucidation of the effects of Extracellular syntaxin4-induced P-cadherin in ES cells.
○Taisei Mihara1, Yohei Hirai1 (1. Kwansei Gakuin univ. School of biological and environmental science, Dept. Biomedical science)
[1P-574]Role of Sox2 distal regulatory element in mammalian neural development
○Satoe Banno1, Tsukasa Sanosaka1, Noriko Mizota1, Jun Kohyama1 (1. Keio University)
[1P-575]Fetal reprogramming of small intestinal epithelial cells by synthetic hydrogel
○Cewen Chen1, Shinya Tanaka1,2, Masamichi Imajo2 (1. Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, 2. Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University)
[1P-576]IL1R2 maintains epidermal stem cell heterogeneity through crosstalk with niche signaling under skin inflammation
○Hung Manh Phung1,2, Ikuto Nishikawa2,1, Nguyen Thi Kim Nguyen1, Ahmed M. Hegazy1,3, Aiko Sada2,1 (1. IRCMS, Kumamoto Univ., 2. MIB, Kyushu Univ., 3. Zoology Dept., Minia Univ.)
[1P-577]WNT carriers SFRP1 and SFRP2 support hematopoietic cells jointly in an in vitro hematopoietic niche
○Kazuki Tsutsui1, Huki Kumagai1, Hikaru Tsutsumi1, Asuka Tanaka1, Chisaki Nakamura1, Miyu Yoshimura1, Ayu Muranaka1, Hanayo Watanabe1, Kyoka Imoto1, Momoka Sawada1, Yuto Sakurai1, Robert G. Roeder2, Natsumi Hasegawa1, Mitsuhiro Ito1,2 (1. Medical Biophysics, Kobe Univ., 2. Biochem. & Mol. Biol., the Rockefeller Univ.)
[1P-578]Single-cell analysis of the reprogramming process using the cell fusion system
○Taisei Kumazaki1, Chinatsu Yonekawa1, Tomomi Tsubouchi1 (1. NIBB)
[1P-579]Molecular Mechanism Analysis of ES Cell Self-Renewal Using STAT3ER Mutants
○Fujita Jin1, Matsuo Takeshi1, Aoki Yuta1, Ueda Atsushi2, Akagi Tadayuki1 (1. Fukuoka Institute of technology Univ., 2. Tokai Univ.)
[1P-580]Mga directly regulates multiple epigenetic modifications to establish meiotic gene repression.
○Kousuke Uranishi1, Ayumu Suzuki1, Masataka Hirasaki1, Masazumi Nishimoto1, Akihiko Okuda1 (1. Saitama Medical University)
[1P-581]Elevation of point mutations in retrotransposons (SINEs) in iPS cells
○Tomo Suga1, Misato Sunayama1, Yuko Hoki1, Masumi Abe2, Ryoko Araki1 (1. IRS, QST, 2. IQMS, QST)
[1P-582]The Trial of Stemness Maintenance via Syntaxin4-Fragment1 Supplementation in Embryonic Stem Cells
○Yume Inoue1, Yohei Hirai1 (1. Kwanseigakuin Univercity)
[1P-583]Investigation of self-multilayered cells in umbilical cord-derived mesenchymal stem cells
○Mai Mochizuki1,2, Taka Nakahara2 (1. Life Sci. Dent. Univ., 2. Dev. Reg. Dent. Univ.)
[1P-584]Observation of cAMP concentration changes during proliferation, differentiation and quiescence of neural stem cells
○Riko Fujiwara1, Mayumi Yamada2, Tatsushi Yokoyama3, Masayuki Sakamoto1, Itaru Imayoshi1,4 (1. Laboratory of Brain Development and Regeneration, Graduate School of Biostudies, Kyoto University, 2. Laboratory of Cell Biology, Institute for Life and Medical Sciences, Kyoto University, 3. Laboratory of Optical Biomedical Science, Institute for Life and Medical Sciences, Kyoto University, 4. Laboratory of Deconstruction of Stem Cells, Institute for Life and Medical Sciences, Kyoto University)
[1P-585]Diabetic conditions impair the ability of Mesenchymal Stem Cells to Suppress Inflammatory Cytokine on Lung Epithelial Cells Induced by SARS-CoV-2 and Influenza Viral Protein
○Neni Anggraeni1, Khanh Cat Vuong1, Osamu Ohneda1 (1. University of Tsukuba)
[1P-586]Construction and evaluation of Sendai virus vectors using a high-efficient packaging system
○Koichi Saeki1, Hiroki Matsuda1, Hayato Ani1, Ying Yang1, Mariko Shirakawa1 (1. Repli-tech Co., Ltd.)
[1P-587]Comparative analysis of gene transduction efficiency and expression levels between Sendai virus vector and other gene transduction methods
○Hiroki Matsuda1, Ying Yang1, Hayato Ani1, Koichi Saeki1 (1. Repli-tech Co., Ltd.)
[1P-588]Identification of ependymal cells with the function of progenitor cells for the adult brain in larvae of Ciona intestinalis
○Chinatsu Morimoto1, Kotaro Shimai1, Kouhei Oonuma 2, Takehiro G. Kusakabe1 (1. Dept. of Biol., Grad. Sch. of Nat. Sci., Konan Univ., 2. Front. Res. Inst., Chubu Univ.)
[1P-589]A small molecule K-3 promotes PDX1 expression and potentiates the differentiation of pluripotent stem cells into insulin-producing pancreatic β cells
○Yukihiro Shimaya1, Tatsuya Yano2, Nobuaki Shiraki1, Shoen Kume1 (1. Science Tokyo, 2. Daiichi Sankyo Co., Ltd.)
[1P-590]Tunning The Cell Cycle Length by Physical Environment in Early Cortical Development
○Yuzuka Takeuchi1, Mineko Kengaku2, Takumi Kawaue2 (1. Graduate School of Biostudies, Kyoto Univ., 2. iCeMS, KUIAS, Kyoto Univ.)
[1P-591(1AS-14-07)]Inter-lineage Cellular Crosstalk Controlling the Development and Maturation of Hematopoietic Stem Cells
○Mio Nakanishi1 (1. Chiba University)
[1P-592]Regulation of cell fate of adrenocortex-white adipose by inositol phospholipids
○Shogo Yanai1, Junko Sasaki1, Takehiko Sasaki1 (1. Dept. of Biochem. Pathophysiol., MRI, TMDU)
[1P-593]Functional analysis of Axin2 in anterior-posterior patterning in neural development
○Naho Ishiguro1, Noriaki Sasai1, Takuma Shinozuka1 (1. Nara Institute of Science and Technology)
[1P-594]A stress-responsive transcriptional factor drives fate conversion of enteroendocrine cells in Drosophila melanogaster
○Qingyin Qian1, Makoto Hayashi1, Hiroki Nagai2, Ken-ichi Kimura1, Satoru Kobayashi1, Yuichiro Nakajima2, Ryusuke Niwa1 (1. University of Tsukuba, 2. The University of Tokyo)
[1P-595]The Culture Methods for Maintaining the Undifferentiated State of Epidermal Progenitor Cells
○Non Ogashira1, Yohei Hirai1 (1. Kwansei Gakuin University)
[1P-596]The Effect of Substrate Stiffness on the Neural Differentiation of iPS Cells
○JUNYI CHEN1, Tatsuo Michiue1 (1. The University of Tokyo)
[1P-597]Functional analysis of BRINP3 during muscle differentiation
○Yukimi Kitashima1, Yuki Nakayama2 (1. Kumamoto Univ. Grad. Sch. of Sci. and Tech., 2. Kumamoto Univ. Fac. of Adv. Sci. Tech.)
[1P-598]MTCL2 facilitates the multipolar elongation of dendrites in cerebellar granule cells by regulating the interaction between the Golgi apparatus and the microtubule cage surrounding the nuclei
○MARI Minekawa1, Atsushi Suzuki1 (1. Yokohama City University)
[1P-599]Development of novel method for inducing cardiac progenitor cells derived from induced pluripotent stem cells for elucidating the pathophysiology of DiGeorge syndrome
○Yuzuno Shimoda1,3, Nobuyuki Murakoshi2, Dong-Zhu Xu1,2, Yohei Hayashi1,4, Yoshihiro Miwa1,3 (1. University of Tsukuba, Program in Life Science Innovation, 2. Department of Cardiology, Faculty of Medicine, University of Tsukuba, 3. Gene Engineering Division, RIKEN BioResource Research Center, 4. iPS Cell Advanced Characterization and Development Team, RIKEN BioResource Research Center)
[1P-600]Effects of aberrant de novo biosynthesis of ceramides on Dictyostelium development
○Shioin Kimura1, Takaaki Narita2 (1. Graduate School of Advanced Engineering, Chiba Institute of Technology, 2. Department of Life Science, Faculty of Advanced Engineering, Chiba Institute of Technology)
[1P-601]In vitro induction of region-specific glial differentiation from mouse embryonic stem cells
○Takuma Shinozuka1, Noriaki Sasai1 (1. Dev. Biomed. Sci., Div. Bio. Sci., NAIST)
[1P-602]Synthetic biology approach to analyze robustness dependent on feedback in gene circuits for differentiation
○Kohei Uetsuka1, Sota Okuda1, Masaki Takeda1, Mana Hashimoto1, Daisuke Kiga1 (1. Department of Advanced Science and Engineering, Waseda University)
[1P-603]The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells
○Hiromi Shimojo1, Taimu Masaki2,3, Ryoichiro Kageyama2,3 (1. Osaka University, 2. RIKEN, 3. Kyoto University)
[1P-604]Development of a novel treatment for osteosarcoma based on induction of chondrocyte differentiation
○Seim Koo1,2, Makoto Takeuchi1,3, Ryohei Katayama1,2, Satoshi Takagi1 (1. Department of Experimental Chemotherapy, JFCR, 2. CBMS of GSFS, Tokyo University, 3. Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School)
[1P-605]The effect of DKK3/REIC-like proteins on dendritic cell differentiation in the monocytic leukemia cell line THP-1
○Hirofumi Fujita1, Keita Sato1, Rie Kinoshita2, Masakiyo Sakaguchi2, Hideyo Ohuchi1 (1. Dept. of Cyto. & Histo., Okayama Univ., 2. Dept. of Cell Biol., Okayama Univ.)
[1P-606]The Effect of Oxytocin on Mammary Gland Development
○Ami Tosaka1, Wataru Arai1, Rio Maekawa2, Yoshichika Umeno2, Yukako Tokutake2, Shinichi Yonekura1,2 (1. Shinshu University, 2. Shinshu University agricultural department)
[1P-607]Impact of epigenetic modifications downstream of TGF-β signaling underlying nested expression pattern of 5' Hox genes
○Ayana Tatumi1, Miku Takabayashi2, Syun Tomooka3, Takayuki Suzuki1 (1. Grad.School of Sci., OMU, 2. Sch.of Sci., Nagoya Univ., 3. Grad. Sch. of Bioagr.Sci., Nagoya Univ.)
[1P-608]Left-right asymmetry in the basal bodies of the mouse node cilia: implication of a novel mechanism of symmetry breaking which is cilia motility-dependent and fluid flow-independent.
○Hiroshi Yoke1, Atsushi Taniguchi1,2, Shigenori Nonaka1,3 (1. National Institute for Basic Biology (NIBB), National Institutes of Natural Sciences, 2. Research Center of Mathematics for Social Creativity, Research Institute for Electronic Science, Hokkaido University, 3. The Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences)
[1P-609]The transcriptional regulation of the Tbx6 gene to elucidate the mesoderm development from the neuro-mesodermal progenitors.
○Soh Hazaki1, Hitomi Suzuki 1, Yuta Chigi 1, Kaori Tanaka2, Akihito Harada2, Yasuyuki Ohkawa2, Tatsuya Takemoto1 (1. Laboratory of Embryology, Institute of Advanced Medical Sciences, Tokushima University, 2. Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University)
[1P-610(1PS-04-08)]Actin polymerization-driven cytoplasmic streaming in the gonadal syncytium during oogenesis.
○Kenji Kimura1, Fumio Motegi1 (1. Inst. for Genet. Med., Hokkaido Univ.)
[1P-611]Functional analysis of a zinc finger protein that promotes the formation of neural tissue in Xenopus embryos
○Ryota Koike1, Regina P. Virgirinia1, Makoto Nakamura1, Kimiko Takebayashi-Suzuki1, Atsushi Suzuki1 (1. Amphibian Research Center, Grad. Sch. of Integ. Sci. Life., Hiroshima Univ.)
[1P-612]The functions of PEG10 gene conferred by a viral translational mechanism in mammalian development and evolution
○Hirosuke Shiura1, Mayuko Fujii1, Shiryu Ando1, Nozomu Nakashima1, Teruhiko Wakayama2, Takashi Kohda1, Tomoko Kaneko-Ishino3, Fumitoshi Ishino4 (1. Fac. of Life and Env. Sci., Univ. of Yamanashi, 2. Adv. Biotech. Ctr., Univ. of Yamanashi, 3. Sch. of Med., Tokai Univ., 4. Res. Inst., Tokyo Med. Dent. Univ.)
[1P-613]Effects of the in vitro environment on blastomere and nuclear morphology in mouse 2-cell stage embryos.
○Miyabi Morisako1, Tadashi Yamazaki1, Satoshi Kishigami1,2,3 (1. University of Yamanashi Faculty of life and environmental sciences, graduate school, 2. University of Yamanashi Center for advanced Assisted Reproductive Technologies, 3. University of Yamanashi Advanced Biotechnology Center)
[1P-614]Morphological observation of Pleurodeles waltl gastrulation movements
○Suguru Furushima1, Akimasa Fukui1 (1. Chuo university)
[1P-615]Embryonic lethality in VPS35L-deficient mice due to the impaired gastrulation
○Tsubasa Fujita1 (1. Nagoya-city university)
[1P-616]The Role of SMARCA4 in Preimplantation Development
○Fiona Sophia Maria Quirion1, Toshiya Nakahara1, Haruhiko Siomi1 (1. Dept. of Mol. Biol. of Med. Keio University)
[1P-617]Position of the centrosomes regulates pronuclear apposition and parental genome unification in zygotes.
○Yuki Takada1, Shu Hashimoto1, Yoshiharu Morimoto2 (1. Reprod Sci., Grad. Sch. of Med., Osaka Metropol. Univ., 2. Grand Front Osaka Clinic)
[1P-618]The roles and alternative splicing of the bHLH-O genes, dec1 and dec2, during zebrafish development.
○Mika Saito1, Shogo Osaki1, Shogo Ono1, Kyo Yamasu1 (1. Div. Life Sci., Grad. Sch. Sci. Eng., Saitama Univ.)
[1P-619]Transcriptional regulation and functions of zebrafish gbx1 in the developing hindbrain.
○Ayano Tobita1, Ayako Yokokawa1, Seiya Yamaki1, Kyo Yamasu1 (1. Div. Life Sci., Grad. Sch. Sci. Eng., Saitama Univ., Saitama, Japan)
[1P-620]Hes/her gene-mediated patterning of primary neurogenesis in the developing neuroectoderm of zebrafish
○Hiroki Tokizaki1, Momo Turuoka1, Takero Ohyanagi1, Kyo Yamasu1 (1. Div. Life Sci., Grad. Sch. Sci. Eng., Saitama Univ.)
[1P-621]Expression and functional analysis of Prmt1 during early zebrafish development
○Anyu Suginishi1, Keisuke Sato1, Takehiro Yamamoto2, Tomoya Kotani3 (1. Biosystem Sci. Course, Grad. Sch. of Life Sci., Hokkaido Univ., 2. Dept. of Biochem., Sch. of Med., Keio Univ., 3. Dept. of Bio., Grad. Sch. of Sci., Hokkaido Univ.)
[1P-622]Roles of soxB1 in neurogenesis and Notch signaling dynamics in the elongating spinal cord of zebrafish embryos
○Yuto Sato1, Ayu Ishikura1, Tatsuya Yuikawa1, Keiko Nakao2, Kyo Yamasu1 (1. Div. Life Sci., Grad. Sch. Sci. Eng., Saitama Univ., Saitama, Japan, 2. Fac. Medicine, Saitama Medical Univ., Saitama, Japan)
[1P-623]Functional and evolutionary background analysis of transmembrane proteins regulating the honeycomb structure of gonads in C. elegans.
○Kenta Sugiura1, Hidetaka Kosako2, Ken Sato1 (1. IMCR, Gunma University, 2. IAMS, Tokushima University)
[1P-624]Understanding the sex-specific roles of histone modifications during meiosis in teleost fish, medaka (Oryzias latipes)
○Karen Nakamura Ogisawa1, Mariko Kikuchi1, Ryo Maeda2, Kataaki Okubo3, Makoto Tachibana2, Yusuke Takehana4, Minoru Tanaka1 (1. Division of Biological Science, Graduate School of Science, Nagoya University , 2. Laboratory of Epigenome Dynamics, Graduate School of Frontier Biosciences, Osaka University, 3. Department of Aquatic Bioscience, Graduate School of Agricultural and Life Science, The University of Tokyo, 4. Department of Animal Bio-Science, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology)
[1P-625]Regulation of embryo implantation by ergothioneine
○Namika Yoshida1, Ayaka Tanaka1, Kotoha Takaki1, Miyu Yazawa1, Susumu Tanaka1 (1. University of Nagasaki, Siebold)
[1P-626]ELYS is required for pronuclear apposition essential for the subsequent formation of the correct first mitotic spindle in Drosophila
○Kazuyuki Hirai1, Kyoichi Sawamura2 (1. Kyorin Univ., 2. U. of Tsukuba)
[1P-627]Phenotypic analysis of KO mice of Rbmy, a Y-linked multi-copy gene
Miho Terao1, Mika Hirabayashi1, Mio Okamoto1, Karin Sugiyama1, Iku Tsuchiya1,2, Atsumi Tsuji-Hosokawa1,3, ○Shuji Takada1,2 (1. Dept. of Systems BioMed., NCCHD, 2. Dept. NCCHD, Grad. Sch. Med. Dent. Sci., TMDU, 3. Dept. Dev. Biol. Pediatr, Grad. Sch. Med. Dent. Sci., TMDU)
[1P-628]Role of calcium oscillations in chromosome segregation of preimplantation mouse embryos
○Hibiki Sugita1, Shunsuke Takarabe1, Atsuko Kageyama2, Yui Kawata2, Azusa Inoue3, Yoshiteru Kai4, Hironobu Murakami1,2, Naoki Yamashita4, Junya Ito1,2, Naomi Kashiwazaki1,2 (1. Laboratory of Animal Reproduction, Graduate School of Veterinary Sciences, Azabu University, Sagamihara 252-5201, Japan, 2. School of Veterinary Medicine, Azabu University, Sagamihara 252-5201, Japan, 3. Laboratory for Epigenome Inheritance, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan, 4. Reproductive Medicine Research Center, Yamashita Shonan Yume Clinic, Fujisawa 251-0025, Japan)
[1P-629]Effects of granulosa cell removal on ovarian function and fertility in mice
○Tsutomu Endo1,2,3, Mayu Tamemasa1, Kana Hayakawa1,2, Fuka Okada1, Natsumi Oyama1, Kyoko Watanabe1, Tianfu Lai3, Yuki Nakano1, Yoshifumi Fujioka1, Hiroshi Suemizu4, Motohito Goto4, Riichi Takahashi4, Ayako Tomita3, Koji Sugiura3, Naoaki Mizuno1,2, Yoshikazu Hirate1,2, Yoshiakira Kanai3, Masami Kanai-Azuma1,2 (1. Tokyo Medical and Dental Univ. , 2. Tokyo Medical and Dental Univ. CEA, 3. The Univ. of Tokyo, 4. Central Inst. for Exp. Animals)
[1P-630]Motile membrane proteins: CD9 dynamics on the egg membrane
○Chiharu Tsunezumi1, Natsuko Kawano1, Kenji Miyado2 (1. Meiji university, 2. National Center for Child Health and Development)
[1P-631]Effect of DDI-5, a compound inducing sperm formation and activation in C. elegans, on mouse reproduction
○Suzuka Nomura1, Ayane Takemura1, Yoshihiro Shimada1, Arata Honda2, Junya Ito3, Atsuko Kageyama3, Koichiro Kako4, Akiyoshi Fukamizu4, Yukiko Karuo5, Masaaki Omote5, Hitoshi Nisimura1 (1. Dept. Lif. Sci., Fac. Sci. Eng., Setsunan Univ., 2. Ctr. Dev. Adv. Med. Tech., Jichi Med. Univ., 3. Sch. Vet. Med., Azabu Univ., 4. TARA, Tsukuba Univ., 5. Fac. Pharm. Sci., Setsunan Univ.)
[1P-632]Establishment of the mini-oocyte induction system and its application
○Ami Banno1, Kana Mizuno2, Takashi Ishiuchi1 (1. Fac. of Life and Environ. Sci., Univ. of Yamanashi, 2. Fac. of Life and Environ. Sci, Univ. of Yamanashi)
[1P-633]Morphological analysis of gonads and expression analysis of germline markers in juvenile sea cucumbers.
○Koki Fujikawa1, Hideo Dohra2, Masaru Toriyama3, Toru Koike4 (1. Shizuoka Univ., Graduate School of Integrated Science and Technology, 2. Shizuoka Univ., Faculty of Science, 3. Shizuoka Univ., Faculty of Agriculture, 4. Shizuoka Univ., Faculty of Global Interdisciplinary Science and Innovation)
[1P-634]Estradiol-17β regulates smooth muscle tonus via Rho kinase and RNDs in bovine oviductal isthmus during the estrous cycle.
○Sayaka Kubota1, Risa Okawara2, Kohei Kawano1,2, Koji Kimura1,2 (1. Okayama Univ. , 2. Okayama Univ)
[1P-635]Finding the placenta-like tissue in ovoviviparous fish: guppy (Poecilia reticulata)
○Junki Yoshida1,2, Natsuko Kawano1, Eiichi Hondo2, Atsuo Iida2 (1. Meiji University, 2. Nagoya University)
[1P-636]Unraveling the Role of Lamin in Mouse Spermiogenesis
○Mizuho Iizuka1, Kai Otsuka1, Masatoshi Ohga 3, Teruhiko Wakayama2, So Maezawa1 (1. Tokyo Univ. of Sci., 2. Yamanashi Univ., 3. Azabu Univ.)
[1P-637]Effect of BPTES on bovine endometrial senescent cells
○Suzuno Senda1, Rei Ichikawa1, Naoki Yamada1, Sho Nakamura1, Satoshi Ohkura1, Kaede Ito2, Yousuke Sugino3, Kouji Kimura3,2, Shuichi Matsuyama1 (1. Nagoya University Graduate School of Bioagricultural Sciences and School of Agricultural Sciences , 2. Faculty of agriculture, Okayama University, 3. Graduate School of Enviromental and life science , Okayama university)
[1P-638]Analysis of the Molecular Function of Squash, a Crucial piRNA Component for Germline Genome Integrity
○XIN XU1, Ritsuko Suyama1, Taichiro Iki1, Shinichi Kawaguchi1, Toshie Kai1 (1. Germline Biology Group, Graduate School of Frontier Biosciences, Osaka University)
[1P-639]Localization of vascular endothelial growth factor receptor (Flt1 and Flk1) during pregnancy in mice
○mana ohtomo1, Shunsuke Takarabe1, Yui Kawata1, Atsuko Kageyama1, Masatsugu Ema2, Jumpei Terakawa1, Junya Ito1, Naomi Kashiwazaki1 (1. azabu university, 2. shiga university of medical science)
[1P-641]Underlying mechanism of sexual dimorphism in fertility analyzed by using mice with balanced reciprocal translocation
○Makiko Tsutsumi1, Atefeh Joudaki1, Hiroki Kurahashi1 (1. Div. of Mol. Genet., CMS, Fujita Health University)
[1P-642]Screening of candidate genes of ovary-determining gene focused on the W chromosome in emu, Palaeognathae
○Yuki Kimura1, Luisa Matiz-Ceron2, Miki Okuno3, Takehiko Itoh4, Shusei Mizushima1,2, Asato Kuroiwa1,2 (1. Grad. Sch. of Life Sci., Hokkaido Univ., 2. Fac. of Sci., Hokkaido Univ., Hokkaido Univ., 3. Sch. of Med., Kurume Univ., 4. Sch. of Life Sci. and Tech., Tokyo Inst. of Tech.)
[1P-643]HORMAD1 haplo-insufficiency causes oocyte decrease through HORMAD2-dependent apoptosis in mice.
○Hiroshi Kogo1, Manami Fujiwara1, Kotaro Sawada1, Akiko Iizuka-Kogo1, Hanako Yamamoto1, Maiko Ikezawa1, Toshiyuki Matsuzaki1 (1. Gunma University)
[1P-644]Identification of proteins involved in signal transduction with a focus on the egg membrane microdomain at fertilization in Xenopus laevis
○Takashi W. Ijiri1, Hiroki Nakanishi1, Kazutoshi Ozawa1, Tetsushi Iwasaki2, Ken-ichi Sato3 (1. Setsunan Univ., 2. Kobe Univ., 3. Kyoto Sangyo Univ.)
[1P-645]Comparison of the recapitulative pattern during embryo genesis by chromatin accessibility analyses in vertebrates and echinoderms
○Tomomi Fukushima1, Minokawa Takuya1, Tamura Koji1, Masahiro Uesaka1 (1. Tohoku University)
[1P-646]Generation of fully genomically humanized mice by ESC-based two-step genome editing
○Jumpei Taguchi1, Manabu Ozawa1 (1. The Institute of Medical Science, The University of Tokyo)
[1P-647]Non-viral generation of transgenic cynomolgus monkeys via the piggyBac transposon system
○Masataka Nakaya1, Tomoyuki Tsukiyama1 (1. Shiga Univ. Med. Sci. RCALS)
[1P-648(1AS-04-07)]Identification of venom proteins from the parasitoid wasp Asobara japonica, inducing Drosophila imaginal disc degradation that contributes to parasitism success
Takumi Kamiyama1, Yuko Shimada-Niwa1, Hitoha Mori2, Naoki Tani3, Hitomi Takemata-Kawabata2, Mitsuki Fujii2, Akira Takasu4, Minami Katayama2, Takayoshi Kuwabara2, Kazuki Seike2, Noriko Matsuda-Imai5, Toshiya Senda4, Susumu Katsuma5, Akira Nakamura3, ○Ryusuke Niwa1 (1. TARA, Univ. Tsukuba, 2. Biology, Univ. Tsukuba, 3. Kumamoto Univ., 4. KEK, 5. Univ. Tokyo)
[1P-649]Application of a novel high oxygen permeability plate for drug screening using zebrafish
○Shota Kondo1, Yukiya Komada2, Norihiro Nishimura1, Zang Liqing1 (1. MIE UNIVERSITY, 2. Mitsui Chemicals)
[1P-650]Enhancing Zebrafish Model Utility with a 3D zTrap Database and Whole-Body Cell Type Atlas
○Tomoya Shiraki1, Koichi Kawakami1 (1. National Institute of Genetics)
[1P-651]Generation of a transgenic chicken line with reporters for limb bud mesenchyme and apical ectodermal ridge cells
○Yuji Atsuta1, Yi-Chen Chen2, Yuna Hattori1, Tatsuya Takemoto2,3, Daisuke Saito1 (1. Kyushu Univ., 2. Setsuro Tech Inc., 3. Tokushima Univ.)
[1P-652]Nano-structured Environments Enhance Insulin-producing Cell Differentiation and Pancreatic Islet-like Organoid Formation
○Wooyoung Shim1, Ji-Yoon Lee1, Han-Sin Lee1 (1. CellStormer Co., Ltd.)
[1P-653]Three-dimensional structure and function of the cell wall invagination (trabecula) in Caulerpa
○Keisuke Matsuda1 (1. Osaka University)
[1P-654]Refining the genotyping method for live zebrafish embryos
○Yosuke Aihara1, Yusuke Kamachi1 (1. Kochi University of Technology)
[1P-655]Metagenomics Analysis of Wastewater Viral Communities for Evaluating the Sensitivity of Bacteriophage Genome Detection
○Keidai Miyakawa1, Yuki Kawasaki1, Takeru Nakabayashi1, Yuki Maruyama1, Moe Yamazaki1, Satoshi Yuhara1, Yuma Oka1 (1. H.U. Group Research Institute G.K.)
[1P-656]E. coli Genotype-Based In Silico Host Prediction for newly solated Felixounavirus Phage Strains
○Yuki Maruyama1, Takeru Nakabayashi1, Yuki Kawasaki1, Keidai Miyakawa1, Moe Yamazaki1, Takeyuki Kotaka1, Yuma Oka1 (1. H.U. Group Research Institute G.K.)
[1P-657]Investigation of the diversity of intestinal microflora and its relationship with field soil bacteria in Ogimi Village long-lived people
○Ryo Higa1, Hidehiro Yokoda1, Yukitoshi Iha1, Yuko Murayama1, Shinya Ikematsu1 (1. National Institute of Technoligy, Okinawa College)
[1P-658(1AS-01-07)]Gut microbiota as a risk factor for colorectal cancer in patients with familial adenomatous polyposis (FAP)
○Sayaka Mizutani1,4, Felix Salim1, Satoshi Shiba2, Takuji Yamada1, Shinichi Yachida3 (1. Tokyo Institute of Technology, 2. National Cancer Center Research Institute, 3. Osaka Univ., 4. JSPS Research Fellow)
[1P-659]Molecular interaction analysis of “ALGISH”, the artificial symbiotic system between algae and fish
○Yoji Okabe1, Shoji Oda1, Kintake Sonoike2, Takako Masuda3, Naoto Takahata4, Kiminori Toyooka5, Mayuko Sato5, Yayoi Tsujimoto Inui1, Tomoko M. Matsunaga1, Shinichiro Maruyama1, Sachihiro Matsunaga1 (1. Grad. Sch. Front. Sci., Univ. Tokyo, 2. Fac. Edu., Waseda Univ., 3. FRA, 4. AORI, Univ. Tokyo, 5. RIKEN, CSRS)
[1P-660]Effect of Akkermansia muciniphila feeding on lifespan and fat accumulation in Caenorhabditis elegans
○Yuina Nomoto1, Takayuki Wada1, Yoshihiko Tanimoto1,2, Eriko Nakadai(Kage)1,2 (1. Osaka Metropolitan Univ., 2. Kyoto Univ.)
[1P-661]Genetic dissection of Wolbachia-induced virus resistance in Drosophila
○Ryudai Ono1, Syunnosuke Makigi1, Tomomichi Tamura1, Tetsu Uemura1, Syoichiro Kurata1, Naoyuki Fuse1 (1. Tohoku university)
[1P-662]Melanopsin DNA aptamers can regulate input signals of mammalian circadian rhythms by altering the phase of the molecular clock.
○Rika Numano1,2, Kazuo Nakazawa2, Yoshihiro Nakajima3, Yo Kikuchi2 (1. Toyohashi Univ. of Tech., Inst. for Research on Next-Generation Semiconductor and Sensing Sci., 2. Toyohashi Univ. of Tech., 1 Dept. of Applied Chem. and Life Sci., 3. National Inst. of Advanced Industrial Sci. and Tech., Health and Medical Research)
[1P-663]Rhythmic function analysis of photoreceptor melanopsin using a multicolor light source stimulator
○Mayuko Aoto1, Ryutaro Kinoshita1, Sei-ichi Tsujimura2, Rika Numano1,3 (1. Toyohashi Univ. of Tech., Dept. of Applied Chem. and Life Sci., 2. Faculty of Design and Architecture, Nagoya City Univ., 3. Institute for Research on Next-generation Semiconductor and Sensing Sci. (IRES²))
[1P-664(1PS-07-08)]A new approach using continuous and prolonged measurements reveals new mechanisms in the Drosophila body temperature rhythm.
○Tadahiro Goda1, Fumika Hamada1 (1. UC Davis)
[1P-665]Analysis of dynamics changes of supersulfides production in golden hamsters during hibernation
○Chiharu Miura1, Airi Nishida1, Yoshifumi Yamaguchi2,3, Hideshi Ihara1, Shingo Kasamatsu1 (1. Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Metropolitan Univ., 2. Hibernation Metab, Physiol. and Deve.Group, ILTS., Hokkaido Univ., 3. Div. of Biosphere Sci., Grad. Sch. of Env. Sci., Hokkaido Univ.)
[1P-666]Gene expression in the embryonic brain is affected by paternal aging in a sex-specific manner
○Haruka Endo1, Takako Kikkawa1, Noriko Osumi1 (1. Department of Developmental Neuroscience Tohoku University Graduate School of Medicine)
[1P-667]Photoconvertible protein Dendra2 reveals the influence of LC3-affinity-defective mutation on SQSTM1 dynamics
○Kento Shimakura1, Chisa Yamaguchi2, Haruka Yudahira3, Akira Oka1, Asako Otomo1, Shinji Hadano1 (1. Dept. of Physiol., Tokai Univ. Sch. Med., Kanagawa, Japan, 2. Cent. for Med. Res. & Edu., Tokai Univ. Sch. Med., Kanagawa, Japan, 3. Tokyo Met. Neurol. Hosp., Tokyo, Japan)
[1P-668]A novel mechanism of dendritic refinement in postnatal mouse barrel cortex unveiled by rapid protein knockdown
○Ayane Nihashi1,6, Naoki Nakagawa1,6, Takuya Sato1, Mariko Yamamoto2, Luwei Wang1,6, Rieko Ajima3,6, Yumiko Saga4, Yumiko Yoshimura2,6, Masato Kanemaki5,6, Takuji Iwasato1,6 (1. Mammalian Neural Circuits Lab., NIG, 2. Visual Information Processing Div., NIPS, 3. Embryology Div., NIBB, 4. Mammalian Development Lab., NIG, 5. Molecular Cell Engineering Lab., NIG, 6. Graduate Institute for Advanced Studies, SOKENDAI)
[1P-669]Cortical development under circadian control
○Lingyan Fang1, Takaaki Kuniya1, Sara Kukimoto1, Megumi Hatori2, Tsuyoshi Hirota2, Yukiko Gotoh1,3 (1. The Univ. of Tokyo, 2. Nagoya Univ., 3. WPI-IRCN, The Univ. of Tokyo)
[1P-670]Functional analysis of the novel membrane protein TMEM196 in neural development
○Yumi Matsumoto1, Takuma Shinozuka1, Yuichi Sakumura2, Noriaki Sasai1 (1. Dev. Biomed. Sci., NAIST, 2. DSC, NAIST)
[1P-671]Analysis of local translation around the myelin sheath of axons
○Mayu Hayashi1, Akinobu Matsumoto1 (1. Graduate School of Science, Nagoya Univ.)
[1P-672]Functional role of circular RNAs in postnatal brain development
○Luc Gailhouste1, Mizuki Kurosawa1, Mika Takahashi1, Aya Ito-Ishida1 (1. RIKEN Center for Brain Science)
[1P-673]Functional analysis of BCAS1, a protein involved in myelin formation
○Tetsuya Ishimoto1,2, Hisashi Mori1,2 (1. Dpt. Med., Univ. Toyama, 2. Idling Brain, Univ. Toyama)
[1P-674]Daughterless regulates differentiation the neuroepithelial cells – neural stem cells
○Chika Akiba1, Aya Takezawa2, Takumi Suzuki1 (1. Dept. of Biol., Grad. Sch. of Sci. and Eng., Ibaraki Univ., 2. Dept. of Biol., coll. of Sci., Ibaraki Univ.)
[1P-675]Requirement for auditory inputs in the morphological development of layer 4 neuron in the auditory cortex
○AOI NOHARA1, CARINA HANASHIMA2 (1. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, 2. Faculty of Education and Integrated Arts and Sciences, School of Education, Waseda University)
[1P-676]A novel mechanism for altering microglial properties mediated by purine metabolisms
○Rin-ichiro Teruya1, Fuminori Tsuruta2 (1. Graduate School of Science and Technology, Degree Programs in Life and Earth Sciences, Doctoral Program in Biology, Tsukuba Univ, 2. Institute of Life and Environmental Sciences, Tsukuba Univ)
[1P-677]The effect of cGAS on CAMs state regulation and meningeal structure formation
○Chihiro Hiraki1, Fuminori Tsuruta2 (1. Grad. Sch. of Life and Env. Sci., Univ. of Tsukuba, 2. Fac of Life and Env. Sci., Univ. of Tsukuba)
[1P-678]The mechanism of astrocyte production in the developing chick pallium
○Senri Doi1,2, Takuma Kumamoto2, Kei Yura1,3, Chiaki Ohtaka Maruyama2 (1. Ochanomizu Univ., Sci., Biol., 2. Developmental Neuroscience Project, Tokyo Metropolitan Institute of Medical Science, 3. Waseda Univ., Department of Life Science & Medical Bioscience, School of Advanced Science and Engineering)
[1P-679]TRPV4 activation and gliotransmitter release in astrocyte
○Koji Shibasaki1, Rimika Kabashima1 (1. University of Nagasaki)
[1P-680]Remodeling of the capillary vessels in denervated muscle by nerve injury
○Yurie Sato1, Takeyasu Maeda1 (1. Center of Advanced Oral Science Niigata Univ.)
[1P-681]Effects of cortisol on brain development in zebrafish
○Hiromu Nakano1, Keishi Takeda1, Maiko Higuchi1 (1. Rikkyo university)
[1P-682]Intracellular calcium dynamics of glial ependymal cells in the brain vesicle and the motor ganglion of the ascidian larva
○Maasa Kondo1, Chinatsu Morimoto1, Nanako Okawa1,2, Kouhei Oonuma3, Atsushi Kuhara1, Takehiro G. Kusakabe1 (1. Dept. of Biol., Grad. Sch. of Nat. Sci., Konan Univ., 2. Grad. Sch. of Front. Biosci., Osaka Univ., 3. Front. Res. Inst., Chubu Univ.)
[1P-683]Searches for social experience-responsive genes that modulate same-sex courtship behavior in Drosophila fruitless mutant males
○Toranosuke Nagamatsu1,2, Daniel J Rindner2, Kenta Tomihara2, Yusuke Hara2, Daisuke Yamamoto2, Kosei Sato1,2 (1. University of Hyogo , 2. National Institute of Information and Communications Technology)
[1P-684]Elevated alcohol consumption and tolerance due to nucleocytoplasmic transport dysfunction
○Yoshiatsu Aomine1, Koki Sakurai1, Jun Adachi2, Tom Macpherson1, Takaaki Ozawa1, Yoichi Miyamoto3, Yoshihiro Yoneda4, Masahiro Oka3, Takatoshi Hikida1 (1. Lab. for Advanced Brain Functions, IPR, Osaka Univ., 2. Lab. of Proteomics for Drug Discovery, NIBIOHN, 3. Lab. of Nuclear Transport Dynamics, NIBIOHN, 4. Res. Found. for Microbial Diseases of Osaka Univ.)
[1P-685]Cholinergic neuromodulation of interhemispheric inhibition in the mouse motor cortex
○Takashi Handa1, Qing Zhang1, Hidenori Aizawa1 (1. Hiroshima Univ.)
[1P-686]Role of the thalamostriatal pathway in marmosets
○Shigeki Kato1, Masaaki Sugawara1, Miwako Yamasaki2, Masahiko Watanabe2, Ken-ichi Inoue3, Katsuki Nakamura4, Masahiko Takada3, Kazuto Kobayashi1 (1. Dept. Mol. Genet., Fukushima Med. Univ., 2. Dept. Anat., Hokkaido Univ., 3. Syst. Neurosci., Evo. Orig. Hum. Behav., Kyoto Univ., 4. Cogn. Neurosci., Evo. Orig. Hum. Behav., Kyoto Univ.)
[1P-687]Fatty acid metabolism outside the mitochondria via HADH regulates temperature acclimation
○Yukina Mori1, Akihisa Fukumoto1, Misaki Okahata1, Toru Miura1, Yohei Minakuchi2, Atsushi Toyoda2, Akane Ohta1, Atsushi Kuhara1,3 (1. Laboratory of Molecular and Cellular Regulation Graduate school of Natural Science Konan University, 2. National Institute of Genetics, Japan, 3. PRIME, AMED)
[1P-688]Social environment affects symptoms of MRD43, mental retardation autosomal dominant 43
○Tsuyoshi Takagi1, Masato Asai1 (1. Aichi Developmental Disability Center)
[1P-689]Analysis of abnormal oxytocin secretion observed in β-secretase-deficient mice and its effects on development and neglect behaviour
○Yoshihiro NISHIDA1, Yuta TUBOUCHI2, Hiroyuki YANO3, Rhoji HAMANAKA2 (1. Dept.of Obstet and Gynecol., Faculty of Medicine, Oita University, 2. Dept. of Health Sci., Div.of Human Biol., Oita Univ. of Nursing and Health Sci., 3. Dept. of Radiol. Sci., Junshin Gakuen Univ.)
[1P-690]Searching for neurons preferentially active during forward or backward locomotion in Drosophila larvae with a photoconvertible calcium sensor.
○Masayoshi Sato1, Takahisa Date2, Akinao Nose1,2 (1. Dept. Complex Sci. & Engn., Grad. Sch. Frontier Sci., Univ. of Tokyo, 2. Dept. Phys., Grad. Sch. Sci., Univ. of Tokyo)
[1P-691]Elucidating the genetic basis of left-right dimorphism in Drosophila's brain and its implication on mating fitness
○Wai Cheng Wong1, So Sakamura2, Tomoki Yoshida1, Eita Yoshitake1, Suyama Komomo1, Kenji Matsuno1 (1. Osaka University, 2. University of Hyogo)
[1P-692]Investigation of the mechanism of defecation control by the central nervous system with a focus on neuropeptides
○Takuto Matano1, Hiromi H Ueda1, Jannatul Ferdous1,2, Mitsuya Shiraishi1, Kiyotada Naitou1 (1. Kagoshima University, 2. Bangladesh Agricultural University)
[1P-693]Astrocytic IP3/Ca2+ Signaling Regulates Extracellular Potassium Ions during Depression-Like Behaviors
○Chihiro Kobayashi1, Ai Inome2, Hiromu Monai1,2 (1. Graduate School of Humanities and Sciences, Ochanomizu University, Tokyo, Japan, 2. Department of Biology, Faculty of Science, Ochanomizu University, Tokyo, Japan)
[1P-694]Drosophila model of stress-induced sleep disorder using locomotor restriction
○Akari Yasuda1, Takaomi Sakai1 (1. Tokyo Metropolitan University)
[1P-695(1PS-07-04)]Challenges in revealing neural basis of formulating and testing a hypothesis via longitudinal imaging of neural activity
○Chika Nishimura1, Yuki Hashizume1, Haruto Ueno1, Kohei Morimoto3, Makoto Fukushima2, Seiya Mizuno4, Hiroki Yagi1, Satoshi Yawata1, Ken Kobayashi1, Dai Watanabe1 (1. Grad Sch Med, Kyoto University, Japan, 2. Grad Sch Adv Sci, Hiroshima Univ, Hiroshima, Japan, 3. Grad Sch Inf, Kyoto Univ, Kyoto, Japan, 4. Institute of Medicine, University of Tsukuba)
[1P-696]Evaluation of piperine preference mechanisms and physiological effects using C. elegans as a model animal.
○Kyoko Chiba1, Seiryu Ishikawa2, Akane Ohta3, Atsushi Kuhara3, Yoshihiko Tanimoto4,1, Eriko Nakadai(Kage)4,1 (1. Osaka Metropolitan Univ., 2. Osaka City Univ., 3. Konan Univ., 4. Kyoto Univ.)
[1P-697]Individual testing of herbal medicines that reduce mouse biting behavior, within mixed components of Japanese traditional herbal medicine, Kamishoyosan
○Kento Igarashi1, Satoshi Kuchiiwa2, Toshiko Kuchiiwa3,2, Tomoaki Sato1 (1. Kagoshima Univ. Dept. Applied Pharmacol., 2. Kagoshima Univ. Dept. Neuroanatomy, Field of Neurol., 3. Kagoshima Immaculate Heart Univ. Dept. of Clinical Pshychol.)
[1P-698]Effect of gut metabolites on the development of social brain via nuclear receptor, CAR
○Akihito Yasuoka1, Ryuya Narita1, Takashi Kondo2, Keiko Abe3 (1. Seitoku University, 2. RIKEN Cent. for Int. Med. Sci., 3. Grad. Sch. of Agric. and Life Sci., The Univ. of Tokyo)
[1P-699]Evaluation of GDNF: a candidate gene of stress tolerance index in chickens
○Takumi Fuse1, Sana Atsumi2, Suzuka Kohno3, Shinichi Yonekura1,2, Yukako Tokutake1,2 (1. Shinshu Univ., 2. Shinshu Univ. agricultural department, 3. Tohoku Univ.)
[1P-700]Analysis of inter-batch variation in IMPC behavioral phenotyping
○Ikuko Yamada1, Tomoko Kushida1, Tamio Furuse1, Masaru Tamura1 (1. RIKEN BioResource Research Center)
[1P-701]Pharmacological Study of Diacylglycerol Kinase Beta (DGKβ) in a Mouse Model of Depression
○Joichiro Muramatsu1, Hinata Sasaki2, Koji Yamashita2,3, Takeshi Kawano2,3, Rika Numano1,3 (1. Toyohashi university of Technology Department of Applied chemistry and Life science, 2. Toyohashi university of Technology Department of Electrical and Electronic Information Engineering, 3. Toyohashi university of Technology Institute for Research on next-generation Semiconductor and Sensing Science)
[1P-702]Measurement of brain activity in estrogen-deficient mice using Toyohashi probe
○Kaname Takada1, Yamashita Koji2, Tadahiro Iimura4, Rika Numano1,3 (1. Dept. of Applied Chem. And Life Sci, Toyohashi Univ. of Tech, 2. Dept.of Electrical and Electronic Information Engineering, Toyohashi Univ. of Tech, 3. Institute for Research on next-generation Semiconductor and Sensing Science, Toyohashi Univ. of Tech., 4. Department of Pharmacology, Graduate School of Dental Medicine, Hokkaido Univ.)
[1P-703(1AS-07-03)]Anti-Aβ antibody resolves the post-stroke neural reparative function impaired by Aβ pathology
○Kento Otani1,2, Koji Hase2, Takashi Saito3, Takashi Shichita1 (1. Department of Neuroinflammation and Repair, Medical Research Institute, Tokyo Medical and Dental University, 2. Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Keio University., 3. Department of Neurocognitive Science, Institute of Brain Science, Graduate School of Medical Sciences, Nagoya City University)
[1P-704]Transcriptomic Landscape of Glia cells in Mouse Models of Social Dysfunction and Oxytocin-Mediated Recovery
○Masafumi Tsurutani1,2, Kazunari Miyamichi1 (1. RIKEN BDR, 2. Kyoto Univ.)
[1P-705]A novel aquaporin-4-associated optic neuritis animal model with serve neuronal dysfunction
○Yuko Morita1, Takahide Itokazu1,2, Toshihide Yamashita1,2,3 (1. Dept. of Molecular Neuroscience, Grad. Sch. of Med., Osaka Univ., 2. Dept. of Neuro-Medical Science, Grad. Sch. of Med., Osaka Univ., 3. Immunology Frontier Research Center, Osaka Univ.)
[1P-706]RNA-mediated autoregulatory dysfunction in ALS-linked TARDBP mutations
○Shingo Koide1, Akihiro Sugai1, Genri Toyama1, Ekaterina Nadbitova2, Yumi Yamada1, Takuma Yamagishi1, Osamu Onodera1,2 (1. Department of Neurology, Brain Research Institute, Niigata University, 2. Department of Molecular Neuroscience, Brain Science Branch,Brain Research Institute, Niigata University)
[1P-707]Human Amyloid β Cytotoxicity Causes Embryonic Lethality via the Protein Processing in Endoplasmic Reticulum Pathway in Embryogenesis of C. elegans
○Mao Onishi1, King Law1, Mitsuki Ohara1, Yukihiko Kubota2, Masahiro Ito1,2 (1. Dept. of Life Sci., Grad.Sch. of Life Sci., Ritsumeikan Univ. , 2. Dept. of Bioinfo., Col. of Life Sci., Ritsumeikan Univ.)
[1P-708]Pathophysiological analysis of pyruvate dehydrogenase deficiency using disease-iPS cells
○Tomoyuki Abe1, Eiji Sakashita2, Kenji Kuroiwa2, Katsumi Kasashima2, Yutaka Inoki2, Eriko Ohta2, Chiyoko Kato2, Shigeaki Miyabayashi3, Kaoru Tominaga2, Hitoshi Endo2 (1. Center for Development of Advanced Medical Technology, Jichi Medical University, 2. Department of Biochemistry, Jichi Medical University, 3. Miyabayashi KODOMO Clinic)
[1P-709]KeyMolnet enables molecular network analysis of multi-omics data.
○Rie Taniguchi1, Miki Shigetaka1, Yoko Inoue1, Nakako Iwasaki1, Mieko Ohota1, Kazuko Mashino1, Shizuka Miyahara1, Makoto Shigetaka1 (1. KM Data.Inc.)
[1P-710]Loss of function of GBA1b exacerbates abnormal lipid metabolism in PLA2G6 knockout Drosophila.
○Mai Shimizu1, Kahori Shiba-Fukushima2, Ryota Kasahara3, Noriko Ueno4, Yoshiki Miura5, Nobutaka Hattori1,2,6,7, Yuzuru Imai1,7 (1. Juntendo Univ. Med. Neurology , 2. Juntendo Univ. Med. Drug Development for PD, 3. Juntendo Univ. Med. Genomic and regenerative medicine, 4. Juntendo Univ.Pharm.Drug Discovery Science. , 5. Juntendo Univ. Med. Biomolecular Science, 6. RIKEN CBS. Neurodegenerative disorder collaboration., 7. Juntendo Univ.Research for PD)
[1P-711]CHCHD2 P14L, found in amyotrophic lateral sclerosis, alters Ca2+ homeostasis, leading to TDP-43 processing and aggregation
○Yuzuru Imai1, Aya Ikeda2, Hongrui Meng1, Manabu Funayama2, Nobutaka Hattori2,1,3 (1. Juntendo Univ. Grad. Sch. Med. Parkinson, 2. Juntendo Univ. Med. Neurol., 3. RIKEN CBS)
[1P-712]Comparison and identifiability of functional brain networks in patients with mild cognitive impairment and healthy controls
○Chisho Takeoka Takeoka1, Tetsushi Yada1, Toshimasa Yamazaki2, Yoshiyuki Kuroiwa3, Kimihiro Fujino3, Toshiaki Hirai3, Hidehiro Mizusawa4 (1. Grad. Sch. of Comp. Sci. Syst. Eng., Kyutech., 2. Office for Career Support, Sch. of Comp. Sci. Syst. Eng., Kyutech., 3. Mizonokuchi Hospital, Teikyo Univ. Sch. of Med., Dept. of Neurol., 4. National Cent. of Neurol. and Psych.)
[1P-713]ALS-linked Y374X TDP-43 truncation retains G-quadruplex binding but exhibits reduced liquid-liquid phase separation
○Yusaku Kasuga1, Akira Katayama2, Kaneyoshi Yamamoto1, Akira Ishiguro1 (1. Hosei Univ., 2. Japan Medical Univ.)
[1P-714]Neuroprotective effect of Yinaoxin Granules on ferroptosis following cerebral ischemia reperfusion injury
○Weng Jingyu1, Xu Hongbo1, Li Shuming1, Liu Lang1 (1. Shaanxi University of Chinese Medicine Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, 712083, Xianyang, PR China)
[1P-715]Involvement of the neutral lipid metabolism inα-Synuclein aggregation and development of a screening system for lipid-associated Parkinson's disease modifying agents.
○Ryota Kasahara1,2,3, Jun Ogata1,3, Nobutaka Hattori1,2,3, Yuzuru Imai1,3 (1. Juntendo Univ. Dept. Neurol., 2. Juntendo Univ. Cent. Genomic&Regen Med., 3. Juntendo Univ. Dept. Res of PD.)
[1P-716]Helicobacter pylori outer membrane vesicles enhance microglial autophagy pathways and their involvement in Alzheimer's disease
○Ah-Mee Park1,2, Fumitaka Sato2, Cong Thanh Nguyen2, Ijaz Ahmad2, Seiichi Omura2, Reona Shiro3,2, Ikuo Tsunoda2 (1. Kindai Univ. Facul.Med. Dpt. Arts Sci., 2. Kindai Univ. Facul.Med. Dpt. Microbiol. , 3. Kindai Univ. Facul.Med. Dpt. Ob/Gyn)
[1P-717]Analysis of neurodevelopmental toxicity of insecticides and flame retardants using human cultured cell lines
○Tomohiro Ito1, XianYang Qin2, Yoshika Kurokawa1, Hideko Sone1,3 (1. National Institute for Environmental Studies, 2. RIKEN, 3. Yokohama University of Pharmacy)
[1P-718]Changes of retinal Syntaxin 1A in a rat model of Retinitis Pigmentosa
○Hinami Sashi1, Hideki Hayashi1, Mio Kikuchi1, Kenshou Amemiya1, Yui Iwatani1, Yoshiyuki Moriyama1, Norio Takagi1 (1. Dept. Appl. Biochem., Sch. of Pharm., Tokyo Univ. Pharm. Life Sci.)
[1P-719]Examination of the genetic and physical interactions between Ric and dopamine transporter.
○Ririka Itoh1, Tomohiro Chiyonobu2, Hideki Yoshida1 (1. Dept. of Appl. Biol., Kyoto Inst. of Technol.,, 2. Dept, of Pediatrics, Kyoto Pref. Univ. of Med.)
[1P-720]Carnosine Improves Memory Function via Exosomes
○Yuki Karan1, Miyazono Sunao1, Udono Miyako2, Katakura Yoshinori2 (1. Grad. Sch. Biores Bioenv. Sci., Kyushu Univ., 2. Fac Agr., Kyushu Univ.)
[1P-721]Microglial changes in HTRA1-associated cSVD model: analysis of the single-cell transcriptome
○Shin Koide1, Taisuke Kato1, Osamu Onodera1 (1. Brain Research Institute, Niigata University)
[1P-722]Effects of phosphorylation and stabilization of nuclear SP1 by nicotinic receptor activation in BACE1, the rate-limiting enzyme for Aβ production
○Masaki Nakano1, Masaki Nishimura1,2 (1. Molecular Neuroscience Research Center, Shiga University of Medical Science, 2. Department of Neurology, Yoka Municipal Hospital)
[1P-723]Importance of Calreticulin in a mouse Parkinson’s disease model.
○Norika Doi1, Osamu Hori1 (1. Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University)
[1P-725]Perturbation of maternal gut microbiota during pregnancy affects postpartum maternal behavior through modifications in stress response and brain metabolism in mice
○Shiro Tochitani1, Yasuko Yamamoto2, Kuniaki Saitou2, Kentaro Nagaoka3 (1. Graduate School of Health Science, Suzuka University of Medical Science, 2. Fujita Health University Graduate School of Health Sciences, 3. Graduate School of Agriculture, Tokyo University of Agriculture and Technology)
[1P-726]Aberrant decrement of multiple transcription factors regulating expression of the ADAR2 gene ADARB1 underlies the death of the spinal motor neurons of sporadic ALS patients
○Naoki HIROSE1,2, Sayaka TERAMOTO1,3,4, Takenari YAMASHITA1, Hitoshi AIZAWA3,4, Shin KWAK1,3,4 (1. Grad. School of Med., Univ. of Tokyo, 2. Grad. School of Med., Osaka Univ., 3. Dep. Molecular Neuropathogenesis, Tokyo Medical Univ., 4. Dep. Neurology, Tokyo Medical Univ.)
[1P-727]The transcription factor Nrf3 contributes to cancer immune evasion through the autophagic degradation of MHC-I.
○Ayuka Makino1, Miki Nukushina1, Ayaka Wada1, Iori Aketa1, Shuuhei Hirose1, Tsuyoshi Waku2, Akira Kobayashi1,2 (1. Dept. of Life Sys., Grad. Sch. of Life and Med. Sci., Doshisha Univ, 2. Dept. of Life Sys., Fac. of Life and Med. Sci., Doshisha Univ.)
[1P-728]CCL20 knockout mice exhibit mild skin inflammation in psoriasis and atopic dermatitis
○Supanuch Ekronarongchai1, Nozomi Sachi1, Yomei Kagoshima1, Yasuhiro Soga1, Sotaro Ozaka1, Naganori Kamiyama1, Takashi Kobayashi1 (1. Department of Infectious Disease Control, Faculty of Medicine, Oita University)
[1P-729(1PS-13-03)]Transcriptional-metabolic reprogramming controls inflammatory memory in macrophages
○Seonghyeon Hong1, Tomoaki Koga1, Naofumi Funagura1, Mitsuyoshi Nakao1 (1. Kumamoto Univ.)
[1P-730]Uncovering the Iron-Driven Tumor Immune Regulatory Mechanism
○Suzu Yoshitomo1,2, Ayato Maeda1,2, Akihiro Nita1,2, Toshiro Moroishi1,2 (1. 1.Department of Molecular and Medical Pharmacology, Faculty of Life Sciences, Kumamoto University, 2. 2.Center for Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University)
[1P-731]Availability of 5-Aminosalicylic Acid for the Safe and Long-Term Use of Sennoside
○Yusuke Hara1, Rei Kawashima2, Shun Tamaki2, Tatsunori Maekawa2, Ichikawa Takafumi2 (1. Department of Gastroenterology, Kitasato University Graduate School of Medical Sciences, 2. Department of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences)
[1P-732]CD36 is an inhibitory receptor for anti-tumor immune response
by CpG DNA/CXCL14
○Manaka Hasebe1,2, Kosuke Tanegashima1, Risa Saito1,3, Riku Takahashi1,3, Takahiko Hara1,2,3 (1. Tokyo Metropolitan Institute of Medical Science, 2. Grad. Sch. of Tokyo Metropolitan University, 3. Grad. Sch. of Tokyo Medical and Dental University)
[1P-733]Development of therapeutic and diagnostic monoclonal antibodies recognizing a pancreatic cancer-specific surface antigen
○Yuri Matsuoka1, Shun Ohki1, Rin Yoshizato2, Yasuo Kitajima1, Keita Yamane1, Yohei Kawano1, Tomoharu Yasuda1 (1. Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 2. Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University)
[1P-734]Sandwich ELISA for the detection of bovine A1 beta-casein
Tomoe Kobayashi1, Ayumi Watanabe2, Takashi Kuramoto2, ○Makoto Matsuyama1 (1. Shigei Med. Res. Inst., Div. of Mol. Genetics, 2. Tokyo Univ. of Agri., Lab. of Anim. Nutrition,)
[1P-735]Analysis of the effect of Lactobacillaceae on Drosophila innate immunity
○Toshio Shibata1, Keisuke Narumi2, Hiroki Murakami2, Shunjiro Kobayashi2 (1. Dept Biol, Fac Sci, Kyushu Univ., 2. Milk Science Research Institute, Megmilk Snow Brand Co.,Ltd.)
[1P-736]Epstein-Barr virus induced 3 (EBI3), a component of heterodimer cytokine, attributes to TLR7-mediated splenomegaly and bicytopenia
○Masanori Iseki1, Yuma Sakamoto1, Daiki Takezaki1,2, Yoshihiro Matsuda1,2, Mariko Inoue3, Shin Morizane2, Tomoyuki Mukai1 (1. Dept. of Immunol. & Mol. Genet., Kawasaki Med. Sch., 2. Dept. of Dermatol., Grad. Sch. of Med. Dent. & Pharma. Sci., Okayama Univ., 3. Med. Bioresour. Res. Unit, Cent. Res. Inst., Kawasaki Med. Sch.)
[1P-737(1AS-10-05)]Fibroblast heterogeneity in the healthy and injured lung
○Tatsuya Tsukui1, Dean Sheppard1 (1. University of California, San Francisco)
[1P-738]Kinesin molecular motor KIF11 functions during innate immune responses
○Takeshi Kinoshita1, Daisuke Inoue2, Kohsuke Tsuchiya1, Takashi Suda1 (1. Cancer Res. Inst., Kanazawa-university, 2. Faculty of Design, Kyushu University)
[1P-739]c-SMAC formation determines the fate of double positive T cells in thymic selection
○Hitoshi Nishijima1, Wakamatsu Ei1, Machiyama Hiroaki1, Takeuchi Arata1, Furuhata Akie1, Toyota Toyota1, Yokosuka Tadashi1 (1. Tokyo medical university)
[1P-740]Dendritic cells are activated by tumor cells via TLR2 and suppress the proliferation of the tumor cells
○Cheng Han1, Kazuyuki Furuta1, Yohei Chishaki1, Mina Tokyu2, Kazuya Ishikawa1, Chikara Kaito1 (1. Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2. Okayama University, Faculty of Pharmaceutical Sciences)
[1P-741]Delivery of CRISPR-Cas9 by Lipid Nanoparticles (LNP) into Mouse Hematopoietic Stem Cells (HSC) to Cure Immunodeficiency
○Kayoko Shinozaki1,2, Toru Uchiyama3, Toru Yasuda3, Yuichiro Miyaoka1,2,4 (1. Reg. Med. Project, Tokyo Met. Inst. of Med. Sci., 2. Grad. Sch. of Tokyo Med. and Dent. Univ., 3. Div. of Molecular Pathogenesis, National Center for Child Health and Development, 4. Grad. Sch. of Hum. and Sci. Ochanomizu Univ.)
[1P-742]Mucociliary transport in tracheas of mice with ovalbumin-induced allergy
○Shu Takahashi1, Tsubasa Kobayashi1, Mari Tenno1, Yuto Uebayashi2, Nobukiyo Tanaka3, Susumu Nakae4, Koji Ikegami5, Daisuke Kitamura1, Tomoko Masaike3 (1. Grad. Sch. of Biol. Sci., Tokyo Univ. of Sci., 2. Grad. Sch. of Sci. and Tech., Tokyo Univ. of Sci., 3. Dept. Appl. Biol. Sci., Tokyo Univ. of Sci., 4. Grad. Sch. of Integrated Sci. for Life, Hiroshima Univ., 5. Grad. Sch. of Biomed. & Health Sci., Hiroshima Univ.)
[1P-743]Interferon-γ-induced Th1-type regulatory T cells limit exacerbation of experimental autoimmune encephalomyelitis
○Masaaki Okamoto1, Naganori Kamiyama4, Takashi Kobayashi4,5, Masahiro Yamamoto1,2,3 (1. Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, 2. Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, 3. Department of Immunoparasitology, Center for Infectious Disease Education and Research, Osaka University, 4. Department of Infectious Disease Control, Faculty of Medicine, Oita University, 5. Research Center for GLOBAL and LOCAL Infectious Diseases, Oita University)
[1P-744]Regulation of inflammatory disease pathogenesis by long non-coding RNAs
○Kanako Tezuka1, Tomoki Chiba1, Hiroshi Asahara1 (1. Insitute of Science Tokyo)
[1P-745(1AS-02-03)]Nucleolar abnormalities induce the formation of XPG-dependent RNA-DNA hybrids, contributing to the pathogenesis of ribosomopathies through the priming of innate immune response
○Ken Takashima1, Hiroyuki Oshiumi1 (1. Kumamoto university)
[1P-746]Reitakutsukito-ka-shin'i ameliorates olfactory dysfunction by enhancing the replenishment of olfactory sensory neurons in mice with chronic rhinosinusitis.
○Keita Hasegawa1, Kanako Shinguchi1, Shigeki Chiba1 (1. Pharmaceutical Company Kracie, Ltd.)
[1P-747]EVs containing Regucalcin suppress cancer proliferation by
regulating macrophage differentiation.
○Naoomi Tominaga1, Saki Horie1, Kana Tominaga2, Yuta Miyagi1, Masayoshi Yamaguchi3 (1. Yamaguchi Univ., Grad. school of Med., 2. Yamaguchi Univ., Grad. school of Med., Brain, 3. Univ. of Hawaii Cancer Ctr.)
[1P-748]Screening for anti-osteoporotic drug using NanoLuc method for detection of RANK-RANKL binding
○Ken-ichi Nakahama1, HIroyuki Nakamura2, Tomoya Doi3, Masako Akiyama4, Masahiro Shinohara5 (1. Dept. Cellular Physiological Chemistry Grad. Sch. Tokyo Medical and Dental Univ., 2. Laboratory For Chemistry and Life Science, Tokyo Institute of Technology, 3. School of Life Science and Technology, Tokyo Institute of Technology, 4. URA, Tokyo Medical and Dental Univ., 5. Department of Rehabilitation for the Movement Functions, Research Institute, National Rehabilitation Center for Persons with Disabilities)
[1P-749]Essential role of ER membrane complex subunit 1 (EMC1) in B cell homing and humoral immunity
○Kazuhiko Kawata1, Chie Kikutake2, Mikita Suyama2, Yoshihiro Baba1 (1. Division of Immunology and Genome Biology/ Medical Institute of Bioregulation, Kyushu University, 2. Medical Institute of Bioregulation, Bioinformatics, Kyushu University)
[1P-750]Effects of Taurine on Toll-Like Receptor 7 Mediated Inflammation
○Yasuyuki Kobayashi1, Rio Saeki1, Kaho Ishiyama1, Masumi Tadachi1, Akihisa Morito1 (1. TAISHO PHARMACEUTICAL HOLDINGS CO., LTD.)
[1P-751]Inhibition of RFFL function corrects the acquired CFTR dysfunction and suppresses excessive airway inflammatory responses.
○Daichi Hinata1, Shiori Beppu1, Yuka Kamada1, Tsukasa Okiyoneda1 (1. Dept. of Biomed. Sci., Sch. of Biol. and Env. Sci., Kwansei Gakuin Univ.)
[1P-752]Environmental Exosomes ~ Whether does it play some role in the inter-individual communication of aquatic organisms?~
○Ryo Yonezawa1, Lingxin Meng1, Susumu Mitsuyama1, Takanori Kobayashi1, Kazutoshi Yoshitake 1,2, Shigeharu Kinoshita1, Nahoko Bailey-Kobayashi3, Naoki Hashimoto4, Kaoru Maeyama5, Kiyohito Nagai 4, Shugo Watabe2, Tetsuhiko Yoshida3, Shuichi Asakawa1 (1. The University of Tokyo, 2. Kitasato University , 3. Institute for Advanced Sciences, TOAGOSEI CO., LTD., 4. Pearl Research Institute, K. MIKIMOTO & CO., LTD., 5. Mikimoto Pharmaceutical CO., LTD.)
[1P-753(1PS-15-07)]Development of an AI-driven next-generation drug discovery system for infectious diseases
○Yuki Otani1,2, Yasunari Wakizaka1, Daisuke Koga1, Hirofumi Aso1, Hideyuki Shimizu1,2 (1. Dept. AI Systems Medicine, Tokyo Medical and Dental Univ., 2. Grad. School of Medical and Dental Science, Tokyo Medical and Dental Univ.)
[1P-754]Development of therapeutic molecules across Blood-Brain Barrier for treatment of TBE
○Mizuki Fukuta1, Sayo Fukano2, Shintaro Kobayashi2, Naoya Maekawa3, Minato Hirano1, Satoru Konnai3,4, Kentaro Yoshii1,2 (1. Nagasaki Univ., 2. Hokkaido Univ. Laboratory of Public Health, 3. Hokkaido Univ. Department of Advanced Pharmaceutics, 4. Hokkaido Univ. Department of Disease Control, Faculty of Veterinary Medicine)
[1P-755]Cellular Landscape of Cytokine Storm in Severe Dengue
○Mohamad Alkadi1, Maika Yamashita1, Masayuki Shimojima2, Tomoki Yoshikawa2, Hideki Ebihara2, Daisuke Okuzaki1, Takeshi Kurosu2 (1. Osaka University, 2. National Institute of Infectious Diseases)
[1P-756]Treatment with CSF-1 and IL-34 induced activation of microglia and is related to the survival of West Nile virus-infected mice
○Passawat Thammahakin1, Keisuke Maezono1, Thuy Thi Ngoc Duong Thuy1, Haruto Eguchi1, Hiroaki Kariwa1, Shintaro Kobayashi1,2 (1. Lab. of Public Health, Facul. of Vet Med., Hokkaido Univ., 2. IVReD, Hokkaido Univ.)
[1P-757]Functional characterization of the antiviral E3 ubiquitin ligase MARCH8
Takuya Tada1,2, Yanzhao Zhang1,3, Dechuan Kong1,4, Michiko Tanaka1, Weitong Yao1,5, Masanori Kameoka6, Takamasa Ueno4, Hideaki Fujita7, ○Kenzo Tokunaga1 (1. Dept of Pathology, Natl Inst of Infectious Diseases, 2. NYU Grossman Sch Med., 3. Sch Publ Health, China Med Univ., 4. Joint Res Ctr for Human Retrovirus Infection, Kumamoto Univ., 5. Hubei Jiangxia Lab., 6. Dept of Public Health, Kobe Univ Grad Sch of Health Sci., 7. Fac of Pharmaceutical Sci, Nagasaki Intl Univ.)
[1P-758]Molecular basis of protozoal drug discovery for gestational protozoal infection by using BIKAKEN chemical library
○Coh-ichi NIHEI1, Hiroyasu DOI1, Masayuki Igarashi1, Nanang Rudianto Ariefta2, Yoshifumi NISHIKAWA2 (1. BIKAKEN, 2. Obihiro Univ.)
[1P-759]Chikungunya virus-neutralizing aptamer disrupts E2-mediated attachment
○Kaku Goto1, Ryo Amano1, Ayako Ichinose2, Akiya Michishita2, Michiaki Hamada2, Yoshikazu Nakamura1,3, Masaki Takahashi1,3 (1. IMSUT, 2. GSASE, Waseda Univ., 3. RIBOMIC Inc.)
[1P-760]Structural analysis of EBOV NP mutant lacking RNA-binding ability reveals RNA as a structural component required for helical NP-RNA complex formation
○Yen Ni Ng1,2, Yoko Fujita-Fujiharu1,2,3, Shangfan Hu1,2,4, Kazuya Houri1,2, Yukiko Muramoto1,2, Masahiro Nakano1,2, Yukihiko Sugita1,2,5, Takeshi Noda1,2 (1. Laboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, 2. Laboratory of Ultrastructural Virology, Graduate School of Biostudies, Kyoto University, 3. Max-Planck-Institute of Biochemistry Department of Cell and Virus Structure, 4. Department of Virology, Institute of Tropical Medicine, Nagasaki University, 5. Hakubi Center for Advanced Research, Kyoto University)
[1P-761]ZIka virus envelope protein (E152) determines cell entry ability
○Naganori Kamiyama1, Nozomi Sachi1, Sotaro Ozaka1, Yasuhiro Soga1, Yomei Kagoshima1, Supanuch Ekronarongchai1, Ryosuke Suzuki2, Takashi Kobayashi1 (1. Oita University, 2. National Institute of Infectious Diseases)
[1P-762]Development of rapid and multiplex DNA detection system for bloodstream Infection
○Saaya Shimizu1, Yoshimitsu Yanagawa1, Tomoyuki Sakai1 (1. Hitachi)
[1P-763]Amino acid substitutions that affected replication of SARS-CoV-2 Omicron variants
○Yuri Furusawa1,2, Kiyoko Iwatsuki-Horimoto3,2, Seiya Yamayoshi1,2,3,4, Yoshihiro Kawaoka1,2,3,5 (1. National Center for Global Health and Medicine Research Institute, 2. Division of Virology, Institute of Medical Science, University of Tokyo, 3. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center, 4. International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, 5. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin–Madison)
[1P-764]Is strengthening innate immunity effective against highly pathogenic avian influenza viruses?
○Satoko Kobayashi1, Shih Yuan Cheng1, Kennosuke Ichikawa2, Tenkai Watanabe1,3, Takumi Terada1, Ryo Ezaki1, Mei Matuzaki1, Yuko Uchida4, Hiroyuki Horiuchi1,3 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. The Roslin Institute, University of Edinburgh,, 3. Hiroshima University Genome Editing Innovation Center , 4. National Institute of Animal Health, NARO)
[1P-765]Analysis of canary-associated kolmiovirus reveals novel replication and evolution mechanisms of circular RNA viruses
○Mai Kishimoto1,2,3, Sakiho Imai1,3, Masayuki Horie1,2,3 (1. Graduate School of Veterinary Science, Osaka Metropolitan Univ., 2. Osaka International Research Center for Infectious Diseases, Osaka Metropolitan Univ., 3. College of Life, Environment, and Advanced Science, Osaka Prefecture Univ.)
[1P-766]Functional analysis of viral proteins using network clustering based on 3D structural similarity
○Takara Doteuchi1, Manabu Igarashi2, Daiki Koge1, Takashi Abe1 (1. Graduate School of Science and Technology, Niigata University, 2. International Institute for Zoonosis Control, Hokkaido University)
[1P-767]Establishment of a reverse genetics system of rabies virus street strain and its application to imaging analysis
○Nijiho Kawaguchi1, Yukari Itakura2, Naoto Ito3, Hirofumi Sawa1,2, Yasuko Orba1,2, Michihito Sasaki1,2 (1. IIZC., Hokkaido Univ., 2. IVReD., Hokkaido Univ., 3. Fac. of. Appl. Biol. Sci., Gifu Univ.)
[1P-768]Protective mechanisms of human monoclonal antibodies cross-reactive against antigenically divergent influenza H3HA
○Shiho Chiba1,2,3, Yoshihiro Kawaoka1,2,3,4 (1. The University of Tokyo, 2. University of Wisconsin-Madison, 3. Institute of Medical Science, the University of Tokyo, 4. National Center for Global Health and Medicine Research Institute)
[1P-769]Comparative Analysis of a New Mouse Model of Lethal Dengue Hemorrhagic Fever and an Old Model to Elucidate the Mechanism of Severe Dengue
○Takeshi Kurosu1, Yusuke Sakai1, AlKadi Mohamad2, Daisuke Okuzaki2 (1. National Institute of Infectious Diseases, 2. Osaka University Immunology Frontier Research Center)
[1P-770]The elucidation of species-specific epigenetic regulation mechanisms in malaria parasite by HME inhibitor library
○Shuto Sekizawa1,2, Tamasa Araki1,3, Yuko Umeki1, Yuki Tateishi1, Sayuri Hasegawa1, Yumiko Saito-Nakano1, Hajime Hisaeda1, Takeshi Annoura1,2 (1. Dept. of Parasitol. Nat. Inst. Infect. Dis, 2. Div. of Vet. Sci. Grad. Sch. of Agri, Tokyo Univ. Agri. Tech, 3. Res. Cen. Biosafe., Lab. Anim. Patho. Bank. Nat. Inst. Infect. Dis)
[1P-771]Frontiers in COVID-19 Patient Management: High-throughput Screening, Virus Pathogenicity, and Drug Resistance
○Yosuke Hirotsu1 (1. Genome Analysis Center, Yamanashi Central Hospital)
[1P-772]Comprehensive analysis of transposon-host chimeric RNA transcripts in various tissues from COVID-19 patients
○Hitoshi Ohtani1 (1. Nagoya university)
[1P-773]Addition of Lipids and Amino acids effect on human norovirus infection.
○Sakura Kobayashi1,2, Tsuyoshi Hayashi3, Fumihiko Hakuno1, Kosuke Murakami2 (1. Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2. Center for Emergency Preparedness and Response, National Institute of Infectious Diseases, 3. Department of Virology II, National Institute of Infectious Diseases)
[1P-774]Analysis of RtxA-Dependent Proliferation and Pathogenicity of Aeromonas hydrophila in Host Tissues
○Kohei Yamazaki1, Kei Shiraisi1, Saeko Takizawa1, Takashige Kashimoto1 (1. Vet Public Health, Kitasato Univ.)
[1P-775]Generation of recombinant giant viruses by transfection of PCR amplicon
○Hiroyuki HIKIDA1, Hiroyuki Ogata1 (1. Kyoto University)
[1P-776]Genome and transcriptome analysis of cells co-infected with hepatitis B and D viruses
○Coco Okamura1,2, Masashi Iwamoto3, Koichi Watashi3, Masamichi Muramatsu3,4, Moto Kimura1, Wataru Sugiura1, Shawichi Iwamuro2, Junko S Takeuchi1,2 (1. NCGM, 2. Toho Univ., 3. NIID, 4. KBIC)
[1P-777]An infection model for SARS-CoV-2 using rat transplanted with hiPSC-airway epithelial cells
○Masayuki Kitano1,5, Hiroe Ohnishi5, Makino Akiko2, Tatsuo Miyamoto3, Yasuyuki Hayashi5, Keisuke Mizuno5, Shinji Kaba5, Yoshitaka Kawai5, Tsuyoshi Kojima5, Yo Kishimoto5, Norio Yamamoto4,5, Keizo Tomonaga2, Koichi Omori5 (1. Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-kofukai, 2. Institute for Life and Medical Sciences, Kyoto University, 3. Department of Molecular and Cellular Physiology, Research Institute for Cell Design Medical Science, Graduate School of Medicine, Yamaguchi University, 4. Kobe City Medical Center General Hospital, 5. Department of Otolaryngology - Head and Neck Surgery, Kyoto University)
[1P-778]Enhancement of Lentiviral Vector Infectivity through the dual-pseudotyping of VSV-G and SeV-HN Envelope Proteins
○Bat-Erdene Jargalsaikhan1, Masanaga Muto1, Youngeun Been2, Shoma Matsumoto1, Eiichi Okamura1, Tadanobu Takahashi3, Yutaka Narimichi3, Yuuki Kurebayashi3, Hideyuki Takeuchi3, Takashi Shinohara4, Ryo Yamamoto5, Masatsugu Ema1,5 (1. Department of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga 520-2192, Japan, 2. Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan, 3. Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan, 4. Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan, 5. Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan)
[1P-779]Nonwoven fabrics coated with cerium oxide nanoparticles for viral inactivation and transmission inhibition.
Eisuke Umezawa1, Shota Sekiguchi2, Kan Fujino1, Masateru Ito2, ○Satoshi Taharaguchi1 (1. Azabu Univ., 2. Toray Inc.)
[1P-780]Analysis of a novel mechanism of nuclear localization for arthropod-borne Orthobunyavirus nucleoprotein
○Madoka Kawahara1, Tomoki Yoshikawa1, Kohei Oishi1, Takeshi Kurosu1, Masayuki Shimojima1, Hideki Ebihara1 (1. National Institute of Infectious Diseases)
[1P-781]Transiently senescent hepatocytes exhibit tissue repair-promoting dynamics in response to acute liver injury
○Zixue Zhang1, Yasuhiro Nakano1,2, Soichiro Kumamoto1, Yuta Moriguchi1,3, Yoshikazu Johmura1,2 (1. Cancer Res. Inst., Kanazawa Univ., 2. Inst. Front. Sci. Initiative, Kanazawa Univ., 3. Sch. Biol. Sci. Tech., Col. Sci. Engr., Kanazawa Univ.)
[1P-782]Frontotemporal dementia gene progranulin deficiency induces autoimmune liver disease via lipid metabolism dysfunction
○Chiharu Tanaka1, Siho Sakai1, Mari Gotoh2, Yasunori Miyamoto1,3, Kei Hashimoto1,3 (1. Graduate School of Humanities and Sciences, Ochanomizu University, 2. Faculty of Medical Technology, Teikyo University, 3. Institute of Human Life Science, Ochanomizu University)
[1P-783]Amyloid conformation-dependent disaggregation revealed by real-time fluorescence imaging
○Yoshiko Nakagawa1, Shingo Tamai1,2, Takashi Nomura1, Motomasa Tanaka1 (1. RIKEN, 2. Tokyo Medical and Dental University)
[1P-784]Sestrin2 ameliorates against aging induced benign prostatic hyperplasia via activation of AMPK/mTOR-mediated autophagy
○Huiju Lee1, KyungHyun Kim1, YaeJi Kim1, SungPil Cho1, JuYoung Jung1 (1. Department of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea)
[1P-785(1AS-02-05)]Non-senolytic actions of Dasatinib and Quercetin (D+Q) on senescent cells
○Koyu Ito1, Masahiro Wakita1, Birte Kristin Jung1, Eiji Hara1 (1. Osaka University)
[1P-786]Biological Age Prediction Using a Deep Neural Network Based on Steroid Metabolic Pathways
○Zi Wang1, Qiuyi Wang1, Kenji Mizuguchi1, Toshifumi Takao1 (1. IPR, Osaka Univ.)
[1P-787]Irradiation of vascular endothelial cells induces cellular senescence and extracellular release of miR-21-5p
○Keisuke Yamamoto1, Satoru Monzen2,3, Misturu Chiba1,2 (1. Department of Bioscience and Laboratory Medicine, Graduate School of Health Sciences, Hirosaki University, Hirosaki, Aomori 036-8564, Japan, 2. Research Center for Biomedical Sciences, Hirosaki University, Hirosaki, Aomori 036-8564, Japan, 3. Department of Radiation Science, Graduate School of Health Sciences, Hirosaki University, Hirosaki, Aomori 036-8564, Japan)
[1P-788]Role of Rab7 in SIRT1-mediated regulation of autolysosome formation
○Yukika Saga1, Ryusuke Hosoda1, Atsushi Kuno1 (1. Dept. of Pharmacology, Sapporo Medical Univ. School of Medicine)
[1P-789]Age-dependent impairment of protein homeostasis in Drosophila adult muscle and the suppression by sesamin: its effects on the proteasomal degradation and autophagy
○Yuka Yonezu1,2, Dat Tuan Le1, Tadashi Nomura1,2, Yoshihiro H Inoue1 (1. Biomedical Res. Ctr., Kyoto Inst. Tech., 2. Grad. Sch. of Sci. Tech., Kyoto Inst. Tech.)
[1P-790]Involvement of the mitochondrial respiratory chain in premature cellular senescence induced by the temporal inhibition of proteostasis
○Yasuhiro Takenaka1,2, Ikuo Inoue2, Masataka Hirasaki3, Masaaki Ikeda4, Yoshihiko Kakinuma1 (1. Dept. of Bioregulatory Science, Nippon Med. Sch., 2. Dept. of Diabetes and Endocrinology, Saitama Med. Univ., 3. Dept. of Clinical Cancer Genomics, Saitama Med. Univ., 4. Dept. of Physiol., Saitama Med. Univ.)
[1P-791]Screening for Ayurvedic herbs that prenvent protein aggregation.
○Sumire Watanabe1, Maiko Natsui2, Yuki Takauji2,3, Yoshimi Yamakami2, Michihiko Fujii2 (1. School of Sciense, Yokohama City Univ. , 2. Graduate School of Nanobiosciense, Yokohama City Univ. , 3. Ichibanlife Corp.)
[1P-792]The exploration of premature senescence-inducing factors commonly altered in the hepatocyte line Huh7 and hepatic stellate cell line LX-2 by exposure to inorganic arsenic using RNA-seq
○Kazuyuki Okamura1, Takehiro Suzuki1, Nobuyoshi Nakajima2, Keiko Nohara1 (1. Health and Env.Risk Div., NIES, 2. Biodiversity Div., NIES)
[1P-793(1PS-01-03)]Mitochondrial structural changes in response to nuclear DNA damage triggers cellular senescence
○Shota Yamauchi1, Hidenori Ichijo2, Akiko Takahashi1 (1. JFCR, 2. Tokyo Med. Dent. Univ.)
[1P-794]Analysis of the Regulatory Mechanism of Cellular Senescence by Proteostasis and Lamin B Receptor
○Keisuke Tanabe1, Yuki Takauji1, Haruna Miyashita1, takuma Katakawa1, Saeri Fujii1, Michihiko Fujii1 (1. Graduate school of Nanobioscience, Yokohama city Univ.)
[1P-795]Analysis of the neuronal senescence inhibition mechanism mediated by a novel DHA-binding Protein
○Nana Sakai1, Natsuki Tanaka1, Ryoto Hamamoto1, Ikuko Yao1, Michinori Toriyama1 (1. Kwansei Gakuin University)
[1P-796]Generation of knock-in mice harboring primate-specific long non coding RNA, urothelial cancer associated 1 (UCA1) with CRISPR-Cas9, and instability of UCA1 in mouse genome
Sei Kondo1, Miho Kuwahara1, Shanqi Fu1, Kavitha Panneer Selvam1, Janvier Habumugisha1, Mitsuaki Ono2, Masahiro Fujii3, Takashi Nishida1, Satoshi Kubota1, ○Takako Hattori1 (1. Dept. Biochem. Mol. Dent., Okayama Univ. Grad. Sch. Med., Dent. Pharm. Sci., 2. Dept. Mol. Bio. Biochem., Okayama Univ. Grad. Sch. Med., Dent. Pharm. Sci., 3. Deprt. Animal Resources, Adv. Sci. Res. Cent., Okayama Univ.)
[1P-797(1PS-02-06)]Regulatory mechanism of cold-inducible diapause in Caenorhabditis elegans.
○Makoto Horikawa1, Masaki Mizunuma1 (1. Hiroshima Univ., Grad. Sch. Integr. Sci. for Life, Dept. Mol. Biotech.)
[1P-798]Analysis of the local mechanism by mitochondrial stress response factor GDF15
○Tomoyoshi Fukuoh1, Yuka Nozaki1, Yuhei Mizunoe1, Masaki Kobayashi2,3, Yoshikazu Higami1,4 (1. Dept. of Pharm. Sci., Grad. Sch. of Pharm. Sci., Tokyo Univ. of Sci., 2. Dept. of Nutrition and Food Sci., Grad. Sch. of Humanities and Sci., Ochanomizu Univ., 3. Inst. for Human Life Innovation, Ochanomizu Univ., 4. Div. of Cell Fate Regul., Res. Inst. for Biomed. Sci., Tokyo Univ. of Science.)
[1P-799]Search for molecules that exhibit senolytic activity against lung tissue-derived cells
○kotoya kanemoto1, Koichiro Kawaguchi1 (1. Kyoto Institute of Technology)
[1P-800]Development of Neuronal Senescence Prevention Drugs through the Discovery of Novel SARM1 Inhibitors Using In Silico Virtual Screening
○Takumi Hamada1, Natsuki Tanaka1, Ikuko Yao1, Michinori Toriyama1 (1. Kwanseigakuin university)
[1P-801]Analysis of the molecular mechanism of nuclear receptors in aging
○Makiko Okuda1, Koichiro Kawaguchi1 (1. Kyoto Institute of Technology, Undergraduate Program of Applied Biology)
[1P-802]Increased Susceptibility to AKI in Aged Mice: Apelin's Protective Mechanisms
○Geum-Lan Hong1 (1. Chungnam National University)
[1P-803]Elucidation of the Ovarian Function of Akr1b7 Declining with Ovarian Aging
○Keishiro Isayama Isayama1, Keiji Watanabe1, Masato Ohtsuka3, Seisuke Kimura4, Murata Tomoaki2, Takeshi Honda5, Masataka Asagiri5, Shun Sato6, Hiroshi Tamura7, Norihiro Sugino6, Yoichi Miszukami1 (1. Yamaguchi Univ. Gene., 2. Yamaguchi Univ. Life Sciences., 3. Tokai Univ. Med., 4. Kyoto Sangyo Univ. Life Sciences., 5. Yamaguchi Univ. Med. Pharma., 6. Yamaguchi Univ.Med. obstetrics and gynecology., 7. Yamaguchi Prefectural Grand Medical Center.)
[1P-804]The expression of glycans in senescent vascular smooth muscle cells
○Norihiko Sasaki1, Yoko Itakura1, Masashi Toyoda1 (1. Tokyo Metropolitan Institute of Gerontology)
[1P-805]Functional significance of Calcoco1 in aging
○Haruto Shimada1, Daisuke Mashiko2, Ryuya Takemoto3, Hidetaka Kosako4, Masahito Ikawa2, Izumi Ohigashi1 (1. Division of Experimental Immunology, IAMS, Tokushima Univ., 2. Department of Experimental Genome Research, RIMD, Osaka Univ., 3. Laboratory for Embryology, IAMS, Tokushima Univ., 4. Division of Cell Signaling, IAMS, Tokushima Univ.)
[1P-806]Functional analysis of demethylase JMJD2C in the suppression of cellular senescence
○Riku Yamashita1, Taiichi Osumi1, Taiki Nagano2, Tetsushi Iwasaki1,2, Jotaro Nakanishi3, Kazuyuki Miyazawa3, Shinji Kamada1,2 (1. Department of Biology, Graduate School of Science, Kobe University, 2. Biosognal Research Center, Kobe University, 3. MIRAI Technology Institute, Business Core Technology Center, Shiseido Co., LTD)
[1P-807]Analysis of selective cytotoxicity in various cancer cell lines by sulfur including glycolipid SQAP (Sulfoquinovosyl-acyl propanediol)
○Misaki Tobashira1, Masahiko Oshige2,3, Shinji Katsura2,3, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1. Dept. of Sci. Eng., Tokyo Denki Univ., 2. Dept. of Envi. Eng. Sci., Gunma Univ., 3. GUCFW)
[1P-808]Effects of SQAP (Sulfoquinovosyl-acyl propanediol) and CoCl2 on human lung cancer cell line A549
○Keishu Yoshida1, Gakuto Horiuchi1, Airi Hori1, Masahiko Oshige1,2, Shinji Katsura1,2 (1. Dept. of Envi. Eng. Sci., Gunma Univ., 2. GUCFW)
[1P-809]Synthesis of ether-type SQAP and its biological activity in human lung cancer cell line A549
○Yukiya Yamano1, Siyori Yanagisawa1, Nayuko Akiyama2, Ayano Mouri2, Nozomi Ishii3, Ichiro Matsuo3, Masahiko Oshige1,2,4, Shinji Katsura1,2,4 (1. Dept. of Envi. Eng. Sci., School of Sci. and Tech. , Gunma Univ, 2. Dept. of Food Eng., Gunma Univ. , 3. Dept. of Mol. Sci., School of Sci. and Tech. , Gunma Univ., 4. GUCFW)
[1P-810]Mechanisms of cell death induction by targeting ROS in the novel cluster compound Ag5
○Ryo Kamata1, Toyohiro Yamauchi1,2, Hitoshi Saito1, Yuta Sakae1, Tomoko Yamamori1, Tomoyoshi Soga3, Ross Breckenridge4, Martin Treder4, Akihiro Ohashi1,2 (1. National Cancer Center, 2. University of Tokyo, 3. Keio University, 4. Arjuna Therapeutics)
[1P-811]CENP-E inhibitors activate innate immune responses and novel protein synthesis by inducing cell senescence
Ryo Kamata1, ○Kumi Kinoshita1,2, Hitoshi Saito1, Yukie Kashima2, Gaku Yamamoto1, Chiaki Mashima1, Tomoko Yamamori Morita1, Pinyi Lu3, Akihiro Ohashi1,2 (1. NCC, 2. Univ.Tokyo, 3. FNL)
[1P-812]Survival Strategy of Cancer Cells under Acidic pH Tumor Microenvironment
○Manami Hasegawa1, Keisuke Maeda2, Sho Aki1,2, Tsuyoshi Osawa1,2,3 (1. Dept. of Chem.Bio., Grad. Sch. of Eng., Univ. of Tokyo, 2. RCAST, Univ. of Tokyo, 3. Dept of Biol.Sci., Grad. Sch. of Sci., Univ. of Tokyo)
[1P-813]RNA binding protein ZCCHC24 maintains cancer stem like status in triple negative breast cancer
○Yutaro Uchida1, Ryota Kurimoto1, Tomoki Chiba1, Takahide Matsushima1, Goshi Oda2, Iichiroh Onishi3, Yasuto Takeuchi4, Noriko Gotoh4, Hiroshi Asahara1,5 (1. Institute of Science Tokyo, Department of Systems Biomedicine, 2. Institute of Science Tokyo, Department of Surgery, Breast Surgery, 3. Institute of Science Tokyo, Department of Comprehensive Pathology, 4. Kanazawa Univ., Division of Cancer Cell Biology, 5. Department of Molecular Medicine, Scripps Research)
[1P-814]CD200 induces tumor proliferation and motility by activating β-catenin signaling pathway and EMT in gastric cancer
○Hana Lee1,3, Won-Jin Kim1,3, A Reum Choi2, Seok-Jun Kim1,2,3 (1. Department of Integrative Biological Sciences & BK 21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju, Republic of Korea, 2. Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea, 3. Institute of Well-Aging Medicare & Chosun University G-LAMP Project group, Chosun University, Gwangju, Republic of Korea)
[1P-815]Bruceine D alleviated prostate cancer by inducing autophagy through the WNT/β-Catenin signaling pathway
○Yaeji Kim1, Kyunghyun Kim1, Huiju Lee1, Sungpil Cho1, Juyoung Jung1 (1. Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, Republic of Korea)
[1P-816]High GRWD1 expression predicts clinically aggressive lower grade glioma, skin cutaneous melanoma, and kidney renal clear cell carcinoma carrying wild-type p53
○Kouji Hasetsu1, Kota Kayama1, Akihiro Ooga1, Nozomi Sugimoto1, Masatoshi Fujita1 (1. Dept. of Cellular Biochem., Grad. Sch. Pharm. Sci., Kyushu Univ.)
[1P-817]O-GlcNAcylation of histone H2A promotes proliferation of triple-negative breast cancer cells via transcriptional regulation of KDM5B demethylase
Yoko Uno1, ○Koji Hayakawa1 (1. OUS, Fac of Vet, Lab of Gene)
[1P-818]Analysis of BCR-ABL drug-responsive interactions that induce chronic myeloid leukemia (CML)
○Yosei Yamauchi1, Takanori Nakamura1, Hidetaka Kosako2, Mikihiko Naito3, Tatsuya Sawasaki1 (1. Proteo-Science Center, Ehime University, 2. Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, 3. Graduate School of Pharmaceutical Sciences, The University of Tokyo)
[1P-819]The roles of METTL27 in the progression of human cancers
○Toshifumi Hara1, Tomoharu Takeuchi1 (1. Aichi Gakuin Univ.)
[1P-820(1PS-01-02)]Spatial transcriptome reveals the mechanisms underlying competitive communication between oncogenic cells and neighbors.
○Mai Miyake1, Yuki Akieda1, Yukinari Haraoka1, Kaori Tanaka2, Akihito Harada2, Yasuyuki Ohkawa2, Tohru Ishitani1 (1. Dept. of Homeostatic Regulation, RIMD, Osaka Univ., 2. Dept. of Transcriptomics, MiB, Kyushu Univ.)
[1P-821]Effects of estrogen via intracellular signaling pathways on malignancy of human lung adenocarcinoma
○Kazuya Honda1,2, Takumi Konno1, Daichi Ishi2, Yuma Shindo2, Wataru Arai2, Masahiro Miyazima2, Atsushi Watanabe2, Takayuki Kohno1, Takashi Kojima1 (1. Department of Cell Science, Institute of Cancer Research, School of Medicine, Sapporo Medical University, 2. Department of thoracic surgery, Sapporo Medical University)
[1P-822]LncRNA MANCR is involved in the malignance of mesenchymal glioma stem cells by regulating OLIG2 and CD44 expression
○Teruhide Sato1, Souichi Oe1, Taro Koike1, Shinichi Hayashi1, Ryohei Seki-Omura1, Yousuke Nakano1, Hikaru Iwashita1, Yuki Sato1, Yukie Hirahara2, Masaaki Kitada1 (1. Dept. Anat. Kansai Med. Univ., 2. Faculty of nursing Kansai Med. Univ.)
[1P-823]Functional analysis of COL6A2 in hydrogel-induced glioma stem cells
○Atsuko Takamura1,2, Masumi Tsuda2,3, Lei Wang2,3, Yoshitaka Oda2, Zen-ichi Tanei2,5, Jian Ping Gong3,4, Shinya Tanaka2,3,5 (1. Sch. of Med. Hokkaido Univ., 2. Dep. of Cancer Pathol., Fac. of Med., Hokkaido Univ., 3. WPI-ICReDD, Hokkaido Univ., 4. Lab. of Soft and Matter, Fac. of Adv. Life Science, Hokkaido Univ., 5. Dep. of Surg. Pathol., Hokkaido Univ. Hosp.)
[1P-824]Proteome analysis of adult T-cell leukemia/lymphoma (ATL): Correlation with a viral factor Tax
○Haruka Sudo1, Yasuhiro Tonoyama2, Emi Ikebe3, Hiroo Hasegawa4, Hidekatsu Iha5, Yo-ichi Ishida1 (1. Lab. Biochem., Fac. Pharm. Sci., Shonan Univ. Med. Sci., 2. Sup. Ctr. Stu. Prac. Lab., Fac. Pharm. Sci., Shonan Univ. Med. Sci., 3. Natl. Inst. Infect. Dis., 4. Dept. Lab. Med., Nagasaki Univ. Hosp., 5. Dept. Microbiol., Fac. Med., Oita Univ.)
[1P-825(1PS-15-06)]Study of anticancer and antiviral properties of several derivatives of piperazine-substituted pyranopyridines
○Sona Buloyan1, Alexander Ivanov2 (1. Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA, 2. Engelhardt Institute of Molecular Biology Russian Academy of Sciences)
[1P-826]A role of ASH2L, a core subunit of COMPASS complex, in ling cancer cells
○Akihiko Ishimura1, Hambing Lyu1, Khurelsukh Buyanbat1, Makiko Meguro-Horike2, Ryusuke Suzuki1, Shin-ichi Horike2, Hidekazu Tsutsui3, Kazuaki Ninomiya4, Seiji Yano5, Takeshi Suzuki1 (1. Div. Functional Genomics, Cancer Res. Inst., Kanazawa Univ., 2. Div. Integrated Omics Res., Inst. Liberal Art and Sci., Kanazawa Univ., 3. Biosci., Biotech., Biomed. Eng., Japan Adv. Inst. Sci. Tech. (JAIST), 4. Unit Biomass Refinery Res., Inst. Frontier Sci. Initiative, Kanazawa Univ., 5. Dept. Respiratory Med., Fac. Med., Inst. Medical Pharmaceutical and Health Sci., Kanazawa Univ.)
[1P-827]Effects of Fusobacterium infection in ovarian cancer
○Ryosuke Sonobe1, Shinya Nakano1, Miho Suzuki1, Keiko Shinjo1, Yutaka Kondo1 (1. Nagoya Univ.)
[1P-828]The mechanisms regulating the fate of tumor-initiating cells driving intratumoral cellular diversity and cancer progression
○Masaya Yamazaki1, Takatsugu Ishimoto1 (1. The Foundation For Cancer Research., Japan)
[1P-829]PSAT1-Mediated Extracellular Vesicle Drives Cancer Metastasis
○Tomofumi Yamamoto1,2,3 (1. National Institute of Health Sciences, 2. National Cancer Center Research Institute, 3. Tokyo Medical University)
[1P-830]SYTL2 promotes proliferation and metastasis of gastric signet ring cell carcinoma
○Yu-Seon Lee1,3, Woong Kim3, Seok-Jun Kim1,2,3 (1. Department of Integrative Biological Sciences & BK 21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju, Republic of Korea , 2. Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea, 3. Institute of Well-Aging Medicare & Chosun University G-LAMP Project group, Chosun University, Gwangju, Republic of Korea)
[1P-831]Galectin-3 reduces PRIM1 mediated DNA damage response to regulates drug sensitivity
○Da-Bin Choi1,2, Hyeon-Gu Kang1,2, Seok-Jun Kim1,2,3 (1. Department of Integrative Biological Sciences & BK 21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju, 61452, Republic of Korea, 2. Institute of Well-Aging Medicare & Chosun University G-LAMP Project group, Chosun University, Gwangju, 61452, Republic of Korea, 3. Department of Biomedical Science, Chosun University, Gwangju, 61452, Republic of Korea)
[1P-832]Regulation of EMT-induced transcription factor ZEB2 expression: analysis of a novel transcription start point and cell type-specific promoter activity
○Yasuyo Suzuki1, Noriko Nomura1, Kenichiro Yamada1, Shin Hayashi1 (1. Dept. of Genet., Inst. for Develop. Res., Aichi Develop. Disability Ctr.)
[1P-833]Screening and Evaluation of Sex-Specific Target Genes in Cancer
○Juyeon Kim1, Seong Cheyun1, Hyobin Bang1, Sun Young Kim1 (1. Duksung Women's Univ.)
[1P-834]Characterization of ARK5 Mutants and Elucidation of Their Mechanisms in Colorectal Cancer Malignancy
○Sae Yamaguchi1, Miki Tanabe2, Naoyuki Iida2 (1. Grad. Sch. Pharm., Kitasato Univ., 2. Sch. Pharm., Kitasato Univ.)
[1P-835]Analysis of Cell Death Induction by Short-Lived Alpha-Emitting Radionuclides
○SOICHIRO MAGARA1, KOKI MAYUSUMI1, KAZUHIRO OOE2,3, ATSUSHI TOYOSHIMA2,3, KAZUYA KABAYAMA1,2,3, KOICHI FUKASE1,2,3 (1. Dept. of Chem., Grad. Sch. of Sci., Osaka Univ., 2. FRC, Grad. Sch. of Sci., Osaka Univ., 3. Inst. for Radiation Sciences, Osaka Univ.)
[1P-836]Epithelial cells induce cell death in precancerous cells via the MHC-I interaction
○Shiyu Ayukawa1, Nagisa Kamoshita1, Takeshi Maruyama1 (1. Tokyo University of Pharmacy and Life Sciences)
[1P-837]Mutant p53 “Gain of function” Promotes Breast Cancer Malignancy by Regulating SREBP2 Nuclear Translocation
○Akitoshi Nakayama1, Masataka Yokoyama1, Naoko Hashimoto1,2, Kazuyuki Yamagata1, Tomoaki Tanaka1,2 (1. Dept. of Mol. Diag., Chiba Univ. Grad. Sch. of Med., 2. Chiba Univ. Res. Inst. of Disaster Med.)
[1P-838]Functional analysis of miRNA-X, whose expression is regulated by SAPK, in colorectal cancer.
○Noriko Tokai-Nishizumi1, Takanori Nakamura1, Mutsuhiro Takekawa1 (1. The University of Tokyo)
[1P-839]Analysis of metastasis suppression by extracellular vesicles derived from iPS cells
Noa Katayama1, Misato Nakano1, Asuka Tamura1, ○Mikako Saito1 (1. Dept. Biotechnol. Life Sci., Tokyo Univ. Agricul. Technol.)
[1P-840]Analysis of factors affecting protoporphyrin IX accumulation in photodynamic diagnosis using aminolevulinic acid
○Saki Kasai1, Shun-ichiro Ogura1 (1. Dept. of Sci. Technol., Univ of Tokyo tech (Institute of Science Tokyo))
[1P-841]Expression Profiling of Radiation Resistance-Related Transcripts in Bladder Cancer Cell Lines
Daiki Ikeda1, Mari Hara2, ○Yurika Shimizu3, Akira Yamasaki3, Takuya Tsujino4, Kazumasa Komura4, Tatsuo Ito3,1 (1. Dept. Health Informatics, Kawasaki Univ. Med. Welfere, 2. Okayama Univ. Medical School, 3. Dept. Hygiene, Kawasaki Medical School, 4. Dept. Urology, Osaka Medical and Pharmaceutical Univ.)
[1P-842]Search for structurally variable sites of natural product simplifications with anti-tumor activity
○Misaki Sato1, Tomoya Higashi1, Tomoki Hosoya1, Humiya Seki2, Tetuyuki Akasi5, Shingo Dan5, Takahiko Hara2,3,4, Nobuo Kitada1,6, Takashi Hirano1, Syojiro Maki1,7 (1. Graduate School of Informatics and Engineering, The University of Electro-Communications, 2. Tokyo Metropolitan Institute of Medical Science, 3. Tokyo Medical and Dental University, 4. School of Science, Tokyo Metropolitan University, 5. The Cancer Chemotherapy Center of JFCR, 6. Coordinated Center for UEC Research Facilities, 7. The Cancer Chemotherapy Center, The University of Electro-Communications)
[1P-843]Identification of a novel ubiquitin-proteasome pathway targeting the tumorigenic protein Skp2
○Kouhei Shimizu1, Masayuki Shiota2, Hirotaka Takahashi3, Tatsuya Sawasaki3, Fuminori Tokunaga1 (1. Dept. of Med. Biochem., Grad. Sch. of Med., Osaka Metropol. Univ., 2. Dept. of Mol. Bio. of Med, Grad. Sch. of Med., Osaka Metropol. Univ., 3. PROS, Ehime Univ.)
[1P-844]Non-apoptotic cell death induction and its susceptibility mechanism by elaiophylin in synovial sarcoma.
○Satoru Nagoyalien Sasagawa1 (1. Research Institute, Nozaki Tokushukai Hospital)
[1P-845]Transcriptome analysis of intraperitoneal cell clustering of scirrhous gastric carcinoma cells
○Makoto Miyazaki1,2, Hideki Yamaguchi2 (1. Chiba Cancer Ctr. Res. Inst., 2. Sasaki Inst., Sasaki Foundation)
[1P-846]Exploring status of Drug-Resistant Cancer Cells with scMultiome
○Yasuhiko Haga1, Ayako Suzuki1, Yutaka Suzuki1 (1. Graduate school of frontier sciences, The University of Tokyo)
[1P-847]Elucidation of transient receptor potential vanilloid 4 (TRPV4)-mediated effects on carcinogenesis mechanisms in breast cancer cells.
○Takahiro Hamoya1,2, Shingo Miyamoto1, Daisuke Iizuka2,3, Tatsuhiko Imaoka2,3, Michihiro Mutoh1 (1. Department of Molecular-Targeting Prevention Kyoto Prefectural University of Medicine, 2. Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 3. Department of Radiation Effects Research, Institute for Radiological Science, National Institutes for Quantum Science and Technology)
[1P-848]Cell survival mechanisms focusing on sulfur-containing amino acids in aggressive NK cell leukemia
○Natsumi Watanabe1, Ryo Yanagiya2, Yuji Miyatake2, Ai Kotani2 (1. Dept. of Immunol., Med., Tokai Univ., 2. RIMD, Osaka Univ.)
[1P-849]Establishment of gall bladder organoid derived from cholesteric cholelithiasis model mouse and evaluation of its usefulness
○Haru YAMAMOTO Yamamoto1, Maria Mochizuki1, Tatsuya Usui1, Kazuaki Sasaki1 (1. Laboratory of Veterinary Pharmacology, Tokyo University of Agriculture and Technology)
[1P-850]Construction of a red blood cell drug delivery system using cell resealing technology
○Yuya Kume1, Kouki Higuchi1, Yuki Taguchi2, Yutaka Miura3, Nobuhiro Nishiyama3, Masayuki Murata2, Fumi Kano4 (1. School of Life Science and Technology, Institute of Science Tokyo , 2. Institute of Science Tokyo, Institute of Integrated Research, Multimodal Cell Analysis Collaborative Research Cluster, 3. Institute of Science Tokyo, Institute of Integrated Research, Laboratory for Chemistry and Life Science, 4. Institute of Science Tokyo, Institute of Integrated Research, Cell Biology Center)
[1P-851]SKNY (SpatialKNifeY): Construction of a microenvironment analysis algorithm based on cancer cell clusters and its application to single cell spatial omics data of breast cancer
○Shunsuke A Sakai1,2, Ryosuke Nomura1,3, Satoi Nagasawa4, SungGi Chi1, Ayako Suzuki3, Yutaka Suzuki3, Shumpei Ishikawa5, Katsuya Tsuchihara1,2, Shun-Ichiro Kageyama6, Riu Yamashita1,3 (1. Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 2. Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 3. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 4. Department of Breast Surgery, National Cancer Center Hospital East, 5. Division of Pathology, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, 6. Department of Radiation Oncology, National Cancer Center Hospital East)
[1P-852]Development of innovative therapeutic technology for drug resistant cancer by nuclear-targeting DDS
○Souma Kawashima Kawashima1, Koji Nagahama2 (1. Graduate school of Konan University FIRST, 2. Konan University FIRST)
[1P-853]Altered gene expression in radioresistant lung cancer cell lines
Mei Ishikawa1, Kazato Takeuchi1, Keisuke Yamamoto2, Kana Matsumoto2,3, Satoru Monzen3,4, ○Mitsuru Chiba1,3 (1. Dep. Med. Tech., School Health Sci., Hirosaki Univ., 2. Dep. Biosci. Laboratory Med., Grad. School Health Sci., Hirosaki Univ., 3. Research Cent. Biomed. Sci., Hirosaki Univ., 4. Dep. Radiat. Sci., Grad. School Health Sci., Hirosaki Univ.)
[1P-854(1AS-14-05)]ANGPTL2 in cancer: orchestration of tumor immune microenvironment
○Haruki Horiguchi1, Yuichi Oike1 (1. Kumamoto Univ.)
[1P-855]Contribution of DACH1 expression in tumor endothelial cells to tumor growth
○Takumi Shimbori1, Ryuki Nishimura2, Koki Sato2, Minori Ozaki2, Haruko Hayasaka1,2,3 (1. Dept. Sci., Grad. Sch. Sci. Eng., Kindai Univ., 2. Dept. Life Sci., Fac. Sci. Eng., Kindai Univ., 3. Res. Inst. of Sci. and Tech., Kindai Univ.)
[1P-856]Paneth-like cells produced from OLFM4+ stem cells support OLFM4+ stem cell growth in advanced colorectal cancer
Mizuho Sakahara1, ○Ryoji Yao1, Tetsuo Noda2 (1. Dept. Cell Biol., Cancer Institute, JFCR, 2. Director's office, Cancer Institute, JFCR)
[1P-857]The microRNA from exosomes in the blood of lung RFA patients that promotes cancer cell proliferation
○Yutaka Hirata1, Haruyuki Takaki2, Reona Wada2, Hiroshi Kodama2, Eisuke Ueshima3, Toshiro Saito1, Koichiro Yamakado (1. Dept. of Physiology, Hyogo Med. Univ., 2. Dept. of Radiology, Hyogo Med. Univ., 3. Dept. of Radiology, Kobe Univ.)
[1P-858(1PS-06-04)]Development of the amido-bridged nucleic acid-modified antisense oligonucleotide targeting MCM8 as a cancer-specific chemosensitizer for platinum compounds
○Yuki Uchibori1, Masaki Suekuni1, Yuko Kokaji1, Kazumasa Yoshida1, Yuuya Kasahara2,3, Masatoshi Fujita1 (1. Grad. Sch. Pharm. Sci., Kyushu Univ., 2. NIBIOHN., 3. Grad. Sch. Pharm. Sci., Osaka Univ.)
[1P-859]Radiation carcinogenesis from the viewpoint of combined exposures: Elucidation of carcinogenic mechanisms that change with exposure order
○Yoshiko Amasaki1, Atsuko Ishikawa1, Kazuhiro Daino1, Shang Yi1, Chizuru Tsuruoka1, Yoshiya Shimada2, Shizuko Kakinuma1, Takamitsu Morioka1, Tatsuhiko Imaoka1 (1. National Institutes for Quantum Science and Technology (QST) , 2. Institute for Environmental Sciences)
[1P-860]α-Parvin Expression in Breast Cancer Tissues: Correlation with Clinical Parameters
○Midori Takeda1,2, Tohru Tezuka1, Hiroaki Ito3, Akihiko Yoshizawa4, Minsoo Kim1 (1. Kyoto Univ., 2. Kyushu Univ., 3. Kyoto Univ. Hosp., 4. Nara Medical Univ.)
[1P-861]Deciphering FGFR2-IIIb/-IIIc isoform switching in advanced cancer through whole-transcriptome sequencing
○Naoko Iida1, Tadayoshi Hashimoto1,2, Takao Fujisawa1,3, Shigenori Kadowaki4, Makoto Ueno5, Shogen Boku6, Norio Nonomura7, Eiji Oki8, Yoshito Komatsu9, Akitaka Makiyama10,11, Chigusa Morizane12, Toshihiro Kudo13, Naoki Takahashi14, Taro Shibuki1,15, Mitsuho Imai1, Riu Yamashita16, Yoshiaki Nakamura1,2, Hideaki Bandou1,2, Yoshino Takayuki2 (1. Translational Research Support Office, National cancer center of Japan, East hospital, 2. Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan, 3. Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan, 4. Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan, 5. Department of Gastroenterology, Kanagawa Cancer Center, Yokohama, Japan, 6. Department of Clinical Oncology, Kansai Medical University Hospital, Osaka, Japan, 7. Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan, 8. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 9. Department of Cancer Center, Hokkaido University Hospital, Sapporo, Japan, 10. Cancer Center, Gifu University Hospital, Gifu, Japan, 11. Center for One Medicine Innovative Translational Research, Gifu University, Gifu, Japan, 12. Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan, 13. Department of Medical Oncology, Osaka International Cancer Institute Osaka Prefectural Hospital Organization, Osaka, Japan, 14. Department of Gastroenterology, Saitama Cancer Center, Saitama, Japan, 15. Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan, 16. Division of Translational Informatics, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Japan)
[1P-862]Molecular subtypes of rat mammary cancer and their association with environmental exposures
○Tatsuhiko Imaoka1, Yukiko Nishimura1, Daisuke Iizuka1, Masaru Takabatake2,1, Kazuhiro Daino1, Mayumi Nishimura1, Takamitsu Morioka1, Yoshiya Shimada3, Shizuko Kakinuma1 (1. National Institutes for Quantum Science and Technology, 2. Tokyo Metropolitan University, 3. Institute for Environmental Sciences)
[1P-863(1PS-05-06)]SIGLEC7 in NK cells is an immune checkpoint receptor for VSIG4
○Yutaka Kasai1,2, Yuki Azuma2, Mai Mizusawa2, Yota Mitobe2, Miko Komiya1,2, Yumi Tsuboi2, Takeshi Ito3,2, Yoshinori Murakami1,2 (1. Dept. Mol. Biol., Inst. Adv. Med. Sci., Nippon Med. Sch., 2. Div. Mol. Pathol., Inst. Med. Sci., Univ. Tokyo, 3. Sect. Med. Oncol., Dept. Intern. Med., Yale Sch. Med.)
[1P-864]Mechanism of immunogenic cell death induction by a naturally occurring compound GTN057
○Himari Yamada1,2, Taisei Fujinami1, Haruka Tamatsu1, Yutaka Suto3, Yusuke Yamamoto2, Maiko Matsushita1 (1. Keio University, 2. National Cancer Center Research Institute, 3. Takasaki University of Health and Welfare)
[1P-865]Application of bispecific antibodies against human cancer antigen EGFR and T cell antigen CD3 generated by a cell fusion method
○Akane Oyama1, Takeshi Nakanishi1, Taro Tachibana1, Chikako Yokoyama1 (1. Osaka Metro. Univ.)
[1P-866]The Novel Link between Gene Expression Profiles of Adult T-Cell Leukemia/Lymphoma Patients’ Peripheral Blood Lymphocytes and Ferroptosis Susceptibility
○Yu Wang1, Hidekatsu IHA1,2 (1. Department of Microbiology, Faculty of Medicine,Oita University, 2. Division of Pathophysiology, The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID), Oita University Faculty of Medicine,)
[1P-867]Efficacy and Mechanism of Acyclic Retinoids in the Treatment of Hepatocellular Carcinoma
○Noriyoshi Tanaka1, Kota Tonegawa1, Naoki Hirokawa1, Nanako Kato2, Yoshitomo Suhara1,2, Ichiro Yajima1,2 (1. Department of Bioscience and Engineering, College of Systems Engineering and Sciences, Shibaura institute of Technology Graduate School of Engineering and Science, 2. Department o Bioscience an Engineering, Shibaura Institute of Technology of System Engineering and Science)
[1P-868]Spatial transcriptomics and whole-exome sequencing to understand drug resistance mechanisms to PARP inhibitor in high-grade serous ovarian cancer
○Hironori Suzuki1,2, Akira Yokoi1, Kosuke Yoshida1, Kazuhiro Suzuki1, Hiroaki Kajiyama1, Yusuke Yamamoto2 (1. Nagoya Univ., 2. Natl. Cancer Ctr. Res. Inst.)
[1P-869]Prediction of resistance mutations against Zotizalkib and Gilteritinib in second-line therapy for ALK-positive lung cancer
○Yuki Takei1, Chisaki Arai1, Yuta Doi1, Kentaro Semba1,2 (1. Sch. of Adv. Sci. & Eng., Waseda Univ., 2. Translational Research Center, Fukushima Medical Univ.)
[1P-870]DNA methylation and APOBEC cause acquisition of drug-resistance mutation in lung cancer
○Yosuke Seto1, Naoya Fujita2, Makoto Nishio3, Ryohei Katayama1 (1. Div. Exp. Chemother., Cancer Chemother. Ctr., JFCR, 2. Cancer Chemother. Ctr., JFCR, 3. Dept. Thorac. Med. Oncology, Cancer Inst. Hosp., JFCR)
[1P-871]The p53-p53PAD5 pathway promotes tumorigenesis in hepatocarcinoma
○Musashi Kagaya1,2, Naoya Kobayashi3,2, Krishnaraj Jayaraman2, Tatsuki Yamamoto2,4, Kiyono Aoki2, Tomoko Tazima2, Yukiko Sakaguti2, Yuko Tabata2, Daisuke Shiokawa5, Masahiro Yamamoto6, Takuya Matsuo1, Rieko Ohoki2 (1. Kitasato University, 2. National Cancer Center, 3. Tokyo Medical and Dental University, 4. Chiba University, 5. Ehime University, 6. Kumamoto University)
[1P-872]Development of novel photosensitizing dyes exerting excellent anti-tumor effects by near-infrared light with high tissue transmittance
○Toshiyuki Goto1,2, Sally Danno1,2, Chie Ueda1,2, Yosky Kataoka1,2 (1. STIN, Kobe Univ., 2. RIKEN, BDR)
[1P-873]Research for immune response pathway related molecules following cancer radiation therapy
○Junko Zenkoh1, Yutaka Suzuki1, Ayako Suzuki1 (1. Grad. Sch. of Front. Sci., Univ. of Tokyo)
[1P-874]Enhancing the Immunogenicity of Wilms Tumor 1 Epitope in Mesothelioma Cells with Immunoproteasome Inhibitors
○Masaki Ito1,7, Koido Shigeo2, Takeo Iwamoto3, Soyoko Morimoto4, Fumihiro Fujiki5, Haruo Sugiyama6, Kazuma Kiyotani7,8, Kiyotaka Shiba9 (1. Institute of Clinical Medicine and Researc, The Jikei University School of Medicine, 2. The Division of Gastroenterology and Hepatology, The Jikei University School of Medicine, 3. Core Research Facilities, The Jikei University School of Medicine, 4. Department of Cancer Stem Cell Biology, Osaka University Graduate School of Medicine, 5. Department of Cancer Immunotherapy, Osaka University Graduate School of Medicine, 6. Department of Cancer Immunology, Osaka University Graduate School of Medicine, 7. Cancer Precision Med Ctr, JFCR, 8. Lab Immunogenomics, NIBIOHN, 9. Cancer Institute, JFCR)
[1P-875]Evaluation of MSCs as vehicles for oncolytic viruses and the influence of their tissue sources on anti-tumor efficacy.
○Makoto Sukegawa1,2,3, Yoshitaka Miyagawa1, Yoshiyuki Yamazaki1, Seiji Kuroda1, Motoko Yamamoto1, Kumi Adachi1, Nobuhiko Taniai2, Hiroshi Yoshida3, Akihiro Umezawa4, Mashito Sakai1, Takashi Okada5 (1. Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan, 2. Department of Gastrointestinal Surgery, Nippon Medical School Musashikosugi Hospital, Kawasaki, Japan, 3. Department of Surgery, Nippon Medical School, Tokyo, Japan, 4. Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, Japan, 5. Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan)
[1P-876]Evaluation of clinical potential of targeted sequencing through mutational signature simulation
○Keisuke Kodama1, Yiwei Ling1,2, Hiroshi Ichikawa3, Toshifumi Wakai3, Shujiro Okuda1,2 (1. Division of Bioinformatics, Niigata University Graduate School of Medical and Dental Sciences, 2. Medical AI Center, Niigata University School of Medicine, 3. Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences)
[1P-877]Investigation of tissue-specific markers expressing at ileocecal junction
○Togo Ikuta1 (1. Saitama Cancer Center)
[1P-878]Anti-angiogenesis effects of tomato lectin for colorectal cancer
○Chizuru Sone1, Yoko Nakanishi2, Yukari Hirotani2, Nao Shioji1, Shinobu Masuda2, Kayoko Sasaki-Fukatsu1 (1. Dept. of Food Sci. Nutr., Grad. Sch. of Home Ec., Kyoritsu Wom. Univ., 2. Div. of Onco. Pathol., Dept. of Pathol. and Microbiol., Nihon Univ. Sch. of Med.)
[1P-879]Relationship between hypoxic response and glucose transporter 1 and 3 expression in colorectal cancer
○Nao Shioji1, Chizuru Sone1, Yoko Nakanishi2, Shinobu Masuda2, Kayoko Sasaki-Fukatsu1 (1. Lab. of Nutr., Dept. of Food Sci. Nutr., Fac. of Home Ec. (Grad. Sch. of Home Ec.), Kyoritsu Wom. Univ., 2. Div. of Onco. Pathol., Dept. of Pathol. and Microbiol., Nihon Univ. Sch. of Med.)
[1P-880]Reversible histone deacetylase activity catalyzes lysine acylation
○Takeshi Tsusaka1, Mohd. Altaf Najar2, Benjamin Schwarz3, Eric Bohrnsen3, Juan A. Oses-Prieto1, Christina Lee4, Alma L. Burlingame1, Catharine M. Bosio3, George M. Burslem2, Emily L. Goldberg1,5 (1. University of California San Francisco, 2. University of Pennsylvania, 3. National Institute of Allergy and Infectious Diseases, 4. University of California Berkeley, 5. Chan-Zuckerberg Biohub)
[1P-881]Bioprotective role of cold-induced lipid accumulation in renal tubular cells
○KIE HORIOKA1,2, HIROKI TANAKA3, AKIRA HAYAKAWA4, YOICHIRO TAKAHASHI2, KATJA PORVARI1 (1. Univ of Oulu, 2. Univ of Tsukuba, 3. Asahikawa Med Univ, 4. Akita Univ)
[1P-882]MED1 confines M2 polarization of subcutaneous adipose tissue macrophages in mice fed high fat diet
○Chisaki Nakamura1, Hanayo Watanabe1, Momoka Sawada1, Manaka Fujieda1, Koya Kawaguchi1, Ayana Ueno1, Miyu Yoshimura1, Ayu Muranaka1, Asuka Tanaka1, Kazuki Tsutsui1, Hikaru Tsutsumi1, Robert G Roeder2, Natsumi Hasegawa1, Mitsuhiro Ito1,2 (1. Medical Biophysics, Kobe Univ., 2. Biochem. & Mol. Biol. the Rockefeller Univ.)
[1P-883]The effects of 6-Methylsulfinylhexyl Isothiocyanate (6-MSITC), a component of wasabi, on age-related abnormalities in triglyceride metabolism
○Manami Higa1, Takenari Sato2, Keisuke Yoshikiyo1,2, Kazuhisa Watanabe3, Hidehisa Shimizu1,2 (1. Grad. Sch. Nat. Sci. Tech, Shimane Univ., 2. Fac. Life. Envi. Sci, Shimane Univ., 3. Fac. Nutr, Tokyo Kasei Univ.)
[1P-884]Stress response mechanism through lipid transport in Drosophila male accessory gland
○Chisato Shirakashi1, Shinichi Otsune1, Mirai Matsuka1, Hideki Nakagoshi1 (1. Grad. Sch. Envir. Life Natl. Sci. Tech., Okayama Univ.)
[1P-885]Development of intracellular oxygen consumption assay using novel phosphorescent oxygen probes
○Naoko Yamamoto1, Masakazu Nakakubo1, Munetaka Ishiyama1, Toshitada Yoshihara2 (1. Dojindo Laboratories, 2. Div. of Mol. Sci., Grad. Sch. of Sci. Tech., Gunma Univ.)
[1P-886]A persistent hypertension model developed on the AGT humanized mice
○Zhong Chen1, Xinyi Wu1, Wen Xie1, Tong Lin1, Dan Wang1, Juan Liang1 (1. GemPharmatech Co., Ltd.)
[1P-887]BRX deficiency prevents high-fat diet induced obesity and metabolic syndrome by reducing visceral fat inflammation
○You Lee Son1, Kondo Toru1 (1. Hokkaido University)
[1P-888]GR-KLF15 pathway controls hepatic lipogenesis during fasting.
○Yoshinori Takeuchi1, Zahra Mehrazad Saber1, Samia Karkoutly1,2, Duhan Tao1,2, Chen Ye1,2, Rika Saikawa1, Yuichi Aita2, Yuki Murayama2, Akito Shikama2, Yukari Masuda5, Yoshihiko Izumida4, Yasushi Kawakami3, Hitoshi Shimano3, Naoya Yahagi1,2 (1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical Univ., 2. Nutrigenomics Research Group, Institute of Medicine, Univ. of Tsukuba, 3. Department of Internal Medicine (Endocrinology and Metabolism), Institute of Medicine, Univ. of Tsukuba, 4. Department of Endocrinology and Diabetes, Saitama Medical Center, Saitama Medical Univ., 5. Department of Internal Medicine, Graduate School of Medicine, Univ. of Tokyo)
[1P-889]Absence of ZFP90 aggravates obesity-related non-alcoholic fatty liver disease through immune dysregulation
○Seongjoon Park1, Toshimitsu Komatsu1, Isao Shimokawa1 (1. Nagasaki University)
[1P-890]Roles of Receptor Activity-Modifying Proteins RAMP1 and RAMP3 in Adipocyte Differentiation and Lipolysis
○Marina Hayashi1,3, Takayuki Sakurai1,2, Onishi Naho1,3, Kamiyoshi Akiko1,2, Tanaka Megumu1,2, Ichikawa-Shindo Yuka1, Yunlu Zhao1, Yorisige Matuda1, Yan Zhang1, Qianqian Guo1, Peixuan Li1, Ken Hoshiyama1, Jiake Li1, Jun Duan1, Takayuki Shindo1,2 (1. Shinshu Univ. Sch.Med. , 2. Shinshu Univ. Inst.Biomed.Sci., 3. Shinshu Univ. Grad.Med.)
[1P-891]Mitochondrial redox stress under hypoxia promotes collagen synthesis in fibroblasts.
○Takayuki Isagawa1,2, Daigo Sawaki3,4, Shigeru Sato1, Tatsuyuki Sato1, Takahiro Kuchimaru1, Hiroki Sugimoto1, Chuluun-Erdene Ariunbold1, Kazutoshi Ohno5, Takahide Kohro2, Norihiko Takeda1,6 (1. Div.Cardio&Metab ,CMM, Jichi.Univ., 2. Data. Sci. Ctr, Jichi.Univ., 3. Div.Clin.Pham, Jichi. Univ, 4. Div.Comm. & Med., Jichi. Univ, 5. Div. Nephrol ., Jichi. Univ, 6. Grad. Sch. Cardol., Univ. Tokyo)
[1P-892]Analysis of the Mechanism Promoting Microbial Growth by Addition of Fluorinated Inert Solvents with a Focus on Iron
○Katsuaki Izawa1, Ryosuke Hosoki1, Yoshihisa Yamashige2, Koji Kawada1, Masafumi Hidaka1, Yukako Oma1, Shojiro Kikuchi3, Yuichi Ogawa2, Hiroyuki Setoyama4, Ichiro Hirosawa4, Masahiko Harata1 (1. Graduate School of Agricultural Science, Tohoku University, 2. Graduate School of Agriculture, Kyoto University, 3. Institute of Advanced Medical Sciences, Hyogo Medical University, 4. SAGA-LS)
[1P-893]Methyltransferase COQ5 is key-enzyme in vitamin K conversion reaction
○Nakagawa Kurumi1, Kohei Murata1, Syunta Sudo2, Yoshitomo Suhara1,2, Yoshihisa Hirota1,2 (1. Graduate School of Engineering and Science, Shibaura Institute of Technology, 2. Department of Life Science, Shibaura Institute of Technology)
[1P-894]The mechanisms of cell-to-cell signaling through the non-canonical function of secretory control by insulin receptor substrate (IRS)-2
○Ayaka Takahashi1, Hiroki Nishi1,2, Yuka Toyoshima3, Fumihiko Hakuno1, Shin-Ichiro Takahashi1 (1. Dept. of Anim. Resour. Sci., Grad Sch. of Agric. and Life Sci., Univ. of Tokyo , 2. Div. of Life Sci., Grad Sch. of Sci. and Eng., Saitama Univ., 3. Dept. of Agrobiol. and Bioresour., Sch. of Agric., Utsunomiya Univ.)
[1P-895]Evaluation of Inhibition of Ferroptosis by Vitamin K Homologues and Their Derivatives for the Treatment of Alzheimer's Disease
○Rina Watanabe1, Ayaka Kato2, Chikara Kato3, Takekoshi Susumu4, Yoshitomo Suhara1,2, Yoshihisa Hirota1,2 (1. Department of Bioscience and Engineering, College of Systems Engineering and Science, Shibaura Institute of Technology, 2. Department of Bioscience and Engineering, Shibaura Institute of Technology, 3. College of Agriculture, Academic Institute, Shizuoka University, 4. Department of Cell Biology, Tokai University School of Medicine)
[1P-896]Examining the Effects of Chronic Restraint Stress on Blood Glucose Levels
○Kisara Ueda1, Akira Toda1, Koki Daido1, Xu Li1, Futoshi Furuya1, Eri Mukai1 (1. Ritsumeikan University Graduate School of Life Science)
[1P-897]Caloric restriction-induced metabolic remodeling requires maintaining mitochondrial quality in white adipose tissue
○Jun Hasumi1, Yuka Nozaki1, Yuhei Mizunoe1, Masaki Kobayashi2, Yoshikazu Higami1,3 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Faculty of Core Research Natural Sciences Division, Ochanomizu University, 3. Research Institute for Biomedical Sciences, Tokyo University of Science)
[1P-898]Analysis of changes in myofiber type in skeletal muscle induced by low lysine diet feeding
○Reona Maezawa1, Yuki Goda1,2, Ryosuke Okino1,2, Ruri Iwai1, Takeshi Nishijima3, Ryuki Tuchida3, Yusuke Ono2, Hiroki Nishi4, Daisuke Yamanaka5, Shin-Ichiro Takahashi1, Fumihiko Hakuno1 (1. Dept. of Anim. Res. Sci., Grad. Sch. of Agri. and Life Sci., the Univ. of Tokyo, 2. Res. Team for Aging Sci.,Tokyo Metropolitan Inst. for Geriatrics and Gerontology, 3. Dept. of Health Promotion Sci., Grad. Sch. of Human Health Sci., Tokyo Metropolitan Univ., 4. Dept. of Reg. Biol., Grad. Sch. of Sci. & Eng., Saitama Univ., 5. Dept. of Vet. Med. Sci., Grad. Sch. of Agri. and Life Sci., the Univ. of Tokyo)
[1P-899(1AS-05-08)]mRNA turnover mediated by RNA modification regulates pancreatic β cell homeostasis
○Yuki Tara1, Hirotatsu Imai2, Akio Yamashita2, Tadashi Yamamoto1 (1. Okinawa Institute of Science and Technology Graduate University, 2. University of the Ryukyus)
[1P-900]RNA-seq analysis of liver mitochondria purified from mouse models of metabolic disease.
○Nanao Shirono Shirono1,2, Miwako Homma1, Yoshimi Homma3 (1. Department of Biomolecular Sciences, Fukushima Medical Univ. Sch. of Medicine, 2. Cmic Co., Ltd., 3. General South Tohoku Hospital)
[1P-901]Ambra1-mediated regulation of lipid metabolism and insulin signaling
○Tomohiro Kashikawa1, Hisako Akatsuka1, Takehito Sato1,2 (1. Dept. of Immunol.,Sch. of Med.,Tokai Univ., 2. Faculty of Nursing, Soka Univ.)
[1P-902]Exploration and functional analysis of Mebyo genes derived from TSOD mouse using Drosophila melanogaster
○Kaisei Ito1, Yingjie Jin2, Kazutaka Akagi3, Keiichi Koizumi3 (1. Dept. of Pharma. Sci.,univ.of Toyama, 2. Graduate school of Pharma-medical sciences.,univ of Toyama, 3. Inst. of Nat. Med., Univ. of Toyama)
[1P-903]Alteration of gut microbiota and suppression of ethanol-induced enteritis induced by intake of sesame-derived compounds
○Daiki Oikawa1, Hideo Ohira2, Yuichi Aoki3, Kunio Kiyomoto4, Toru Nakayama5 (1. Grad. Sch. of Biost., Kyoto Univ., 2. Fac. of Nutr., Kobe Gakuin Univ., 3. ToMMo, Tohoku Univ., 4. Kiyomoto Co., Ltd., 5. Grad. Sch. of Eng., Tohoku Univ.)
[1P-904]The study of reducing triglyceride contents by Kuwai extract ingredients
○Yuna Yamamoto1, Mia Okada1, Hinata Suzukawa1, Kirika Nakai1, Miya Ishijima1, Haruhiko Sakiyama1 (1. Senri Kinran Univ.)
[1P-905]The study on the potential antioxidant effects of Kuwai extracts
○Mai Yoshidomi1, Nao Terashita1, Kaho Sawada1, Miya Ishijima1, Haruhiko Sakiyama1 (1. Senri Kinran Univ.)
[1P-906]The role of activating transcription factor (ATF5) in mouse proximal renal tubule
○Yuri Takazawa1, Haruo Nakano1, Yuta Ichino1, Mariko Umemura1, Shigeru Takahashi1, Yuji Takahashi1, Yasuhiro Shinkai1 (1. Tokyo University of Pharmacy and Life Sciences)
[1P-907]Functional analysis of Dve in Drosophila muscle cells
○Miku Shiroo1, Taichi Urabe1, Hideki Nakagoshi1 (1. Grad. Sch. Envir. Life, Natl. Sci. Tech., Okayama Univ.)
[1P-908]Accumulation of branched-chain keto acids exacerbates blood glucose level after glucose loading
○Koki Daido1, Daichi Fuchisawa1, Shun Sugahara1, Kisara Ueda1, Akira Tohda1, Futoshi Furuya1, Shinsuke Mohri1, Eri Mukai1 (1. Ritsumeikan University)
[1P-909]Termite royal food: uncovering the special food of long-lived kings and queens
○Eisuke Tasaki1,5, Yuki Mitaka2,5, Yutaka Takahashi3, A.S.M. Waliullah3, Zinat Tamannaa3, Takumi Sakamoto3, Ariful Islam3, Masaki Kamiya3, Tomohito Sato3, Shuhei Aramaki3, Kenji Kikushima3, Makoto Horikawa3, Katsumasa Nakamura4, Tomoaki Kahyo3, Mamoru Takata5, Mitsutoshi Setou3, Kenji Matsuura5 (1. Niigata Univ., 2. Nagoya Univ., 3. Hamamatsu Med. Univ., Dep. of Cellular & Molecular anatomy, 4. Hamamatsu Med. Univ. Dep. of Radiation Oncology, 5. Kyoto University)
[1P-910]Involvement of Nrf2 in insulin secretion under glucolipotoxic condion
○Kaho Saito1, Yuta Kato1, Taiyou Yoshibe1, Ryoya Yamamoto1, Eri Mukai1 (1. Ritsumeikan University Graduate School)
[1P-911]Exon skipping therapy models for rare disease using TiD system
○Miyu Asari1, Takeki Ito1, Ryuya Watanabe1, Satoshi Kidokoro1, Naoki Wada2, Keishi Osakabe2, Yuriko Osakabe1 (1. Sch. of Life Sci. & Tech., Science Tokyo., 2. Grad. Sch. of Tech., Ind. & Soc. Sci., Tokushima Univ.)
[1P-912]Development of genetic markers related to fertility in Japanese Black bulls
○Masashi Kinukawa1, Susumu Haruta1, Atsushi Ogino1, Kazuhito Kurogi1, Yousuke Naniwa1, Kyoko Uchiyama1, Masahiko Ito2 (1. LIAJ, 2. HUSM)
[1P-913]Identification of pathological progression factors in mitochondrial cardiomyopathy using single cell transcriptomics analysis.
○Tasneem Qaqorh1, Yasunori Shintani1 (1. National cerebral and cardiovascular center)
[1P-914]A point mutation in mitochondrial DNA tRNALeu(UUR) induces brain dysfunction in mice
○Daiki Miyata1, Kaori Ishikawa1,2, Satoko Hattori3, Haruna Tani4, Takayoshi Kuriyama1, Fanyan Wei4, Tsuyoshi Miyakawa5, Kazuto Nakada1,2 (1. Grad. Sch. of Sci. and Tech., Life and Earth Sci., Biol. Prog., Univ. of Tsukuba., 2. Inst. of Life & Env. Sciences., Univ. of Tsukuba., 3. Res. Creation Support Ctr., Aichi Med. Univ., 4. Dept. of Modomics Biol. & Med., IDAC, Tohoku Univ., 5. Div. of Systems Med. Sci., Inst. for Comprehensive Med. Sci., Fujita Health Univ.)
[1P-915]Model mice of hereditary hearing loss DFNA78 and species-specific splicing property of the causative gene, SLC12A2
○Hideki Mutai1,2, Saki Ichikawa3,4,5, Yukiko Kuroda6, Shinobu Noji6, Koichi Matsuo6, Satoshi Tanaka3, Naoyuki Kataoka3, Masato Fujioka1, Tatsuo Matsunaga2,7 (1. Molecular Genetics, Kitasato University School of Medicine, 2. National Institute of Sensory Organs, NHO Tokyo Medical Center, 3. Lab. Cellular Biochemistry, Department of Animal Resource Sciences/ Veterinary Medical Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 4. Dept. Biophysics and Biochemistry, Faculty of Science, The University of Tokyo, 5. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 6. Lab. Cell and Tissue Biology, Keio University School of Medicine, 7. Center of Clinical Genetics, NHO Tokyo Medical Center)
[1P-916]Exploring the molecular pathogenesis of ribosomopathies using zebrafish disease models
○Tamayo Uechi1, Mariko Nagatomo1, Yukari Nakajima1, Yutaka Suzuki2, Naoya Kenmochi1 (1. Univ. of Miyazaki, 2. Tokyo Univ.)
[1P-917]Development of a model mouse for pediatric mitochondrial disease associated with Isoleucyl-tRNA synthetase gene mutations.
○Masaki Watanabe1, Nobuya Sasaki1 (1. Laboratory of Laboratory Animal Science and Medicine, School of Veterinary Medicine, Kitasato University.)
[1P-918]Dystrophin Dp71bΔ73 is a novel specific isoform of Dp71 in Retinoblastoma
○Suzuri Okamoto1, Atsuko Takeuchi1, Tomoko Horiguchi1, Aiko Sunami1, Kayo Osawa1, Yusuke Ohkame2, Yasuhiro Kazuki2, Masafumi Matsuo1,3 (1. Kobe Tokiwa Univ., 2. Tottori Univ., 3. Kobe Univ.)
[1P-919]Elucidation of the molecular mechanism of microtubule dynamics by dynamin-2 in Charcot-Marie-Tooth disease
○Yuki Miki1, Misako Okumura1, Takahiro Chihara1, Kozue Hamao1 (1. Biomedical sci., Grad. Sch. of Integr. Sci. Life., Univ. of Hiroshima)
[1P-920]Establishment of iPS cells derived from patients with dilated cardiomyopathy with LMNA gene truncation mutation and analysis of differentiated cardiomyocytes.
○Maya Takeo2,1, Nobuyuki Murakoshi2, Dongzhu Xu2, Yuzuno Shimoda2, Tomoko Ishizu2 (1. University of Tsukuba, Graduate School of Comprehensive Human Sciences, 2. University of Tsukuba, cardiovascular medicine laboratory)
[1P-921]Male infertility gene Kansl1l is expressed in multiple organs and may cause ciliopathy
○Tomoko Kagiya1, Shunji Itoh2, Ikuji Hatamura2 (1. Fac. of Medical tech., Dept. of Health Sci., Kansai Univ. of Health Sci., 2. Dept. of Health Sci., Grad. Sch., Kansai Univ. of Health Sci.)
[1P-922]Modeling Malignant Peripheral Nerve Sheath Tumor Progression Using iPS Cells from Neurofibromatosis Type 1 Patients
○Aoba Nakajima1, Eiji Nakata2, Taro Osawa1, Daisuke Yamada1, Masyu Futagawa3, Tomoka Takao1, Akira Hirasawa3, Toshifumi Ozaki2, Takeshi Takarada1 (1. Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2. Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 3. Department of Clinical Genetics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)
[1P-923]Deficiency of TASL aggravates rheumatoid arthritis by promoting Th17 cell differentiation and osteoclastogenesis
○Soyeon Jang1, Hyeong-soo Kim1, Zae Young Ryoo2 (1. Institute of Life Science and Biotechnology, Kyungpook National University, Daegu 41566, Republic of Korea, 2. School of Life Science, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea)
[1P-924]Characterization of disease-specific alterations in metabolites and effects of mesenchymal stromal cells on dystrophic muscles
○Yuko Nitahara Kasahara1, Guillermo Herrera Posadas1, Yuko Aizen1, Yuji Yamanashi2, Takashi Okada1 (1. Div. of Mol. Med. Genetics, Inst. of Medical Science, Univ. of Tokyo., 2. Div. of Genetics, Inst. of Medical Science, Univ. of Tokyo.)
[1P-925]Co-localization analysis of stomatal movement regulation factor PATROL1 and cortical microtubules in guard cells and pavement cells.
○Moeka Adachi1, Kou Iba2, Takumi Higaki1 (1. Faculty of Sci., Kumamoto Univ., 2. Faculty of Sci., Kyushu Univ.)
[1P-926]Intracellular localization analysis of stomatal movement regulation factors PATROL1 and SH3P3 in Arabidopsis under salinity stress
○Mashiro Okamatsu1, Manami Ichita2, Koh Iba3, Takumi Higaki1,2 (1. Faculty of Sci., Kumamoto Univ., 2. Grad. Sch. Sci. Tech., Kumamoto Univ., 3. Kyushu Univ.)
[1P-927]Single cell level root hair RNA-seq to elucidate the mechanism of symbiotic bacterial infection with soybean
○Qianya Su1, Hiroko Matsunaga2,3, Misato Okudaira2, Hidefumi Hamasaki4, Minami Matsui4,5, Haruko Takeyama1,2,3,6 (1. Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2. Res. Org. Nano Life Innov., Waseda Univ., 3. CBBD-OIL, AIST-Waseda Univ., 4. CSRS, RIKEN, 5. Kihara Inst. Biol. Res., Yokohama City Univ., 6. Inst. Adv. Res. Biosyst. Dynam., Waseda Res. Inst. Sci. Eng., Waseda Univ.)
[1P-928]Development of Practical and Rapid Lateral Flow Immunochromatographic Assay Kits for Cucurbit Potyviruses
○Ryo Okada1, Takashi Ogawara2, Shige-Hiro Sugiyama3, Mika Tsuna3, Tomoki Tanaka3, Ayano Sugiyama1 (1. Hort. Res. Inst., Ibaraki AgriCtr, 2. Dept. of Pest Control, Ibaraki AgriCtr, 3. NIPPN CORPORATION Cent. Res. Lab., Food Res. Ctr.)
[1P-929]Simultaneous production of lipids and succinate by metabolic engineering of Euglena gracilis
○Rikuto Oishi1, Ryunosuke Katayama1, Mitsuhiro Ueda1, Tatsuji Sakamoto1, Masami Nakazawa1 (1. Osaka Metropolitan University)
[1P-930]The environment dependent regulation of the expression of MpBONOBO, a key regulator gene for germline differentiation in the liverwort Marchantia polymorpha
○Haruki Okamoto1, Yoshihiro Yoshitake1, Kenta Tanaka1, Tomoaki Kajiwara1, Haonan Bao1, Yukiko Yasui1, Shohei Yamaoka1, Takayuki Kohchi1 (1. Graduate School of Biostudies, Kyoto University)
[1P-931]Comparative Analysis of the Transcriptome of Drought/Salt Stress Resistant and Susceptible Oryza sativa Cultivars: Insights from Public RNA-Sequencing Databases
○Mitsuo Shintani1, Hidemasa Bono1 (1. Grad. Sch. Integ. Sci. Life, Hiroshima Univ.)
[1P-932]Analysis of the effect of homogenization conditions on the formation of supersulfide in onions
○Kirara Tanaka1, Shingo Kasamatsu1, Hideshi Ihara1 (1. Dept. of Biol. Chem., Grad Sch. of Sci., Osaka Met. Univ.)
[1P-933]Can truncation of an autoinhibitory domain of glutamate decarboxylase (GAD) from dicots confer abiotic stress tolerance on the plants?
Nadia Akter1, Ummey Kulsum1, ○Kazuhito Akama1 (1. Grad. School of Nat. Sci., Shimane University)
[1P-934]Analysis of anti-inflammatory effects of compounds isolated from the root of Aralia cordata
○Risa Tanaka1, Asuka Okazaki1, Saki Shirako1, Airi Fujii1, Teruhisa Kawamura1, Yukinobu Ikeya2,3, Mikio Nishizawa1 (1. Ritsumeikan University, 2. Daiichi University Of Pharmacy, 3. Ritsumeikan Research Organization of Science and Technology)
[1P-935]Anti-inflammatory constituents in the root of Atractylodes japonica suppress the induction of adipogenic differentiation in adipocytes
○Yosuke Saito1 (1. Ritsumeikan university)
[1P-936]Ligusticum chuanxiong ethyl acetate extract alleviates hyperuricaemia-related renal injury by regulating uric acid transporters
Rui Zhou1, Kang Ma1, Yan ru Liu1, Jin gao Yu1, Hong bo Liu1, Zhi shu Tang1, ○Hong bo Xu1 (1. Shaanxi University of Chinese Medicine)
[1P-937]Efficient separation of Gastrodia Rhizoma derived Vesicles
based on "regional function" separation and its related application
○Shuming Li1, Hongbo Xu1, Jingyu Weng1, Ke Wang2, Jia Yu1, Yuanyuan Qin1 (1. Shaanxi University of Chinese Medicine, 2. Haojing College of Shaanxi University of Science & Technology)
[1P-938]Molecular mechanisms of heterosis leading to low pH stress tolerance in sugar beet F1 hybrid during early growth.
○Kana Yamada1, Hiroki Ogawa1, Ayumi Kuno1, Masayoshi Suda1, Kotaro Hiroki1, Hiroaki Matsuhira2, Kazuyoshi Kitazaki1 (1. Hokkaido Graduate School of Agriculture, 2. NARO,HARC)
[1P-939]Molecular machineries of plant interspecies barriers explored using calcium imaging
○Chiharu Kato1, Teruaki Goromaru2, Takuya Nagae3, Yoko Mizuta4, Satohiro Okuda1, Akane Mizukami1, Tetsuya Higashiyama1 (1. Graduate School of Science, UTokyo, 2. Graduate School of Science, Nagoya University, 3. Graduate School of Agricultural and Life Sciences, UTokyo, 4. ITbM, Nagoya University)
[1P-940]Role of actin filaments in stomatal closure induced by novel compounds.
○Asuka Kamimura1, Kanane Sato2, Yasuhiro Ishimaru2, Nobuyuki Uozumi2, Takumi Higaki1 (1. Grad. Sch. Sci. & Tech., Univ. Kumamoto, 2. Grad. Sch. Eng.,Univ. Tohoku)
[1P-941]Production of useful proteins in rice under dark conditions with cost effectiveness
Ryota Shimizu1, Akiko Watanabe1, So Shimoda1, Hiroshi Yoneyama1, ○Yukihiro Ito1 (1. Tohoku University)
[1P-942]SLR1, a rice DELLA protein, is fucosylated by a glucosyltransferase SPINDLY in rice
○Hideki Yoshida1, Shunsuke Nishio1, Makoto Matsuoka1 (1. IFeS, Fukushima Univ.)
[1P-943]Identification of genetic mechanisms that produce left-right polymorphism in the Drosophila brain within the population
○Tomoki Yoshida1, So Sakamura2, Wong Wai Cheng1, Kenji Matsuno1 (1. Osaka Univ., 2. University of Hyogo)
[1P-945]Prediction of facial morphology of the Japanese people based on genomic polymorphisms
○Tadashi Imanishi1, Rise Oyachi1 (1. Tokai University School of Medicine)
[1P-946]Monitoring Heatstroke: A Proteomics-Based Multibiomarker Approach to Assess Potential Post-Heatstroke Complications
○Jiayi Jin1, Sing Ying Wong1, Nobuhiro Hayashi1, Toshiaki Iba2 (1. Tokyo Institute of Technology, 2. Juntendo University Graduate School of Medicine)
[1P-947]The study of effects of heatstroke on kidney by proteomics
○Hiroya Kinoshita1, Sing Ying Wong1, Toshiaki Iba2, Nobuhiro Hayashi1 (1. Tokyo Institute of Technology・School of Life Science and Technology, 2. Juntendo University Graduate School of Medicine)
[1P-948]A Novel Stem Cell Therapy for Radiation-induced Intestinal Injury
○Satoshi Kamimura1, Miura Taichi1, Junko Kado1, Hirotoshi Takiyama2, Mitsuko Kawano1, Asako Yamagiri1, Shoko Nishihara3, Shigeru Yamada2, Mayumi Fujita1, Fumiaki Nakayama1 (1. NIRS, QST, 2. QST Hospital, 3. lycan and Life Systems Integration Center (GaLSIC), Soka University)
[1P-949]Mechanisms of Therapeutic Effects of Muse Cells on Radiation-induced Intestinal Injury
○Taichi Miura1, Junko Kado1, Hirotoshi Takiyama2, Mitsuko Kawano1, Asako Yamagiri1, Shoko Nishihara3, Shigeru Yamada2, Satoshi Kamimura1, Mayumi Fujita1, Fumiaki Nakayama1 (1. NIRS, Nat. Inst. for Quantum Sci. and Technol., 2. QST Hospital, 3. Glycan and Life Systems Integration Center (GaLSIC), Soka University)
[1P-950]FoxO3a contributes to skin homeostasis by regulating mitochondrial dynamics
○Kurumi Ogata1, Mariko Moriyama1, Yuko Miyake1, Saki Asada1, Saya Goto1, Hiroyuki Moriyama1 (1. Pharm. Res. Technol. Instit., Kindai Univ.)
[1P-951]FoxO3a Promotes Scarless Wound Healing
○Saki Asada1, Mariko Moriyama1, Yuko Miyake1, Kurumi Ogata1, Saya Goto1, Hiroyuki Moriyama1 (1. Pharm Res Technol Inst., Kindai Univ.)
[1P-952(1AS-07-04)]Exploring Parkinson’s disease related genes using unknomics and transcriptomics
○Suzuki Takayuki1, Bono Hidemasa1 (1. Hiroshima University)
[1P-953]Muscle contractile activity-induced NBR1 and phosphorylated p62/SQSTM1 contribute to regulating antioxidant protein expression in muscle
○Hinata Ito1, Mami Yamada1, Masahiro Iwata2, Mitsuharu Okutsu1 (1. Nagoya City University, 2. Nihon Fukushi University)
[1P-954]Inhibition of L-type amino acid transporter 1 alleviates testosterone-induced benign prostatic hyperplasia both in vitro and in vivo
○Kyunghyun Kim1, Hui-Ju Lee1, Yae-Ji Kim1, Sung-Pil Cho1, Geum-Lan Hong1, Ju-Young Jung1 (1. Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University)
[1P-955]Development of Novel Antibody Therapeutics for Inflammatory Skin Diseases
○Rie Kinoshita1, Yuma Gohara1, Nahoko Tomonobu1, Ken-ichi Yamamoto1, Hitoshi Murata1, Tomoko Honjo2, Junichiro Futami2, Kazumi Sagayama3, Masakiyo Sakaguchi1 (1. Okayama Univ., Grad. Sch. Med. Dent. Pharm. Sci., 2. Okayama Univ., Grad. Sch., Dept. Interdisciplinary Sci., 3. Okayama Univ., Organization for Research and Innovation Strategy)
[1P-956]Effects of molecular hydrogen on acute liver injury in a diabetic mouse model
○Naomi Kamimura1, Katsuya Iuchi2, Tsutomu Igarashi3, Ikuroh Ohsawa4, Chikako Nito1, Masahiro Seike1, Shigeo Ohta5 (1. Lab. Clin. Res., Collab. Res. Ctr., Nippon Med. Sch., 2. Dept. Mol. Diag. Cancer Prev., SCC, 3. Dept. Ophthalmology, Nippon Med. Sch.Dept., 4. Biol. Process Aging, TMIG, 5. Dept. Neurol. Med., Grad. Med. Sch., Juntendo Univ.)
[1P-957]Modulation of Asthma by RET Inhibition Targeting PNEC Hyperplasia and Airway Inflammation.
○Erina Ike1, KAWANO TASUKU1, TAKAHASHI KENTO1, TAKAHASHI TOMOKO1 (1. Div. Pathophysiology, Fac. Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University)
[1P-958(1PS-05-05)]Comprehensive single-cell analysis of stromal cells in liver fibrosis resolution
○Eiko Saijou1, Luis AE Nagai1, Tohru Itoh2, Naoko Yokota1, Ryuichiro Nakato1 (1. Computational Genomics, IQB, Univ. Tokyo, 2. Research Core, Institute of Research, TMDU)
[1P-959]Investigating the Feasibility of Gene Delivery via the Intraplacental Route of Delivery
○Natalia Gogoleva1,2, Michito Hamada1,3, Satoru Takahashi1,3 (1. Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 2. Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 3. Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba)
[1P-960]Evaluation of ecNGS method for in vivo mutagenicity detection using rat samples
○Kazuki Izawa1, Masataka Tsuda1, Takayoshi Suzuki1, Masamitsu Honma2, Kei-ichi Sugiyama1 (1. NIHS, Division of Genome Safety Science, 2. NIHS, Division of General Affairs)
[1P-961]Proteomics for the relationship between menstruation and subjective condition
○Kai Fushimi1, Tasuku Kondo1, Nodoa Ikegami2, Mizuki Yamada2, Sing Ying Wong 1, Mikako Sunaga2, Nobuhiro Hayashi1 (1. Tokyo Institute of Technology, School of Life Science and Technology, 2. NSSU)
[1P-962]Spatial sampling and culture of cells using blade array devices
○Kumiko Isehama1, Daichi Hirai2, Takumi Ito2, Kyohei Terao1 (1. Faculty of Engineering and Design, Kagawa University, 2. Graduate School of Science for Creative Emergence, Kagawa University)
[1P-963]Genetic dissection of the core mechanisms and physiological triggers of cell competition
○Ryo Matsumoto1, Hiroshi Kanda1, Aya Kawasaki1, Mai Nakamura1, Rina Nagata1, Xinyue Huang1, Ayumu Okumura1, Naotaka Ochi1, Naoki Wakasa1, Yoji Noguchi1, Ryosuke Nakano1, Shu Kondo4, Keta Miyoshi2,3, Tomoe Kobayashi5, Makoto Matsuyama5, Kuniaki Saito2,3, Tatsushi Igaki1 (1. Lab of Genetics, Graduate School of Biostudies, Kyoto Univ., 2. Dept. of Chromosome Science, National Institute of Genetics, 3. Graduate Institute for Advanced Studies, SOKENDAI, 4. Dept. of Biological Science and Technology, Tokyo Univ. of Science, 5. Division of Molecular Genetics, Shigei Medical Research Institute)
[1P-964]Study on the regulatory mechanisms of the Igf-Mapk pathway in catch-up growth induced by fluctuated environmental temperature in zebrafish embryos
○Yuto Nakagawa1, Oki Hayasaka1, Souma Miyano1, Hiroyasu Kamei1 (1. Kanazawa Univ.)
[1P-965(1PS-02-03)]Spatial transcriptome analysis in tardigrades using Stereo-Seq
○Sae Tanaka1,2, Kazuharu Arakawa1,2 (1. ExCELLS, NINS, 2. IAB, Keio Univ)
[1P-966]Additive antitumor effect of arsenic trioxide with exposure to ionizing radiation to human acute promyelocytic leukemia HL60 cells
○Satoru Monzen1,2, Yuki Morino1, Hikoto Sugiyama1, Kazuma Yamane1, Megumi Kikuchi1, Mitsuru Chiba3, Takamasa Yamanaka1, Yoichiro Hosokawa1 (1. Dep. of Rad. Sci., Hirosaki Univ., 2. RCBS., Hirosaki Univ., 3. Dep. of Lab. Sci., Hirosaki Univ.)
[1P-967]Effective Utilization of Caenorhabditis elegans as a Powerful Biosensor for Cancer Detection
○Masayo Morishita1, Hideyuki Hatakeyama1, Takaaki Hirotsu1, Eric di Luccio1 (1. HIROTSU BIO SCIENCE Inc.)
[1P-968]Research of the functionality of citrus-derived limonoids under heat stress
○Takuma Hashimoto1, Takumi Iwasawa1, Kazunori Kato1 (1. Dept. Nutrition Sci., Grad. Sch. Health and Sports Sci. Toyo Univ.)
[1P-969]The N-Nose: A Non-Invasive Biosensor Revolutionizing Cervical Cancer Screening in Underserved Populations
○Aya Hasan Alshammari1, Takaaki Hirotsu1, Hideyuki Hatakeyama1, Eric di Luccio1 (1. HIROTSU BIO SCIENCE INC.)
[1P-970]DNA damage accumulation impedes cardiac repair after myocardial infarction by diminishing IL-10 expression
○Chiemi Sakai1, Mari Ishida1, Yusuke Kobayashi1, Satoshi Tashiro2, Takafumi Ishida3 (1. Hiroshima Univ., 2. Hiroshima Univ. Res. Inst. Rad. Biol. and Med., 3. Fukushima Med. Univ.)
[1P-971]Strain-dependent differential expression of silk-related genes in silk glands induced by dietary differences in Bombyx mori
○Tsuneyuki Tatsuke1, Shuichiro Tomita1 (1. National Agriculture and Food Research Organization)
[1P-972]Regulation of glutathione S-transferase A isoforms by testosterone in mouse kidneys
○Doug-Young Ryu1, Herin Hwang1, Youngseo Park1 (1. Seoul National University)
[1P-973]Teaching an Old Bacterium New Tricks: Evolving Novel Predictive Behaviors in E. Coli
○Juan Moreno Nadales1, Hiroki Kojima2, Liam Longo1,3 (1. Tokyo Institute of Technology, 2. University of Tokyo, 3. Blue Marble Space Institute of Science)