The 47th Annual Meeting of the Molecular Biology Society of Japan
Advanced Search

Session Details

Open-call Symposium : [1AS-11] Next generation multi-omics life science for understanding DNA life cycle

[1AS-11]【J】Next generation multi-omics life science for understanding DNA life cycle

Wed. Nov 27, 2024 9:00 AM - 11:15 AM JST
Wed. Nov 27, 2024 12:00 AM - 2:15 AM UTC
Room 11(Fukuoka International Congress Center, 2F 202)
Organizer: Seitaro Nomura (The University of Tokyo), Hiroyuki Aburatani (The University of Tokyo)
Throughout life, living organisms use the genomic DNA within their cells to carry out genetic programs. Genomic DNA is constantly exposed to various internal and external stresses and is damaged, which is repaired to maintain cell function. However, excessive DNA damage not only causes cell death, but even after the damage is repaired, it induces cellular senescence and genomic mutations leading to cancer. This symposium will focus on DNA damage, which is a common molecular mechanism in organismal development and disease, and introduce research that makes full use of cutting-edge next-generation technologies such as long-read sequencing, next-generation sequencing, single-cell analysis, spatial analysis, innovative imaging technology, and genome editing. Based on these studies, we would like to deepen our understanding of the DNA life cycle in biological phenomena and discuss its significance.
9:00 AM - 9:15 AM JST(12:00 AM - 12:15 AM UTC)

[1AS-11-01]Understanding DNA life cycle in cardiovascular disease through new multi-omics life sciences

○Seitaro Nomura1 (1. The University of Tokyo)
Comment()
9:15 AM - 9:35 AM JST(12:15 AM - 12:35 AM UTC)

[1AS-11-02]Understanding early carcinogenesis through multiomics analysis of single cell-derived samples

○Kenichi Yoshida1 (1. National Cancer Center)
Comment()
9:35 AM - 9:45 AM JST(12:35 AM - 12:45 AM UTC)

[1AS-11-03(1P-074)]Visualization of the native nucleosome containing the histone variant H2A.X

○Haotong Zhuang1,2, Suguru Hatazawa1, Cheng-han Ho1, Yoshimasa Takizawa1,2, Hitoshi Kurumizaka1 (1. Institute for Quantitative Biosciences, The University of Tokyo, Japan, 2. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Japan)
Comment()
9:45 AM - 10:05 AM JST(12:45 AM - 1:05 AM UTC)

[1AS-11-04]Understanding aged cells through omics analysis

○Hiroyuki Matsumura1 (1. Endowed Chair in CelI Aging Control, Graduate School of Science, The University of Tokyo)
Comment()
10:05 AM - 10:15 AM JST(1:05 AM - 1:15 AM UTC)

[1AS-11-05(1P-028)]Shin-RamDA-seq: A high-sensitivity approach for single-cell transcriptomic analysis and precise detection of genomic structural variants

○Tetsutaro Hayashi1, Mariko Kuse1, Haruka Ozaki2, Mika Yoshimura1, Tempei Sato1, Kenzui Taniue3, Nobuyoshi Akimitsu3, Itoshi Nikaido1 (1. RIKEN, 2. Univ. of Tsukuba, 3. Univ. of Tokyo)
Comment()
10:15 AM - 10:35 AM JST(1:15 AM - 1:35 AM UTC)

[1AS-11-06]Comprehensive profiling of genomic structural variants and aberrant cytosine methylation of cancer genome using long-read sequencing

○Genta Nagae1, Yu-an Chen1, Kenji Tatsuno1, Hiroki Ueda2, Hiroyuki Aburatani1 (1. Gen Sci & Med, RCAST, the University of Tokyo, 2. Adv Data Sci, RCAST, the University of Tokyo)
Comment()
10:35 AM - 10:45 AM JST(1:35 AM - 1:45 AM UTC)

[1AS-11-07(1P-072)]Regulation of γH2AX domain expansion in DNA damage response

○Kyoichi Isono1, Ryo Onishi2, Yaoi Kimura3, Junichiro Takano2, Koyama Momo1, Haruhiko Koseki2 (1. Wakayama Med Univ, 2. RIKEN IMS, 3. Yokohama City Univ)
Comment()
10:45 AM - 11:05 AM JST(1:45 AM - 2:05 AM UTC)

[1AS-11-08]Elucidation of cancer etiology and mechanisms based on DNA adduct analysis

○Yukari Totsuka1 (1. Hoshi University)
Comment()
11:05 AM - 11:15 AM JST(2:05 AM - 2:15 AM UTC)

[1AS-11-09]Epigenetic plasticity in human cancer tissue

○Hiroyuki Aburatani1 (1. The University of Tokyo)
Comment()
Back to Category List