The 47th Annual Meeting of the Molecular Biology Society of Japan
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Open-call Symposium : [1PS-01] Understanding aging and cancer based on abnormalities in “shape"

[1PS-01]【J】Understanding aging and cancer based on abnormalities in “shape"

Wed. Nov 27, 2024 4:45 PM - 7:00 PM JST
Wed. Nov 27, 2024 7:45 AM - 10:00 AM UTC
Room 1(Fukuoka International Congress Center, 5F 501)
Organizer: Keiko Kawauchi (Konan University), Midori Shimada (Nagoya University)
Longevity and maintaining good health while aging are some major desires of humankind. Elucidation of the molecular mechanisms of aging and cancer is key to achieve the goal. Numerous studies have been carried out from the molecular and cellular levels to whole-body level. In this symposium, we will share insights from research in various fields, such as biology, chemistry, and computational science, regarding "the abnormal shapes" observed in aging and cancer and treatments targeting the abnormality.
4:45 PM - 4:48 PM JST(7:45 AM - 7:48 AM UTC)

Introduction

4:48 PM - 5:08 PM JST(7:48 AM - 8:08 AM UTC)

[1PS-01-01]Multi-omics regulation of NFκB in cellular senescence

Shou Soeda1, Keita Matsuda1, ○Mariko Okada1 (1. IPR, Osaka University)
Comment()
5:08 PM - 5:18 PM JST(8:08 AM - 8:18 AM UTC)

[1PS-01-02(1P-820)]Spatial transcriptome reveals the mechanisms underlying competitive communication between oncogenic cells and neighbors.

○Mai Miyake1, Yuki Akieda1, Yukinari Haraoka1, Kaori Tanaka2, Akihito Harada2, Yasuyuki Ohkawa2, Tohru Ishitani1 (1. Dept. of Homeostatic Regulation, RIMD, Osaka Univ., 2. Dept. of Transcriptomics, MiB, Kyushu Univ.)
Comment()
5:18 PM - 5:30 PM JST(8:18 AM - 8:30 AM UTC)

[1PS-01-03(1P-793)]Mitochondrial structural changes in response to nuclear DNA damage triggers cellular senescence

○Shota Yamauchi1, Hidenori Ichijo2, Akiko Takahashi1 (1. JFCR, 2. Tokyo Med. Dent. Univ.)
Comment()
5:30 PM - 5:42 PM JST(8:30 AM - 8:42 AM UTC)

[1PS-01-04]The role of calcium signaling in cancer cell proliferation

○Makoto Habara1, Yuki Sato2, Shunsuke Hanaki1, Takahiro Masaki1, Haruki Tomiyasu1, Yosei Miki1, Midori Shimada2 (1. Yamaguchi Univ., 2. Nagoya Univ.)
Comment()
5:42 PM - 6:02 PM JST(8:42 AM - 9:02 AM UTC)

[1PS-01-05]Mechanisms of age-related cancer progression

○Makoto Nakanishi1 (1. The Institute of Medical Science, The University of Tokyo)
Comment()
6:02 PM - 6:17 PM JST(9:02 AM - 9:17 AM UTC)

[1PS-01-06]Liquid-liquid phase separation induced by non-canonical structures of nucleic acids

○Daisuke Miyoshi1, Mitsuki Tsuruta1, Yoshiki Hashimoto1, Shumit Shil1, Keiko Kawauchi1 (1. Konan University)
Comment()
6:17 PM - 6:27 PM JST(9:17 AM - 9:27 AM UTC)

[1PS-01-07]Loss of p53 function alters nucleolar dynamics induced by anti-tumor drugs

○Keiko Kawauchi1, Takeru Torii1, Shinya Taniguchi1, Hiroaki Hirata2, Miwako Kato Homma3, Daisuke Miyoshi1 (1. Konan Univ. FIRST, 2. Kanazawa Inst. Tech., 3. Fukushima Med. Univ. Sch. Med.)
Comment()
6:27 PM - 6:37 PM JST(9:27 AM - 9:37 AM UTC)

[1PS-01-08]Hydrostatic pressure induces nuclear softening of pancreatic cancer cells via regulation of Histone H3 methylation and Lamin A/C localization.

Norino Uenaka1, ○Daisuke Yoshino1 (1. TUAT)
Comment()
6:37 PM - 6:57 PM JST(9:37 AM - 9:57 AM UTC)

[1PS-01-09]Understanding the whole picture of cancer metabolism: Towards establishing treatments for malignant cancers

○Keiichih Nakayama1 (1. Lab. Anticancer Strategies, Advanced Res. Inst., Inst. Sci. Tokyo)
Comment()
6:57 PM - 7:00 PM JST(9:57 AM - 10:00 AM UTC)

Conclusion

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