Session Details
[1MS-07]【J】Reprometabolism: Nutritional and metabolic control of the reproductive cycle
Wed. Nov 27, 2024 3:10 PM - 4:30 PM JST
Wed. Nov 27, 2024 6:10 AM - 7:30 AM UTC
Wed. Nov 27, 2024 6:10 AM - 7:30 AM UTC
Room 7(Fukuoka International Congress Center, 4F 413)
Organizer: Yohei Hayashi (Tohoku University), So Maezawa (Tokyo University of Science)
Germline emerges as primordial germ cells during embryogenesis and is maintained for a long period of time to maintain the reproductive function. The nutritional condition derived from mother during embryogenesis and neonatal development, and from the surrounding environment during adulthood, influences the metabolic state of germ cells and supporting cells, and is Involved in the control of epigenomic state and reproductive function. However, the research to elucidate such mechanisms is only just beginning. In this project, we will discuss the progress and perspectives of this field of research, which we define as "Reprometabolism".
Introduction
[1MS-07-01]Folic acid deficiency alters germline epigenome during mouse spermatogenesis
Ai Ikuyo1, Kai Otsuka1, Nozomu Fuse1, Mizuho Iizuka1, Hayashi Yohei2, Tomoyoshi Soga3, ○So Maezawa1 (1. Dept. of Appl. Biol. Sci., Tokyo Univ. of Sci., 2. IDAC, Tohoku Univ., 3. SFC, Keio Univ.)
[1MS-07-02]Role of iron in mouse sex determination
○Naoki Okashita1, Makoto Tachibana1 (1. Osaka University)
[1MS-07-03]Regulation of gonadal supporting cells by phosphoinositides and its effect on reproduction
○Junko Sasaki1, Shogo Yanai1, Hiroaki Kajiho1, Takehiko Sasaki1 (1. Medical Research Institute, TMDU)
[1MS-07-04]Functional analysis of the SGOC pathway in epigenomic regulation of mouse 1-cell stage embryos
○Masatoshi Ooga1 (1. Azabu University)
[1MS-07-05]Diabetes-induced Abnormalities in sperm epigenome and their inheritance to the next generation.
Beverly Boyboy1, Yamato Ohtsuka1, Tomoko Ichiyanagi1, Hirohisa Nitta1, ○Kenji Ichiyanagi1 (1. Nagoya Uni.)
[1MS-07-06]DNA methylation alterations in F1 sperm by gestational arsenic exposure of F0 mice and their inheritance in both parent genomes of F2 embryos after epigenetic reprogramming
○Keiko Nohara1, Takehiro Suzuki1, Kazuyuki Okamura1, Kazuhiko Nakabayashi2 (1. National Institute for Environmental Studies, 2. National Center for Child Health and Development)