Session Details

[2PS-10]【E】Synergistic Advancement of new technologies with mitochondrial research

Thu. Nov 28, 2024 4:45 PM - 7:00 PM JST
Thu. Nov 28, 2024 7:45 AM - 10:00 AM UTC
Room 10(Fukuoka International Congress Center, 2F 201)
Organizer: Keisuke Takeda (Osaka University), Masafumi Noguchi (Wakayama Medical University)
Mitochondria integrate cellular signaling and metabolism, thereby determining the fate of organisms. Here, we introduce innovative technologies that unveil previously hidden aspects of mitochondrial biology and pathophysiology, which were obscured by past methodological limitations. The use of newly innovated and developed technologies, such as gene-editing technology, deep-learning, and regenerative engineering, would enable us to overcome the limitations of scientific approaches.

Introduction

[2PS-10-01]The Impact of Mitochondrial Inner Membrane Factor OPA1 on Airway Stem Cell Maintenance

○Masafumi Noguchi1, Sakuya Yamamoto1, Keiko Iwata1, Norihito Shintani1,2, Luca Scorrano3,4 (1. Lab. Pharmacology, Sch. Pharm. Sci., Wakayama Med. Univ., 2. Lab. Mol. Neuropharmacol., Grad. Sch. Pharm. Sci., Osaka Univ., 3. Dept. Biol., Univ. Padova, 4. Venet. Inst. Mol. Med.)
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[2PS-10-02]Targeted A-to-G base editing in the organellar genomes of Arabidopsis with monomeric programmable deaminases

○CHANG ZHOU1, Mirai Okuno2, Issei Nakazato1,3, Nobuhiro Tsutsumi1, Shin-ichi Arimura1 (1. Tokyo Univ., 2. Kurume Univ., 3. Japan Society for the Promotion of Science)
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[2PS-10-03]Treatment of diabetic complications focusing on the maintenance of mitochondrial quality

○Yuri Kato1, Motohiro Nishida1,2 (1. Kyushu Univ., 2. NIPS)
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[2PS-10-04]Elucidating the in vivo Mitochondrial Ultrastructure in Retinal Ganglion Cells Using Deep Learning-Based Analysis

○Shogo Suga1, Yu Nakanishi1, Hajime Komaki1, Nobuhiko Ohno2,3, Hiroki Kawai1, Yusuke Hirabayashi1 (1. School of Engineering, The University of Tokyo, 2. Department of Anatomy, Division of Histology and Cell Biology, School of Medicine, Jichi Medical University, 3. Division of Ultrastructural Research, National Institute for Physiological Sciences)
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[2PS-10-05]Pharmacologically increasing Opa1 expression levels by silencing the miR-148/152 family improves the phenotype in mitochondrial myopathy.

○Andre Djalalvandi1,2, Francesca Grespi1,2, Keisuke Takeda1,2, Tiago Fonseca1,2, Hualin Fan1,2, Carlotta Barison1,2, Davide Steffan1,2, Camilla Bean1,2, Martina Semenzato1,2, Akiko Omori1,2,Luca Scorrano1,2 (1. University of Padua, 2. Venetian Institute of Molecular Medicine)
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[2PS-10-06]Development and Utilization of Mitophagy Reporter Mice

○Keiichi Inoue1,2, Shun-ichi Yamashita1,2, Tomotake Kanki1,2 (1. Kyushu University, 2. Niigata University)
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Conclusion