The 47th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Open-call Symposium : [2PS-06] Epigenetic regulation from development to disease and its therapeutic application

[2PS-06]【J】Epigenetic regulation from development to disease and its therapeutic application

Thu. Nov 28, 2024 4:45 PM - 7:00 PM JST
Thu. Nov 28, 2024 7:45 AM - 10:00 AM UTC
Room 6(Fukuoka International Congress Center, 4F 411+412)
Organizer: Hideyuki Takeshima (Hoshi University), Hisanori Takenobu (Saitama Cancer Center)
Epigenome is essential for the development of our bodies. However, epigenome can be altered by various environmental stimuli, and the accumulation of these alterations can lead to the development of various diseases, such as cancers. In this symposium, we will focus on the epigenome and its regulators, and introduce the molecular mechanisms by which their dysregulation induces the diseases. We will also discuss the recent advancement of therapeutic strategies targeting epigenome dysregulations.
4:45 PM - 4:48 PM JST(7:45 AM - 7:48 AM UTC)

Introduction

4:48 PM - 5:03 PM JST(7:48 AM - 8:03 AM UTC)

[2PS-06-01]Targeting methylation-silenced genes as a rich source of synthetic lethality

○Hideyuki Takeshima1, Takahiro Ebata1, Yui Ohashi1, Yumi Furuichi1, Toshikazu Ushijima1 (1. Hoshi University)
Comment()
5:03 PM - 5:16 PM JST(8:03 AM - 8:16 AM UTC)

[2PS-06-02(2P-107)]Epigenomic Regulation of Enhancer Regions Characterizing Breast Cancer

○Hiroaki Tachiwana1, Noriko Saitoh1 (1. The Cancer Institute of JFCR)
Comment()
5:16 PM - 5:29 PM JST(8:16 AM - 8:29 AM UTC)

[2PS-06-03(2P-110)]How p300/CBP propagates epigenomic acetylation

○Takashi Umehara1 (1. RIKEN)
Comment()
5:29 PM - 5:44 PM JST(8:29 AM - 8:44 AM UTC)

[2PS-06-04]Natural Products Affecting Epigenomic States of Cells

○Yoichi Nakao1 (1. Waseda University)
Comment()
5:44 PM - 5:59 PM JST(8:44 AM - 8:59 AM UTC)

[2PS-06-05]Elucidating the Mechanism of Meiotic Initiation through MAX in Germ Cells

○Ayumu Suzuki1, Kousuke Uranishi1, Nishimoto Masazumi1, Mizuno Yousuke2, Mizuno yousuke3, Satoru Takahashi4, Akihiko Okuda1 (1. Div. Biomed. Sci., Saitama Med. Univ., 2. Morphol. Sci., Biomed. Res. Center, Saitama Med. Univ., 3. Dept. of Anim sci., Univ. of Tsukuba, 4. AnaEmb, Med. Univ. of Tsukuba)
Comment()
5:59 PM - 6:14 PM JST(8:59 AM - 9:14 AM UTC)

[2PS-06-06(2P-103)]Unraveling the Potential Chromatin Regulatory Mechanisms of Polycomb Complexes (PcG) on Future Gene Expression Patterns.

○Mio Harachi1, Shinsuke Ito1, Takashi Kondo1, Nayuta Yakushiji1, Ryo Onishi1, Haruhiko Koseki1 (1. RIKEN IMS Genes&Dev)
Comment()
6:14 PM - 6:29 PM JST(9:14 AM - 9:29 AM UTC)

[2PS-06-07]CDX1 regulates stemness and proliferation thru gene expression in neuroblastoma cells

○Hisanori Takenobu1, Ryuichi P Sugino1, Miki Ohira1, Masayuki Haruta1, Nobuhiro Akita2,3, Osamu Shimozato2, Shunpei Satoh1, Kyosuke Mukae1, Tomoko Wada1, Takehiko Kamijo1,4 (1. Research Institute for Clinical Oncology, Saitama Cancer Center, 2. Research Institute, Chiba Cancer Center, 3. Japanese Red Cross Aichi Medical Center, 4. Department of Graduate School of Science and Engineering, Saitama University)
Comment()
6:29 PM - 6:42 PM JST(9:29 AM - 9:42 AM UTC)

[2PS-06-08(2P-098)]A functional analysis of lysine-specific demethylase KDM7A in pro-fibrotic macrophage overpolarization.

○Naofumi Funagura1,2, Tomoaki Koga1, Seonghyeon Hong1, Kan Etoh1, Ayane Noda1, Toshihiro Inoue2, Mitsuyoshi Nakao1 (1. IMEG Kumamoto Univ., 2. Kumamoto Univ.)
Comment()
6:42 PM - 6:57 PM JST(9:42 AM - 9:57 AM UTC)

[2PS-06-09]Epigenetic heterogeneity in cancer-associated fibroblast of pancreatic cancer

○Keiko Shinjo1, Xingxing Wang1, Kohei Kumegawa2, Reo Maruyama2, Shinji Mii1, Yoshiteru Murofushi1, Miho Suzuki1, Atsushi Enomoto1, Yutaka Kondo1 (1. NAGOYA UNIVERSITY, 2. Japanese Foundation for Cancer Research)
Comment()
6:57 PM - 7:00 PM JST(9:57 AM - 10:00 AM UTC)

Conclusion

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