Session Details
[3PS-01]【E】Manifestation of junk DNA functionality through noncoding RNA expression and its inhibition mechanisms
Fri. Nov 29, 2024 4:45 PM - 7:00 PM JST
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Room 1(Fukuoka International Congress Center, 5F 501)
Organizer: Tetsuro Hirose (Osaka University), Misuzu Kurihara (Hokkaido University)
Recently, various noncoding RNAs have been recognized to be synthesized from dispersed junk repeat regions in the genome, suggesting their potential for playing crucial regulatory roles. Concurrently, these repeat regions can induce genomic mutations as mobile elements and disrupt gene expression. Cells have developed sophisticated RNA-based inhibitory mechanisms to suppress the harmful effects of these regions. This symposium focuses on the intricate mechanisms involved in the tug-of-war related to junk regions in the genome, examining the production of noncoding RNAs as a driving force for the functional expansion of genomes.
Introduction
[3PS-01-01]RNA aggregation in neurodegenerative disease
○Ankur Jain1 (1. Whitehead Institute/MIT)
[3PS-01-02]Multifaceted functions of HSATIII repeat RNAs in stress response
○Kensuke Ninomiya1, Shungo Adachi2, Tetsuro Hirose1,3 (1. FBS, Osaka Univ., 2. NCCRI, 3. OTRI, Osaka Univ.)
[3PS-01-03(3P-209)]How centromeric RNA regulates chromosomal segregation
○Saho Matsui1,2, Ryusuke Nozawa1, Anna Suzuki1,2, Toru Hirota1,2 (1. Div. Exp. Pathol. Cancer Inst. JFCR, 2. Dept. JFCR., Tokyo Med. & Dent. Univ.)
[3PS-01-04]RNA polymerase II-mediated rDNA transcription is necessary for rDNA copy number expansion in Drosophila
○George J Watase1 (1. IMEG, Kumamoto University)
[3PS-01-05]RNA processing across evolution
○Tugce Aktas1 (1. Max Planck Institute for Molecular Genetics)
[3PS-01-06(3P-611)]The Role of Refee in Proper Stage-Specific Expression and Functionality of Mouse Endogenous Retrovirus L
○Mie Kobayashi-Ishihara1, Akihiko Sakashita1, Hirotsugu Ishizu1, Youjia Guo1, Tomohiro Kitano1, Masaru Ariura1, Hidetoshi Hasuwa1, Kensaku Murano1, Hidetaka Kosako2, Haruhiko Siomi1 (1. Keio University School of Medicine, 2. Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University)
[3PS-01-07]Autonomous Shaping of the piRNA Sequence Repertoire by Competition between Adjacent Ping-Pong Sites
Jie Yu1, Natsuko Izumi1, ○Yukihide Tomari1,2, Keisuke Shoji1,3 (1. IQB, UTokyo, 2. GSFS, UTokyo, 3. BASE, TUAT)
[3PS-01-08]Regulation of chromosome stability by large tandem repeat cluster
○Misuzu Kurihara1, Ryouta Kawano1 (1. Hokkaido University)