The 47th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Open-call Symposium : [3PS-14] Frontiers of Disease Molecular Biology Unraveling “Life-Aging-Disease-Death"

[3PS-14]【J】Frontiers of Disease Molecular Biology Unraveling “Life-Aging-Disease-Death"

Fri. Nov 29, 2024 4:45 PM - 7:00 PM JST
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Room 14(Marine Messe Fukuoka Hall B, 2F Meeting Room 1-1)
Organizer: Tomoaki Tanaka (Chiba University), Tohru Minamino (Juntendo University)
Multi-faceted networks of aging signals and metabolic stresses are involved in diverse disease molecular pathophysiology, confounding cellular aging as well as organ and individual aging. The development of organ-to-cell/cell interaction analysis and data science using single cell and spatial transcriptomics analysis, coupled with the progress of highly sensitive proteomics and multi-omics analysis, has made it possible to understand underlying mechanisms and regulatory systems from multiple perspectives.In this symposium, under the theme of "Disease Molecular Biology Unraveling Life-Aging-Disease-Death," we will introduce pioneering research that has opened up new perspectives. We hope to deepen our discussion on future developments and possibilities.
4:45 PM - 4:46 PM JST(7:45 AM - 7:46 AM UTC)

Introduction

4:46 PM - 5:04 PM JST(7:46 AM - 8:04 AM UTC)

[3PS-14-01]The LSD1 inhibitor, TAS1440 suppresses neuroendocrine small cell lung cancer growth by activating TGF-β and NOTCH signaling via LSD1-INSM1 complex disruption

○Tomoaki Tanaka1, Shuichi Ohkubo2 (1. Chiba University Graduate School of Medicine , 2. Taiho Pharmaceutical Co., Ltd.)
Comment()
5:04 PM - 5:17 PM JST(8:04 AM - 8:17 AM UTC)

[3PS-14-02(3P-792)]Understanding skeletal muscle aging mechanisms through changes of dorsoventral patterns with aging

○Hikaru Ino1, Kota Abe1, Tohru Ishitani1 (1. Department of Homeostatic Regulation, Division of Cellular and Molecular Biology. Research Institute for Microbial Diseases, Osaka University)
Comment()
5:17 PM - 5:35 PM JST(8:17 AM - 8:35 AM UTC)

[3PS-14-03]Cytoplasmic DNA and Neurodegeneration

○Hideaki Matsui1 (1. Niigata University)
Comment()
5:35 PM - 5:53 PM JST(8:35 AM - 8:53 AM UTC)

[3PS-14-04]Development of in vivo labeling tools to elucidate the dynamics of inflammatory cells in Alzheimer’s disease

○Kenichi Nagata1,2, Kazuto Yoshimi3, Shoko Hashimoto4, Daisuke Motooka5, Takaomi C. Saido2, Hiroki Sasaguri2, Hiroshi Kiyama1,6 (1. Nagoya University Graduate School of Medicine, 2. RIKEN Center for Brain Science, 3. Institute of Medical Science, University of Tokyo, 4. Medical Innovation Research Center, Shiga University of Medical Science, 5. Research Institute for Microbial Diseases, Osaka University, 6. Shijonawate Gakuen University)
Comment()
5:53 PM - 6:06 PM JST(8:53 AM - 9:06 AM UTC)

[3PS-14-05(3P-721)]Sustaining microglial reparative function enhances stroke recovery

○Jun Tsuyama Tsuyama1, Ayaka Nakamura1,2, Takashi Shichita1 (1. Tokyo Medical and Dental University, 2. Keio University)
Comment()
6:06 PM - 6:24 PM JST(9:06 AM - 9:24 AM UTC)

[3PS-14-06]Kidney DNA damage and systemic aging

○kaori Hayashi1 (1. Keio University School of Medicine)
Comment()
6:24 PM - 6:42 PM JST(9:24 AM - 9:42 AM UTC)

[3PS-14-07]Aging alteration of human skin resident memory T cells

○Rei Watanabe1 (1. Juntendo University)
Comment()
6:42 PM - 6:59 PM JST(9:42 AM - 9:59 AM UTC)

[3PS-14-08]Targeting seno-anergy for the treatment of age-associated disease

○TOHRU MINAMINO1 (1. Department of Cardiovascular Biology and Medicine Juntendo University Graduate School of Medicine)
Comment()
6:59 PM - 7:00 PM JST(9:59 AM - 10:00 AM UTC)

Conclusion

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