Session Details

[3PS-02]【J】Recent Developments in Research Using Pluripotent Stem Cells

Fri. Nov 29, 2024 4:45 PM - 7:00 PM JST
Fri. Nov 29, 2024 7:45 AM - 10:00 AM UTC
Room 2(Fukuoka International Congress Center, 5F 502+503)
Organizer: Yohei Hayashi (RIKEN), Yuichiro Miyaoka (Tokyo Metropolitan Institute of Medical Science)
Human pluripotent stem cells are widely used as versatile and valuable tools and resources, contributing to regenerative medicine and drug discovery as part of molecular, cellular, and developmental biology and its applied research and development for human biological phenomena for which in vivo experiments cannot be performed. This symposium will introduce advanced studies using human pluripotent stem cells in the areas of reprogramming, genome editing, pioneering factors, transcriptome, proteome, disease modeling, and therapeutic development, and will provide an opportunity to consider the future use and further development of pluripotent stem cells.

Introduction

[3PS-02-01]Use of iPS cells as bioresources

○Yohei Hayashi1 (1. RIKEN)
Comment()

[3PS-02-02(3P-543)]Recapitulation of first pharyngeal arch-specific regional patterning and generation of oral organs using human induced pluripotent stem cells

○Souta Motoike1, Yoshiko Inada1, Junya Toguchida2, Mikihito Kajiya3, Makoto Ikeya1 (1. Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 2. Department of Fundamental Cell Technology, Center for iPS Cell Research and Application, Kyoto University, 3. Department of Innovation and Precision Dentistry, Hiroshima University Hospital)
Comment()

[3PS-02-03(3P-534)]Generation of skin graft in vivo by cell competition.

○Hisato Nagano1, Naoaki Mizuno1,2, Hideyuki Sato1, Eiji Mizutani3, Ayaka Yanagida4, Mayuko Kano5, Mariko Kasai1, Hiromi Yamamoto1, Motoo Watanabe1, Suchy Fabian6, Hideki Masaki1, Hiromitsu Nakauchi1,6 (1. Tokyo Medical and Dental University, Stem Cell Therapy Laboratory, 2. Tokyo Medical and Dental University, Center for Experimental Animals, Department of Experimental Animal Model for Human Disease, 3. University of Tsukuba, Laboratory of Stem Cell Therapy, 4. The University of Tokyo, Department of Veterinary Anatomy, 5. St. Marianna University School of Medicine, Metabolism and Endocrinology, Department of Medicine, 6. Stanford University, Institute for Stem Cell Biology and Regenerative Medicine)
Comment()

[3PS-02-04]Novel Pathogenesis Mechanism of Diamond-Blackfan Anemia Explored Through Regulation of Proteostasis

Tatsuya Yamakawa1, Chiaki Yoshino1, Rika Nishimura1, Minako Fujii1, Megumi Narita1, Tsuyoshi Tabata1,2, Megumu Saito1, ○Mio Iwasaki1 (1. Center for iPS Cell Research and Application, Kyoto University, 2. Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University)
Comment()

[3PS-02-05(3P-567)]Ex vivo amplification of human iPSC-derived hematopoietic stem/progenitor cells by a modified Lhx2 transcription factor

○Kenji Kitajima1, Takahiko Hara1,2,3 (1. Tokyo Metropolitan Institute of Medical Science, 2. Tokyo Medical and Dental Univ., 3. Tokyo Metropolitan Univ.)
Comment()

[3PS-02-06(3P-592)]Directed differentiation of human pluripotent stem cells into organ-specific mesenchyme of the diverse foregut-derived organs

○Keishi Kishimoto1,2,3, Mitsuru Morimoto1,2, Aarom M Zorn2,3 (1. Laboratory for Lung Development, RIKEN BDR, 2. CuSTOM-RIKEN BDR Collaborative Laboratory, Cincinnati Children’s Hospital, 3. Center for Stem Cell and Organoid Medicine (CuSTOM), Perinatal Institute, Division of Developmental Biology, Cincinnati Children’s Hospital)
Comment()

[3PS-02-07]Pioneer transcription factor FOXA and transcriptional repressor PRDM1 guarantee lineage fidelity by coordinating repressive chromatin state.

○Satoshi Matsui1, Marissa Granitto2, Hee-Woong Lim2, Makiko Iwafuchi2 (1. Osaka University, 2. Cincinnati Children's Hospital Medical Center)
Comment()

[3PS-02-08]Manipulation and its application of ploidy of iPS cells

Ittetsu Nakajima1,2, Grace Holmstrom3, ○Yuichiro Miyaoka1,2,4 (1. TMiMS, 2. TMDU, 3. Pitzer College, 4. Ochanomizu Univ.)
Comment()

[3PS-02-09]Generation of 8-cell-like cells (8CLCs) from human pluripotent stem cells

○Masahito Yoshihara1,2,3,4 (1. Inst. for Adv. Acad. Res., Chiba Univ., 2. Dept. of Artificial Intelligence Med., Grad. Sch. of Med., Chiba Univ., 3. WPI-PRIMe, Osaka Univ., 4. Dept. Biosci. and Nutrition, Karolinska Inst.)
Comment()

[3PS-02-10(3P-565)]Novel Transcriptome Dynamics Revealed by Time-Series RNA-Seq Analysis during Reprogramming of Somatic Cells

○Satomi Masai1,2, Yasuhiro Yunoki1, Weipeng Shi1,2, Kohei Ishihara1, Yuki Sasaki1, Risa K Kawaguchi1, Masato Nakagawa1 (1. CiRA, Kyoto Univ., 2. Grad. Sch. of Med., Kyoto Univ.)
Comment()

[3PS-02-11(3P-593)]Control of cell fate by manipulation of dynamics of gene regulatory network

○Yusuke Tarumoto1, Seiichi Sugino1, Yuhei Yamauchi1, Masato Ishikawa1, Yusuke Seto1, Fumi Wagai1, Mototsugu Eiraku1, Atsushi Mochizuki1, Kosuke Yusa1 (1. LiMe, Kyoto Univ.)
Comment()

[3PS-02-12(3P-576)]Translation Initiation Factor EIF3H is Essential for Maintaining Pluripotency in Human Pluripotent Stem Cells

○Satoshi Suzuki1, Chikako Okubo1, Michiko Nakamura1, Mari Hamao1, Kazutoshi Takahashi1 (1. Kyoto University, Ctr.for iPS cell res. appl. (CiRA))
Comment()

[3PS-02-13(3P-608)]Extracellular extrusion of syntaxin4 and its biological significance in early embryogenesis

○Sae Nozaki1, Yohei Hirai1 (1. Kwansei Gakuin University)
Comment()

[3PS-02-14(3P-570)]Functional analysis and therapeutic applications of Ephrin receptors expressed in human pluripotent stem cells

○Atsushi Intoh1, Akira Kurisaki1 (1. Nara Institute of Science and Technology)
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Conclusion