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Wed. Dec 3, 2025

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Morphogens regulate chromosome segregation fidelity across human early lineage specification by modulation of DNA replication stress

During development, active cell proliferation and fate determination occur simultaneously, shaping the functional organism. While the molecular basis of signaling pathways regulating pluripotency and cell-fate determination has been extensively studied, the relationship between these processes and genome inheritance remains poorly understood. This symposium aims to bring together researchers from these fields to explore how genome maintenance is regulated during development, and to discuss the interaction of these processes.

【E】Shaping genome and embryo during development

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-05-06]Morphogens regulate chromosome segregation fidelity across human early lineage specification by modulation of DNA replication stress

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