The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[1AS-05]【E】Shaping genome and embryo during development

Wed. Dec 3, 2025 9:00 AM - 11:00 AM JST
Wed. Dec 3, 2025 12:00 AM - 2:00 AM UTC
Room 5(Pacifico Yokohama Conference Center 3F, 304)
Organizer: Tomomi Tsubouchi (National Institutes of Natural Sciences), Asami Oji (RIKEN)
During development, active cell proliferation and fate determination occur simultaneously, shaping the functional organism. While the molecular basis of signaling pathways regulating pluripotency and cell-fate determination has been extensively studied, the relationship between these processes and genome inheritance remains poorly understood. This symposium aims to bring together researchers from these fields to explore how genome maintenance is regulated during development, and to discuss the interaction of these processes.
9:00 AM - 9:05 AM JST(12:00 AM - 12:05 AM UTC)

Introduction

9:05 AM - 9:20 AM JST(12:05 AM - 12:20 AM UTC)

[1AS-05-01]Regulation of DNA replication in embyronic stem cells

○Tomomi Tsubouchi1,2, Kiminori Kurashima1,3, Pandey Praveen4, Chabes Andrei4, Acebron Sergio3 (1. Shizuoka University, 2. NIBB, 3. Heidelberg Univ., 4. Umea Univ.)
Comment()
9:20 AM - 9:40 AM JST(12:20 AM - 12:40 AM UTC)

[1AS-05-02]The impact of nuclear compartmentalization on DNA replication control

○Asami Oji1, Kosuke Yusa2, Izumi Noda1, Takako Ichinose1, Yoshiko Kondo1, Ichiro Hiratani1 (1. RIKEN BDR, 2. Institute for Life and Medical Sciences, Kyoto University)
Comment()
9:40 AM - 10:00 AM JST(12:40 AM - 1:00 AM UTC)

[1AS-05-03(1P-614)]A role for active protein degradation on the tempo of mouse and human neural differentiation

○Shota Nakanoh1, Loukik Doshi1, Lorena Garcia-Perez2, Chiara Azzi1, Hayley Carr1, Despina Stamataki2, Lu Yu1, David Oxley1, Simon Andrew1, James Briscoe2, Teresa Rayon1 (1. Babraham Institute, 2. The Francis Crick Institute)
Comment()
10:00 AM - 10:20 AM JST(1:00 AM - 1:20 AM UTC)

[1AS-05-04]Chromosome manipulation-mediated next-generation developmental bioengineering

○Takashi Ishiuchi1 (1. Univ of Yamanashi)
Comment()
10:20 AM - 10:40 AM JST(1:20 AM - 1:40 AM UTC)

[1AS-05-05(1P-113)]Transgenerational Inheritance of Epigenetic Memory in Mammals

○Yuta Takahashi1 (1. Kumamoto University)
Comment()
10:40 AM - 11:00 AM JST(1:40 AM - 2:00 AM UTC)

[1AS-05-06]Morphogens regulate chromosome segregation fidelity across human early lineage specification by modulation of DNA replication stress

○Anchel de Jaime-Soguero1,2 (1. Université Libre de Bruxelles (ULB), Belgium, 2. Center for Organismal Studies (COS), University of Heidelberg, Germany)
Comment()
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