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Wed. Dec 3, 2025

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Vertex remodeling by PAK4 and Afadin maintains epithelial integrity and barrier function

Cells form collectives to create an individual organism, often clustering with the same type. While intercellular adhesion via adhesion molecules is well known for signal transduction, material transfer through cellular protrusions, tunneling nanotubes, and extracellular vesicles also play a key role. This symposium explores adhesion, morphogenesis, and signaling in collective cell behavior based on recent findings.

【E】Regulation of Cellular Collective Dynamics Dependent on Intercellular Material Transport and Adhesion-mediated Interactions

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-06-06(1P-420)]Vertex remodeling by PAK4 and Afadin maintains epithelial integrity and barrier function

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