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Wed. Dec 3, 2025

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Polycomb Repressive Complex Establishes H3K27me3 Mega-Domains during Neocortical Maturation

Gene expression regulation in animals is governed by diverse mechanisms, including signaling pathways, transcription factors, chromatin regulation, transposable elements, and three-dimensional genome structures. These regulatory mechanisms are not only involved in biological processes such as embryogenesis, aging, and disease onset but also contribute to species-specific regulatory systems that have played a role in the evolution of life. This symposium brings together researchers employing in vitro and in vivo approaches to elucidate biological phenomena and understand pathologies caused by disruptions in regulatory mechanisms. The goal is to discuss the diversity of gene expression regulatory systems and explore future perspectives in this field.

【E】The Frontiers and New Advances in Gene Expression Regulation Research

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-15-06]Polycomb Repressive Complex Establishes H3K27me3 Mega-Domains during Neocortical Maturation

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