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Wed. Dec 3, 2025

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The Zinc–MTF-1–Metallothionein axis contributes to ferroptosis resistance in human cells

Metals, such as zinc, iron, copper and manganese, etc, play fundamental roles to regulate various proteins, and their homeostasis is controlled by metal transporters. Dysfunction of metal transporters causes human diseases, further highlighting metal transporters as important drug target molecules. In this symposium, we will discuss and share the recent advances of metal transporters from structures and functions, and their biological relevance in molecular basis.

【E】New insights into the metal transporters: structure, functions, disease, and drug development

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1PS-08-06]The Zinc–MTF-1–Metallothionein axis contributes to ferroptosis resistance in human cells

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