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MukBEF and Topoisomerase IV solve DNA entanglements produced by transcription and replication in <em>Escherichia coli.</em>

Chromosomes are dynamically organized in three-dimensional space to allow the proper expression, repair and duplication of the genetic material. By introducing new insights from cutting-edge techniques such as genome-wide sequencing and single-molecule analyses, this symposium aims to shed light on the mechanisms controlling chromosome structure and their relationship with diseases.

【E】Mechanistic insight into the three-dimensional organization of chromosomes

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1PS-09-06]MukBEF and Topoisomerase IV solve DNA entanglements produced by transcription and replication in Escherichia coli.

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