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Wed. Dec 3, 2025

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Quantitative imaging of subcellular GTP/GDP ratios in mammalian cells using a fluorescence lifetime-based biosensor

GTP is not just a fundamental energy molecule but, like a second messenger, actively regulates metabolic balance through its spacious-temporal concentration. GTP is also involved in inter-cellular and whole-body metabolism in higher organisms. Thus, the evolution of GTP metabolism seems to be strengthening life and has emerged as a drug-discovery target. This symposium will discuss the advances of GTP biology and associated technological developments.

【J】Advances in GTP biology

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[2AS-13-04]Quantitative imaging of subcellular GTP/GDP ratios in mammalian cells using a fluorescence lifetime-based biosensor

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