Session Details
[2AS-13]【J】Advances in GTP biology
Thu. Dec 4, 2025 9:00 AM - 11:00 AM JST
Thu. Dec 4, 2025 12:00 AM - 2:00 AM UTC
Thu. Dec 4, 2025 12:00 AM - 2:00 AM UTC
Room 13(Pacifico Yokohama Conference Center 4F, 418)
Organizer: Koh Takeuchi (The University of Tokyo), Atsuo T. Sasaki (University of Cincinnati College of Medicine)
GTP is not just a fundamental energy molecule but, like a second messenger, actively regulates metabolic balance through its spacious-temporal concentration. GTP is also involved in inter-cellular and whole-body metabolism in higher organisms. Thus, the evolution of GTP metabolism seems to be strengthening life and has emerged as a drug-discovery target. This symposium will discuss the advances of GTP biology and associated technological developments.
[2AS-13-01]Unraveling the functional evolution of GTP by precise genetic and pharmacological control of key enzymes.
○Koh Takeuchi Takeuchi1 (1. The Univ. Tokyo,)
[2AS-13-02]Data-driven multi-omics analysis to reveal the landscape of GTP sensor regulatory network that reconciles the imbalance of metabolism
○Risa Karakida Kawaguchi1,2 (1. UTokyo, 2. Kyoto Univ.)
[2AS-13-03]Trans-scale Structural Analysis: Connecting the Atomic and Macroscopic Worlds for the Future of Structural Biology
○Toshiya Senda1 (1. High Energy Accelerator Research Organization (KEK))
[2AS-13-04]Quantitative imaging of subcellular GTP/GDP ratios in mammalian cells using a fluorescence lifetime-based biosensor
○Loan Thi Ngoc Nguyen1, Cong Quang Vu2, Satoshi Arai1,2 (1. Division of Nano Life Science, Kanazawa University, 2. WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University)
[2AS-13-05]Hepatic pathology in congenital myopathy: Visualizing GTP dynamics in a zebrafish model
○Toshikatsu Hanada1 (1. Oita University Faculty of Medicine)
[2AS-13-06]ChatGTP—Fellowship and Synergy Driving Innovations in GTP Biology
○Atsuo T Sasaki1 (1. Univ. Cincinnati College of Medicine/Keio Univ./Hiroshima Univ.)