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Wed. Dec 3, 2025

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SDHAF1 Driven Complex II Activation Confers Metabolic Resilience in Aged Hematopoietic Stem Cells

In old age and frailty, impaired "resilience" causes a gradual decline of daily activity and the incidence of multiple diseases. SASP derived from senescent cells that accumulate in old individuals induces a decrease in resilience. Senothrerapy is advocated for repairing resilience. Metabolic resilience is one of them, whose latest findings will be presented and discussed.

【J】Aberrant metabolic resilience as aging mechanisms

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[2PS-10-03]SDHAF1 Driven Complex II Activation Confers Metabolic Resilience in Aged Hematopoietic Stem Cells

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