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Age-related changes in the mode of inheritance of mutant mitochondrial DNA during oogenesis.

In old age and frailty, impaired "resilience" causes a gradual decline of daily activity and the incidence of multiple diseases. SASP derived from senescent cells that accumulate in old individuals induces a decrease in resilience. Senothrerapy is advocated for repairing resilience. Metabolic resilience is one of them, whose latest findings will be presented and discussed.

【J】Aberrant metabolic resilience as aging mechanisms

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[2PS-10-05]Age-related changes in the mode of inheritance of mutant mitochondrial DNA during oogenesis.

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