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Wed. Dec 3, 2025

Thu. Dec 4, 2025

Fri. Dec 5, 2025

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Surfactin uncovers<em> RRM2</em> as a downstream oncogenic effector of altered BAF/PBAF complexes

This session will explore the complexities of transcriptional regulation, integrating foundational chromatin studies with advanced in vivo approaches. Key topics include chromatin dynamics, the roles of transcription factors, and the functions of RNA polymerase II, presented by a leading expert in the field. Furthermore, the discussion will examine how aberrant hormone receptor activity and chromatin architecture drive prostate and breast cancer progression. The mechanisms of gene transcription in aging, cancer, and therapeutic contexts will be analyzed, with an emphasis on translating molecular insights into clinical applications.

【E】Transcriptional Research from Chromatin Dynamics to Translational Insights

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[3MS-02-03]Surfactin uncovers RRM2 as a downstream oncogenic effector of altered BAF/PBAF complexes

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