Presentation Information

[3P-171]Improved In Vivo Stability of EGF-mRNA Through Optimization of Chemical Modifications in the Poly(A) Tail

○Ittoku Kikuchi1, Atsushi Hashimoto1, Yuma Kunitomo1, Hiroki Yamada1, Keiko Kobayashi1, Kazuhiro Soshiroda1, Hiromi Aman1, Masakazu Honma1, Yasuaki Kimura4, Junichiro Yamamoto1, Yasuhisa Shiraishi1, Satoshi Uchida2,3, Hiroshi Abe4,5,6,7, Hiroto Iwai1 (1. Research Division, Kyowa Kirin Co., Ltd. , 2. Department of Advanced Nanomedical Engineering, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, 3. Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, 4. Department of Chemistry, Graduate School of Science, Nagoya University, 5. Research Center for Materials Science, Nagoya University, 6. CREST, Japan Science and Technology Agency, 7. Institute for Glyco-core Research (iGCORE), Nagoya University)

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