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Wed. Dec 3, 2025

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Mechanism of totipotent-like state reactivation in mouse embryonic stem cells

Although a fertilized egg establishes totipotency through gamete fertilization and subsequently advances along diverse developmental pathways under fate regulation, many aspects of this process remain unknown. The key to understanding these processes lies in the genetic functions and epigenetic mechanisms involved in the acquisition of totipotency and pluripotency. In this symposium, we will share the latest insights into these molecular bases and introduce new developments in totipotent fate control powered by emerging technologies, including synthetic biology-based in vitro embryonic modeling.

【J】Mechanisms of Cell Fate Control in Totipotent Cells

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[3PS-05-01]Mechanism of totipotent-like state reactivation in mouse embryonic stem cells

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