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Novel histone acylation and epigenetic regulation induced by food-derived carboxylic acids

Recent high-sensitivity mass spectrometry has revealed the presence of various long- and short-chain acylation derived from metabolites in Lys and Cys residues of proteins. It is becoming clear that such acylation is involved in the regulation of environmental responses and cell functions, but this is an unexplored field in both biochemistry and cell biology. Therefore, we will introduce the latest topics on protein acylation from various perspectives and discuss what is interesting about acylation and what are the bottlenecks.

【J】Biology of Acylation

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[3PS-09-05]Novel histone acylation and epigenetic regulation induced by food-derived carboxylic acids

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