The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[3PS-09]【J】Biology of Acylation

Fri. Dec 5, 2025 2:20 PM - 4:20 PM JST
Fri. Dec 5, 2025 5:20 AM - 7:20 AM UTC
Room 9(Pacifico Yokohama Conference Center 4F, 411+412)
Organizer: Takashi Umehara (Ritsumeikan University), Saori Kosono (The University of Tokyo)
Recent high-sensitivity mass spectrometry has revealed the presence of various long- and short-chain acylation derived from metabolites in Lys and Cys residues of proteins. It is becoming clear that such acylation is involved in the regulation of environmental responses and cell functions, but this is an unexplored field in both biochemistry and cell biology. Therefore, we will introduce the latest topics on protein acylation from various perspectives and discuss what is interesting about acylation and what are the bottlenecks.
2:20 PM - 2:22 PM JST(5:20 AM - 5:22 AM UTC)

Introduction

2:22 PM - 2:39 PM JST(5:22 AM - 5:39 AM UTC)

[3PS-09-01]Bacterial acyl modifications as a potential mechanism for dynamic regulation of metabolic flux

○Saori Kosono1 (1. The University of Tokyo)
Comment()
2:39 PM - 2:56 PM JST(5:39 AM - 5:56 AM UTC)

[3PS-09-02]Metabolic Regulation of Lysine Acylation by Short Chain Fatty Acids

○Takeshi Tsusaka1 (1. University of California San Francisco)
Comment()
2:56 PM - 3:13 PM JST(5:56 AM - 6:13 AM UTC)

[3PS-09-03]Membrane trafficking of N-myristoylated proteins specifically acquired in the protozoan parasites

○Yumiko Saito-Nakano1 (1. Dept. Parasitol., Natl. Inst. Inf. Dis. JIHS.)
Comment()
3:13 PM - 3:28 PM JST(6:13 AM - 6:28 AM UTC)

[3PS-09-04(3P-909)]Growth phase diets, rich in long- and short-chain fatty acids and a branched-chain amino acid, diminish histone acetyltransferase Gcn5 function and shorten adult lifespan

Shoko Mizutani1, Yukako Hattori2, ○Tadashi Uemura3 (1. Kyoto Univ. GSB, 2. Kyoto Univ. GSB, Hakubi, 3. Kyoto Univ. GSB, LiMe)
Comment()
3:28 PM - 3:45 PM JST(6:28 AM - 6:45 AM UTC)

[3PS-09-05]Novel histone acylation and epigenetic regulation induced by food-derived carboxylic acids

○Akihiro Ito1 (1. Tokyo Univ. of Pharm. and Life Sci.)
Comment()
3:45 PM - 4:02 PM JST(6:45 AM - 7:02 AM UTC)

[3PS-09-06]What is the role of lysine acylation in the inheritance of epigenetic information?

○Takashi Umehara1 (1. College Pharm. Sci., Ritsumeikan Univ.)
Comment()
4:02 PM - 4:17 PM JST(7:02 AM - 7:17 AM UTC)

[3PS-09-07(3P-104)]An approach to acylation analysis from the perspective of data science.

○Naoshi Dohmae1 (1. RIKEN CSRS)
Comment()
4:17 PM - 4:20 PM JST(7:17 AM - 7:20 AM UTC)

Conclusion

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