Session Details
[1AS-10]【J】The Changing shape of the cell nucleus
Wed. Dec 3, 2025 9:00 AM - 11:00 AM JST
Wed. Dec 3, 2025 12:00 AM - 2:00 AM UTC
Wed. Dec 3, 2025 12:00 AM - 2:00 AM UTC
Room 10(Pacifico Yokohama Conference Center 4F, 413)
Organizer: Soichiro Yamanaka (The University of Tokyo), Miho Ohsugi (The University of Tokyo)
The symposium will broadly present research findings related to “changes in nuclear shape". In organisms undergoing closed mitosis, the nucleus exhibits dynamic shape changes throughout the cell cycle. Similarly, in organisms undergoing open mitosis, abnormalities in cell division have been shown to result in nuclear malformations. Furthermore, the nucleus is known to adopt various shapes during processes such as the differentiation of neurons, germ cells, and fertilized eggs, as well as during aging and cancer development. Accordingly, this symposium aims to enhance our understanding of "when nuclear shape changes occur" and "what happens when the nuclear shape changes" through presentations focused on nuclear shape.
Introduction
[1AS-10-01]Lamin Dynamics and Nuclear Morphology in Perinatal Male Germ Cells of Mice
Tatsuya Fujisawa2, Mikiko C Siomi2, ○Soichiro Yamanaka1 (1. Hamamatsu University School of Medicine, 2. Department of Biological Sciences, Graduate School of Science, The University of Tokyo)
Q & A for Each Presentation
[1AS-10-02(1P-941)]Lamin A/C-driven nuclear envelope maturation is required for postnatal heart maturation
○Katano Wataru1, Alexis Stutzman2, Briana Thomas1, Melanie Gucwa1, Hanumakumar Bogireddi1, Atsuki En1,3, Kohta Ikegami1,4 (1. Cincinnati Children's Hospital Medical Center, 2. The University of Chicago, 3. Yokohama City University, 4. University of Cincinnati College of Medicine)
Q & A for Each Presentation
[1AS-10-03]Morphological and Physical Dynamics of the Nucleus in Neurons
○Yusuke Kishi1,3, Haruto Kinoshita1,2, Rinka Obata1,3, Yu Nagata1,3, Viveca Hoglund1, Koichiro Maki4, Taiji Adachi4 (1. IQB, Univ of Tokyo, 2. Faculty of Pharma, Univ of Tokyo, 3. Grad Sch of Pharma, Univ of Tokyo, 4. LiMe, Kyoto Univ)
Q & A for Each Presentation
[1AS-10-04]Morphology and Destiny of the Chloroplast Nucleoid during the Algal Life Cycle
○Yusuke Kobayashi1 (1. Ibaraki University)
Q & A for Each Presentation
[1AS-10-05(1P-349)]Selective localization of Importin-α defines functional properties of micronuclei
○Yoichi Miyamoto1, Masahiro Oka2, Hisato Saitoh3, Toyomasa Katagiri1 (1. Lab. Biofunc. Mol. Med., Natl. Inst. Biomed. Innov., Health, Nut. , 2. Dept. Reg. Infect. Cancer, Res. Inst. Micrb. Dis., Osaka Univ. , 3. Faculty Adv. Sci. Tech. (FAST), Kumamoto Univ.)
Q & A for Each Presentation
[1AS-10-06(1P-452)]Unique Division Dynamics of Multinucleated Cells Induced by Cell Fusion
○Joey Nakane1,2,4, Tomomi Tsubouchi2,3,4 (1. Basic Biology, SOKENDAI, 2. Stem cell biology, NIBB, 3. Applied Life Sciences, Agriculture, Shizuoka Univ., 4. Agriculture, Graduate School of Integrated Science and Technology, Shizuoka Univ.)
Q & A for Each Presentation
[1AS-10-07]Nuclear shape and mechanical dynamics in early mouse embryos
○Yuta Shimamoto1,2 (1. National Institute of Genetics, 2. SOKENDAI)
Q & A for Each Presentation
[1AS-10-08]Safeguarding Mammalian Zygotes from Multinucleation: Risk Factors and Preventive Mechanisms
Shou Suzuki2, Tatsuki Kakuta2, Midori Kajitani1, ○Miho Ohsugi1,2 (1. Dep. of Biol. Sci., Grad. Shc. of Sci., Univ. of Tokyo, 2. Dep. of Life Sci., Grad. Sch. of Arts and Sci., Univ. of Tokyo)